# Life Sciences Grade 12 P2 Gauteng Mock 2022 QP (Eng)

> Grade 12 Life Sciences Paper 2 question paper from the Gauteng Mock Exam 2022 (English), 21 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/gr12-life-sciences-p2-english-sep-2022-question-paper/9642904d-c9eb-4e6a-baf0-c0e969fc35c8
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Language: English
- Document type: Question paper
- Year: 2022
- Exam period: Gauteng Mock Exam
- Paper: 2
- Curriculum: CAPS
- Pages: 21

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## About this document

Life Sciences · Grade 12 · Gauteng Mock Exam · 2022 · English. Question paper, 21 pages. Read online or download the PDF.

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- [Gr12 Life Sciences P2 (English) SEP 2022 Possible Answers](https://www.hlayiso.com/library/gr12-life-sciences-p2-english-sep-2022-possible-answers/17f73f27-a44f-41f5-b5d9-656090338f3e) — Memo · 2022 · Eng

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PREPARATORY EXAMINATION
             2022
              10832

          LIFE SCIENCES

            PAPER 2

                          TIME:      2½ hours

                          MARKS: 150

                          21 pages

                                                P.T.O.

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                                       LIFE SCIENCES                                   2
                                       (Paper 2)                            10832/22

INSTRUCTIONS AND INFORMATION

1.   Answer ALL the questions in the ANSWER BOOK.

2.   Start the answers to EACH question at the top of a NEW page.

3.   Number the answers correctly according to the numbering system used in this
     question paper.

4.   Present your answers according to the instructions of each question.

5.   ALL drawings must be done in pencil and labels in blue or black ink.

6.   Draw diagrams, flow charts or tables only when asked to do so.

7.   The diagrams in this question paper are NOT necessarily drawn to scale.

8.   Do NOT use graph paper.

9.   You must use a non-programmable calculator, protractor and a compass where
     necessary.

10. Write neatly and legibly.

                                                                                       P.T.O.

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                                                  LIFE SCIENCES                          3
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SECTION A

QUESTION 1

1.1   Various options are provided as possible answers to the following questions.
      Choose the answer and write only the letter (A – D) next to the question numbers
      (1.1.1 to 1.1.8) in the ANSWER BOOK, e.g., 1.1.9 E.

      1.1.1   Which of the following is a function of meiosis?

              A       Reduces genetic variation in a species
              B       Cancels out the doubling effect of fertilisation
              C       Doubles the amount of mitochondrial DNA
              D       Slows down evolutionary changes in a species

      1.1.2   Natural selection acts upon an organism’s ...

              A       habitat.
              B       genotype.
              C       phenotype.
              D       environment.

      1.1.3   Give the correct sequence of events which occur during
              METAPHASE 1 and ANAPHASE 1 of meiosis, respectively:

              (i)      Homologous chromosomes arrange themselves at the equator.
              (ii)     Chromosomes are pulled to the poles.
              (iii)    Spindle fibres shorten.
              (iv)     Spindle fibres attach to the centromere.

              A       (i), (ii), (iii) and (iv)
              B       (i), (ii), (iv) and (iii)
              C       (i), (iv), (iii) and (ii)
              D       (iv), (iii), (ii) and (i)

      1.1.4   A genetic disorder that results in the absence of blood-clotting factors
              is ...

              A       polydactyly.
              B       albinism.
              C       Down syndrome.
              D       haemophilia.

                                                                                         P.T.O.

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1.1.5   Which process will result in genetic variation in gametes at the end of
        meiosis?

        A     Crossing-over
        B     Cytokinesis
        C     Random fertilisation
        D     DNA replication

1.1.6   A pair of homologous chromosomes involved in normal meiosis in an
        ovary carries the alleles shown below.

        Possible chromosomes in the ova produced would include:

             A              B              C               D

1.1.7   Hominids are believed to have evolved in Africa because ...

        A     the oldest hominid fossils have been found in Africa.
        B     the most hominid fossils have been found in Africa.
        C     monkey fossils were found in Africa.
        D     Africa is the oldest continent.

