# Life Sciences Grade 12 KZN June 2023 Paper & Memo

> Grade 12 Life Sciences question paper and memo from the KZN June Exam 2023, 25 pages. Read online or get the free PDF download.

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- Updated: 2026-09-28
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Question paper and memo
- Year: 2023
- Exam period: KZN June Exam
- Curriculum: CAPS
- Pages: 25

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Basic Education

KwaZulu-Natal Department of Education
REPUBLIC OF SOUTH AFRICA

(eimiag

NATIONAL
SENIOR CERTIFICATE

iT TT |

MARKS: 160

TIME: 2hrs 40mins

N.B. This question paper consists of 15 pages.

Copyright Reserved Please Turn Over

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INSTRUCTIONS AND INFORMATION
Read the following instructions carefully before answering the questions.
1. Answer ALL > questions.
2. Write ALL fevers in the ANSWER BOOK.

3. Number te anover correctly according to the numbering system used

in this qu Paper.
4. Present your answers according to the instructions of each question.
5. ALL drawings must be done in pencil and labelled in blue or black ink.
6. Draw diagrams, flow charts or tables only when asked to do so.
7. The diagrams in this question paper are NOT necessarily drawn to scale.

8. Do NOT use graph paper.

9. You must use a non-programmable calculator, protractor and a compass
where necessary.

10. Write neatly and legibly.

Copyright Reserved Please Turn Over

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SECTIONA
Question 1
1.1

Various options are provided as possible answers to the following questions.

Choose the answer and write only the letter (A to D) next to the question number

(1.1.1 tof

1.1.1

712) i in the ANSWER BOOK, for example 1.1.13. D

> process where one DNA molecule produces two identical DNA molecules
lled .

aN ‘Acteproduction.

—B=teplication.

C. translation.

D. protein synthesis

When a cell divides by meiosis it results in ..

A. four haploid gametes.

B. two diploid gametes.

C. four haploid somatic cells.
D. two haploid somatic cells.

Which ONE of the following events occurs during metaphase | of meiosis?

A. Homologous chromosomes arrange themselves at the equator
B. Centrioles move to opposite poles

C. Chromosomes arrange themselves singly at the equator

D. Splitting of the cytoplasm

Which one of the following occurs during meiosis?

A. A haploid cell gives rise to two haploid cells
B. A diploid cell gives rise to two haploid cells

C. Ahaploid cell gives rise to four haploid cells
D. Adiploid cell gives rise to four haploid cells

A type of reproductive strategy in birds where hatchlings are helpless and
unable to move and feed themselves?

A. Precocial development
B. Altricial development
C. Vivipary

D. Ovovivipary

Which ONE of the following involves the developmentlof the young inside the
uterus of the mother and where it receives nutrientsthrtough the placenta?
e 4
A. Ovipary
B. Vivipary
C. Ovovivipary
D. Amniotic egg

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1.1.7

Where are sperm cells in humans temporarily stored?

A. Vas deferens
B. Epididymis
C. Urinary bladder

1.1.9

A. Serve as a micro-filter preventing germs from entering the foetus.
B. act as a shock absorber to protect the foetus.

C. keep the foetus at a temperature lower than body temperature.
D. serve as a medium for the sperm to swim in.

The genotype for an individual with blood group Ais ...
A. A only.

B. IAI or ii.

c. Ii only.

pb. or i

1.1.10 Which ONE of the following is a function of adrenalin?

1.1.11

A. Lowering blood pressure

B. Promoting the conversion of glucose to glycogen
C. Increasing skeletal muscle tone

D. Causing the blood vessels of the skin to dilate

Which ONE of the following hormones controls metabolic rate?

A.Testosterone
B.Thyroxin

C. Growth hormone
D. Insulin

1.1.12 Which ONE of the following will occur in the human body on a cold day?

A. Vasodilation in the skin

B. Increase in the activity of sweat glands
C. Decrease in evaporation of sweat from the surface of the skin
D. Increase in blood flow to the surface of the skin

(2X 12 =24)

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1.2

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Give the correct biological term for each of the following descriptions. Write
only the term next to the question number (1.2.1 to 1.2.8) in the ANSWER
BOOK.