1.1.8   The scientist who discovered Australopithecus sediba in the Cradle of
        Humankind is:

        A     Raymond Dart
        B     Mary Leakey
        C     Lee Burger
        D     Donald Johanson
                                                                           (8 x 2) (16)

                                                                                    P.T.O.

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1.2   Give the correct biological term for each of the following descriptions. Write
      only the term next to the question numbers (1.2.1 to 1.2.7) in the ANSWER
      BOOK.

      1.2.1   The type of dominance resulting in an intermediate phenotype in the
              heterozygous condition

      1.2.2   Point of contact between two homologous chromosomes where the
              exchange of genetic material occurs

      1.2.3   The monomer of a nucleic acid

      1.2.4   Opening in the base of the skull through which the spinal cord passes

      1.2.5   A genetic disorder due to the absence of proteins in the photoreceptors
              of the eye

      1.2.6   Two identical alleles for a particular characteristic

      1.2.7   The number, shape and arrangement of all the chromosomes in the
              nucleus of a somatic cell
                                                                            (7 x 1)     (7)

                                                                                        P.T.O.

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1.3     Indicate whether each of the statements in COLUMN I applies to A ONLY, B
        ONLY, BOTH A and B or NONE of the items in COLUMN II. Write A only, B
        only, both A and B or none next to the question numbers (1.3.1 to 1.3.3) in the
        ANSWER BOOK.

                          COLUMN I                                 COLUMN II
      1.3.1     Different pairs of alleles of a gene
                                                     A       Genetic variation
                which separate independently during
                gamete formation                     B       Mendel’s law of segregation
      1.3.2     One set of chromosomes                 A     Triploid
                                                       B     Diploid
      1.3.3     Gonosomes present                      A     Gametes
                                                       B     Somatic cells
                                                                                    (3 x 2)   (6)

1.4     The diagram below shows the process of protein synthesis.

                                        Process of protein synthesis
                              Y

                                                                   X
                                         v

                                                W
                                                                          Z

                                                                          T

        1.4.1     State the TWO organelles in the cell that are directly involved in the
                  process mentioned above.                                                         (2)

        1.4.2     How many codons are present in molecule Y?                                       (1)

        1.4.3     Name the bond represented by T.                                                  (1)

        1.4.4     Give the anticodon represented by Z.                                             (1)
                                                                                                   (5)

                                                                                              P.T.O.

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1.5   In a certain breed of cattle, the head colour may be white, black or black and
      white. The alleles controlling the inheritance of the colour of the hair on the
      head is W (white hair) and B (black hair).

      A black and white-headed bull mates with a black-headed cow.

                                               X
                              bull                        cow

      1.5.1   Name the type of inheritance shown above.                                       (1)

      1.5.2   Give the genotype of the bull.                                                  (1)

      1.5.3   Give the phenotypic ratios of all possible offspring.                           (2)
                                                                                              (4)

1.6   In the breeding season, male anole lizards court females by bobbing their
      heads (moving up and down) while displaying a colourful throat patch. The
      ability of anoles to bob their heads fast (B) is dominant over slow-bobbing
      heads (b).

      The allele for red throat patches (R) is dominant over yellow throat patches (r).

      A male lizard heterozygous for head bobbing and homozygous for the red throat
      patch mates with a female that is also heterozygous for head bobbing but has a
      yellow throat patch.

      1.6.1   State the type of genetic cross represented above.                              (1)

      1.6.2   Give the:

              (a)    Genotype of the female lizard                                            (2)
              (b)    Possible gametes produced by the male lizard                             (2)

      1.6.3   State the reproductive isolation mechanism illustrated in this example.         (1)
                                                                                              (6)

                                                                                          P.T.O.

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1.7   Hominins are a group that consists of modern humans, extinct human species,
      and all of their immediate ancestors.

      Evidence of tools that were used by hominins that has been found is classified
      into three tool traditions: Oldowan, Acheulian and Mousterian.

        Years Ago                 Hominins                Major Tool Traditions

               10.000
                            Modern humans

               40.000            Neanderthals
                                                             Mousterian

              100.000

              250.000

                                     H.                              Acheulian
                                     heidelbergensis
              500.000

         1.000.000

                               H. erectus
         1.500.000
                                             H. habilis

         2.000.000                                            Oldowan

         2.500.000

      1.7.1    Name the type of evidence for evolution that is represented by tool
               traditions.                                                                   (1)

      1.7.2    Give the scientific name of modern humans.                                    (1)

      1.7.3    Which hominin(s) used the oldest tool tradition?                              (2)

      1.7.4    Which tool tradition is associated with H. heidelbergensis?                   (1)

      1.7.5    Suggest which tool tradition was the most advanced.                           (1)
                                                                                             (6)

                                                                     TOTAL SECTION A:        50

                                                                                         P.T.O.

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                                         LIFE SCIENCES                                  9
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SECTION B

QUESTION 2

2.1   Four soldiers are missing from an army unit. The unit finds the body of one of
      the missing soldiers who has been killed in an explosion. There are no
      identifiable features on the body and the identification tags are missing.

      The army asks the parents of the four missing soldiers for a DNA sample so
      that they can compare the DNA profiles of the parents with the DNA profile of
      the soldier that was killed.

                    Parents             Parents            Parents           Parents
      Soldier
                   A       B          C        D          E        F        G       H

      2.1.1     Which set of parents are the parents of the dead soldier?                   (1)

      2.1.2     Explain your answer to QUESTION 2.1.1.                                      (2)

      2.1.3     Mention ONE other use of DNA profiling.                                     (1)
                                                                                            (4)

                                                                                        P.T.O.

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2.2   The diagram below represent DNA replication.

      2.2.1   Name the phase of the cell cycle during which DNA replication takes
              place.                                                                  (1)

      2.2.2   Identify the type of error that occurred in strand 3.                   (1)

      2.2.3   Give the base pair showing the error referred to in QUESTION 2.2.2.     (1)

      2.2.4   Describe the consequences of the error during DNA replication.          (2)

      2.2.5   Tabulate TWO differences between DNA replication and transcription.     (5)
                                                                                     (10)

                                                                                     P.T.O.

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2.3   Table 1 shows the DNA base triplets that code for different amino acids.

      Table 1

                     Amino acid                 Base triplet of DNA template
                     Proline                                GGG
                     Phenylalanine                           AAA
                     Glycine                                 CCT
                     Lysine                                  TAT
                     Tryptophan                              CGT
                     Alanine                                 TTA

      Table 2 shows a part of the sequence of anticodons that code for a polypeptide.

      Table 2

                AMINO ACID            1           2            3          4
                ANTICODON            UUA         CCU         AUA         UUA

      2.3.1     Identify, using the tables above, amino acids 2 and 4.                    (2)

      2.3.2     How many amino acids will be coded for by the anticodons in Table 2?      (1)

      2.3.3     Name and describe the process that uses anticodons to make proteins.      (5)
                                                                                          (8)

                                                                                         P.T.O.

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2.4   The diagram below shows an error that occurred during meiosis in humans.

                        Structure 1
                        Structure 2
                                                      Cell A

                               Gamete I         Gamete II

      2.4.1   According to the diagram, during which phase of meiosis did the error
              mentioned occur?                                                         (1)

      2.4.2   (a)   Which structure (1 or 2) in Cell A is the nuclear membrane?        (1)
              (b)   How many chromosomes are shown in the diagram?                     (1)

      2.4.3   State the origin of the chromosomes in Cell A.                           (2)

      2.4.4   Draw a diagram of the phase in Cell A before the error occurred.         (4)

      2.4.5   In humans, how many chromosomes would be present in Gamete II?           (1)
                                                                                      (10)

                                                                                      P.T.O.

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2.5   The table below shows the frequency of different blood groups in the world.