1.2.1
1.2.2

1.2.3
1.2.4

1.2.5
1.2.6
1.2.7
1.2.8
1.2.9
1.2.10

1.2.11

1.2.12

1.2.13

1.2.14

1.2.15

1.2.16

type of RNA containing anticodons

lhe process during which genetically identical organisms are formed using
biotechnology

A

Undifferentiated animal cells that can form any type of tissue

Type of inheritance where none of the two alleles is dominant over the other
and an intermediate phenotype is produced

The breeding of organisms by humans to achieve a desirable phenotype
The point of crossing over between two adjacent chromosomes

The organelle in a cell where translation occurs

Acondition of the cell where there is only one set of chromosomes

A hormone that stimulates ovulation in humans

The part of the brain that connects the left and right hemispheres

The blood vessel that transports deoxygenated blood from the foetus
towards the placenta

A small device that is inserted in the ear to drain fluids caused by a middle-
ear infection

The branch of the autonomic nervous system that restores an increased heart
rate back to normal

A structure in the eye that absorbs light to prevent internal reflection

The number, shape and arrangement of all the chromosomes in the nucleus
of a somatic cell

The hormone that stimulates puberty in females

(1X 16 = 16)

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1.3 Indicate whether each of the descriptions in COLUMN | applies to A ONLY, B
ONLY, BOTH A AND B or NONE of the items in COLUMN II. Write A only, B
only, both A and B or none next to the question number (1.3.1 to 1.3.10) in

the ANSWER BOOK.

7; COLUMN | COLUMN II
1.3.1 GOndition affecting the cornea of A. Astigmatism
théleye IB: Cataract
1.3.2 jHotmones secreted by the A:Prolactin
pituitary gland B: Growth hormone

1.3.3. Location of DNA in a human

A: Mitochondrion
B: Nucleus

1.3.4 First to discover the double helix
structure of DNA

A: Mendel and Watson B:
Watson and Crick

1.3.5 Contains the sugar ribose

A: DNA B:
IRNA

1.3.6 Chromosomes align at the equator

A: Metaphase |
IB: Metaphase II

1.3.7 The functional connection
between two
consecutive neurons

A: Receptor
B: Synapse

1.3.8 Result of non-disjunction
of chromosome pair 21 in
humans

A: Gamete with 22 chromosomes
B: Gamete with 24 chromosomes

1.3.9 The point of attachment of A: Locus
two overlapping chromatids B: Chiasma
1.3.10 Doubling of DNA A: Prophase |
B: Prophase II

(1X 10 = 10)
TOTAL SECTION A: [50]

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SECTION B
QUESTION 2

2.11 The diagram below shows a karyotype.

— a

1¢

ANAS UB ADRK 89 4H MN

410 14

Hh

12

hh An BASS IN BA XX KX na aw i,

23

214

2.2

How many of the following are present in the karyotype:

(a) Chromosomes (1)

(b) Autosomes (1)
(c) Gonosomes (1)

How many chromosomes would be present in the gametes

produced by this individual? (1)
Is the karyotype above that of a male or a female? (1)

(5)

The diagram below represents one of the two cells that is formed
during Telophase | of meiosis in an organism.

Draw a labelled diagram to show the cell during Anaphase II of meiosis. (5)

(5)

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2.3

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The diagram below represents a process that occurs during meiosis.

A

me

2.3.1

2.3.2
2.3.3

2.3.4

Identify parts
() A
(i) B
(iii) C
(iv) D

Give the function of part labelled B.
Name:
(a) The process occurring at C
(b) The phase in meiosis during which the process C occurs

State ONE reason why process C is important.

(1)
(1)
(1)
(1)

(1)

(1)

(1)

(1)
(8)

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2.4

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Study the diagrams below showing male and female reproductive systems.

2.4.1 Identify parts A, B and F respectively.

2.4.2 State ONE function of each of the following:

(3)

(a) The fluid produced by part C (1)
(b) Part E (1)
(c) Part F (1)

2.4.3 Give the LETTER ONLY of the organ where meiosis takes place in the:

(a) Male reproductive system

(1)

(b) Female reproductive system (1)

2.4.4 Name the type of gametogenesis that takes place in the:
(a) Male reproductive system
(b) Female reproductive system

2.4.5 State TWO functions of part H.

2.5 Describe the process of fertilisation.

2.6 Describe the process of oogenesis as it occurs in pa

(1)
(1)

(2)
(12)

(5)

(5)
(10)

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QUESTION 3
The diagrams below show different parts of the brain and the ear.

3.1

F
G

3.1.1

Identify part

(i) A

(ii) B

(iii) H

Give the LETTER and NAME of the part of the ear that absorbs
excess pressure waves from the inner ear.

Name the receptors found at part E

Describe the process of hearing

(1)
(1)
(1)
(2)
(1)

(6)
(12)

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3.2

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Study the diagram below of the sequence of events that takes place from the

fertilization of the ovum to the development of the embryo in a part of the human

female reproductive system

3.2.1 Identify:
(a) Structure C
(b) The stage of embryo development at E.
(c) The structure that develops from a combination of parts
FandH
3.2.2 Name the process that takes place:

(a) AtB

(b) | When G attaches to part F

3.2.3. Give the chromosome number of:
(a) The cells at D

(b) CellA

(1)
(1)

(1)
(1)

(1)

(1)
(7)

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3.3

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The diagram below represents the structure of a neuron.