                   Blood Group                                Frequency (%)
                        A                                         33,5
                        B                                         16,0
                        O                                         45,0
                       AB                                          5,5
                                                       [Source: https://www.worldatlas.com]

      2.5.1   How many alleles …

              (a) control blood group inheritance?                                             (1)
              (b) are passed on from mother to offspring?                                      (1)

      2.5.2   Based on the table, which is the least frequent of the blood groups?             (1)

      2.5.3   Plot a pie chart using the data above.                                           (6)
                                                                                               (9)

                                                                                              P.T.O.

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2.6   Cheetahs, Acinonyx jubatus, are carnivores found in the dry grasslands and woodlands
      of Southern Africa. Cheetahs normally have spotted fur. However, the king cheetah is a
      rare variety of A. jubatus that has inherited striped fur markings.

                    Cheetah with spots                     King cheetah

      With declining cheetah populations in the wild, a breeding programme was
      started to increase the number of cheetahs to introduce into the wild. Using two
      breeding pairs, eight cubs were born. The first breeding pair produced four
      cubs and from the second pair, four cubs were also born.

      The results of the two matings are shown in the table below:

       Breeding pair               Parents                   Offspring
                                                      3 with spotted fur
              1           Spotted fur x spotted fur
                                                      1 with striped fur
                                                      2 with spotted fur
              2           Spotted fur x striped fur
                                                      2 with striped fur

      2.6.1   Using the alleles N and n, state the possible genotypes of the:

              (a)     Striped fur cheetah                                                 (1)
              (b)     Spotted fur parent in the second cross                              (1)

      2.6.2   Which law of Mendel is demonstrated in the above investigation?             (1)

      2.6.3   Use a genetic cross to show the genotype and phenotype ratio of the
              offspring produced by breeding pair 2.                                      (6)
                                                                                          (9)

                                                                                         [50]

                                                                                         P.T.O.

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                                         LIFE SCIENCES                                  15
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QUESTION 3

3.1   The pedigree diagram below traces the inheritance of a genetic disorder known
      as Rett syndrome resulting in extreme mental disability. It is caused by a
      dominant allele carried on the X chromosome (XR).

                    Key:

                           Normal male

                           Male with Rett syndrome

                           Normal female

                           Female with Rett syndrome

      3.1.1   Give evidence from the diagram which suggests that Rett syndrome is
              caused by a dominant allele.                                               (1)

      3.1.2   How many females in the family are affected by Rett syndrome?              (1)

      3.1.3   Explain why males are less likely than females, to be affected by Rett
              syndrome.                                                                  (4)

      3.1.4   Individual 9 marries an unaffected female.

              (a)    What is the percentage probability of having affected daughters?    (1)
              (b)    Give the daughters’ genotype.                                       (1)
                                                                                         (8)

                                                                                        P.T.O.

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3.2   The male fiddler crab has one normal sized claw and one giant sized claw
      (Photograph B). Female fiddler crabs have two small claws that are the same
      size (Photograph A).

      There is a range of sizes of giant claws in the male fiddler crab population. The
      male waves the giant claw to attract females during mating season.

                       Female                                 Male

                                                        1 normal        1 giant
                   2 normal claws
                                                          claw           claw

      A researcher investigated the importance of the claw size of males for
      successful mating during three trials.

      He placed:

         15 male fiddler crabs with different sized giant claws into a cage
         15 female fiddler crabs into the same cage

                                                                                          P.T.O.

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The bar graph below shows the percentage of male crabs with different giant
claw sizes that successfully mated during the three investigations.

                               THE EFFECT OF GIANT CLAW SIZE ON REPRODUCTIVE
                            SUCCESS IN MALE FIDDLER CRABS IN THREE INVESTIGATION
                                                    TRIALS
                       90
                       80
                       70

  Mating success (%)
                       60
                       50
                                                                      Male crabs with larger
                       40                                             claws
                       30                                             male
                                                                      Male crabs with smaller
                                                                      claws
                                                                      claws
                       20
                       10
                        0
                                  1             2             3
                                       Investigation trials

3.2.1                       Identify the:

                            (a) Independent variable                                                       (1)
                            (b) Dependent variable                                                         (1)

3.2.2                       Describe how the researcher ensured the reliability of the investigation.      (1)

3.2.3                       Give TWO ways in which the researcher ensured that the results were
                            valid.                                                                         (2)

3.2.4                       Explain ONE precautionary measure that the researcher would need to
                            take for this investigation.                                                   (2)

3.2.5                       Discuss how Lamarck would have explained the presence of the one
                            giant claw in male fiddler crabs.                                              (4)
                                                                                                          (11)

                                                                                                          P.T.O.

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                                             LIFE SCIENCES                                  18
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3.3   Ancon sheep were a domesticated sheep that were bred from a single affected
      lamb, born with a recessive dwarf mutation.

      They had very short legs that were considered an advantage for farmers because
      they were unable to jump over ordinary stone walls or fences.

                    [Source: https://answersingenesis.org/genetics/mutations/
                                      ancon-sheep-just-another-loss-mutation/]

      3.3.1   According to the text, what caused the short legs in this breed of
              sheep?                                                                         (1)

      3.3.2   (a)      Suggest a reason why the normal legged sheep would be a
                       problem for farmers.                                                  (1)
              (b)      Explain ONE benefit for the farmer keeping these Ancon sheep.         (2)

      3.3.3   Farmers used artificial selection to breed herds of Ancon sheep. Give
              the definition of artificial selection.                                        (2)
                                                                                             (6)

                                                                                            P.T.O.

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3.4   Eastern tiger snakes (Notechi scutatus) living on islands off mainland Australia
      have longer jaws than the mainland populations of snakes. The diet of island
      snakes includes large prey, such as seagull chicks, while the diet of the mainland
      snakes consists of small prey, such as frogs and mice.

      3.4.1   (a) Describe the jaw of the island snakes.                                    (1)
              (b) What is the staple diet of the mainland snakes?                           (1)

      3.4.2   (a) Give the definition of a species.                                         (2)
              (b) Describe how island and mainland snakes could have evolved into
                  different species.                                                        (7)
                                                                                           (11)

                                                                                           P.T.O.

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3.5   The graph below shows the change in the number of species as a result of
      punctuated equilibrium.

                                                                            D

                                   B
                                                                      C

        Evolution

                                  A

                                                Time

      3.5.1         Give the definition of punctuated equilibrium.                             (4)

      3.5.2         Using the letters from the graph, indicate the period of time where the
                    environment would be stable.                                               (1)

      3.5.3         Are transitional fossils associated with punctuated equilibrium?           (1)
                                                                                               (6)

                                                                                              P.T.O.

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3.6   The diagram below shows the size of the temporal muscle in a human and an
      ape. Temporal muscles attach the lower jaw to the skull in both apes and
      humans. These muscles help to open and close the jaw when chewing food.

                     SKULL A                                SKULL B

        Temporal                                Temporal
        muscles                                 muscles

              [Source: https://www.pathwayz.org/Tree/Plain/APE+VS.+HOMININ+SKULLS]

      3.6.1   Explain how skull A is better adapted to eating a diet of raw food than
              skull B with respect to:

              (a)   Temporal muscle and jaw size                                         (2)
              (b)   Dentition                                                            (2)

      3.6.2   Which skull (A or B), represents a human?                                  (1)

      3.6.3   State THREE other characteristics that humans share with African
              apes.                                                                      (3)
                                                                                         (8)

                                                                                        [50]

                                                                 TOTAL SECTION B:       100

                                                                              TOTAL:    150

                                             END

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- [Life Sciences Grade 12 NSC P2 MEMO September 2025 KZN](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-p2-memo-september-2025-kzn/f412416e-57d1-473d-886a-87c9fbb8823c) — Memo · 2025

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- [Grade 12 past papers](https://www.hlayiso.com/grade-12/past-papers)

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