Ly

3.3.1
3.2.2

3.2.3

3.2.4

3.3

Name the type of neuron in the diagram above. (1)
Identify parts:

(a) B (1)
(b)  F (1)
She es LETTER and NAME of the part that: "
(a) Transmits impulses away from the cell body (2)
(b) Insulates and speeds up the transmission of impulses (2)
Name the condition caused by the progressive degradation of part D (1)

Describe the reflex action that occurs when a person touches a hot pot. (6)
(15)

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3.4

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The diagram below represents parts of the endocrine system in humans.

3.4.1

3.4.2

Identify gland:
(a) A (1)
(b) B (1)

Give the LETTER and NAME of the gland that secrete a hormone
responsible for:

(a) Starting puberty in males (2)
(b) Stimulating absorption of glucose by cells (2)

(c) Making the kidney tubules permeable to water (2)
(8)

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3.5

3.6

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Read the extract below and answer the questions that follow.

The Comrades Marathon is an ultra-marathon of approximately 89 kilometres
which is_run annually in the KwaZulu-Natal province between the cities of
DurbanLand Pietermaritzburg. It is the world’s largest and oldest ultra-
marathonrace.

While running, an athlete’s body temperature increases.

Describe the negative feedback mechanism that will restore the athlete’s
body temperature to normal. (6)

The diagram below shows the structure of the human eye.

Cc
B
JA
D

3.6.1 Identify the parts labelled:

(a) A (1)

(b) B (1)
3.6.2 State ONE function of part C. : (1)

3.6.3. Describe accommodation of the eye when a person focuses on
an object that is moving away. lon (4)

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3.7

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Human blood groups are controlled by multiple alleles.

3.7.1. Name all the alleles that control blood groups

(3)
loa?
many of the alleles named in QUESTION 3.7.1 can any individual inherit
(1)
3.7.3 fon has blood group A and his wife has blood group B.
Fheir first child has blood group AB and second child has blood group O.

What can one conclude about the blood groups of their future children? (3)
3.7.4 State Mendel's principle of segregation. (2)

Use a genetic cross to show how gender in human offspring is determined by
the sex chromosomes of the parents. (6)

(15)

3.7.5

TOTAL SECTION B :110
GRAND TOTAL 7160

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Basic Education

KwaZulu-Natal Department of Education
REPUBLIC OF SOUTH AFRICA

NATIONAL
SENIOR CERTIFICATE

GRADE 12

MARKS: 160

N.B. This memorandum consists of 10 pages.

Copyright Reserved Please Turn Over

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PRINCIPLES RELATED TO MARKING LIFE SCIENCES

1.

10.

11.

12.

13.

14.

15.

16.

If more information than marks allocated is given
Stop marking when maximum marks is reached and put a wavy line and 'max' in the right-hand
margin.

If, for example,-three reasons are required and five are given
Mark the first-three irrespective of whether all or some are correct/incorrect.

If whole process is given when only a part of it is required
Read all and-credit the relevant part.

If comparisons are asked for, but descriptions are given
Accept if the differences/similarities are clear.

If tabulation is required, but paragraphs are given
Candidates will lose marks for not tabulating.

If diagrams are given with annotations when descriptions are required
Candidates will lose marks.

If flow charts are given instead of descriptions
Candidates will lose marks.

If sequence is muddled and links do not make sense
Where sequence and links are correct, credit. Where sequence and links are incorrect, do not
credit. If sequence and links become correct again, resume credit.

Non-recognised abbreviations
Accept if first defined in answer. If not defined, do not credit the unrecognised abbreviation, but
credit the rest of the answer if correct.

Wrong numbering
If answer fits into the correct sequence of questions, but the wrong number is given, it is
acceptable.

If language used changes the intended meaning
Do not accept.

Spelling errors
If recognisable, accept the answer, provided it does not mean something else in Life Sciences or if
it is out of context.

If common names are given in terminology
Accept, provided it was accepted at the national memo discussion meeting.

If only the letter is asked for, but only the name is given (and vice versa)
Do not credit.

If units are not given in measurements
Candidates will lose marks. Memorandum will allocate marks for units Separately.

Be sensitive to the sense of an answer, which may be stated in a different way.
Caption
All illustrations (diagrams, graphs, tables, etc.) must have a caption.

Copyright Reserved Please Turn Over

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SECTION A
QUESTION 1
1.41

1.1.1 BYvY

11.2AVv
11.3AV

1.1.4 DY

1.1.5 BYY

1.1.6 BYV

1.1.7 BYV

1.1.8 BYV

1.1.9 DvY

1.1.10 CvY

1.1.11 BYY

1.1.12 Cvv (2x12) (24)

1.2

1.2.14tRNA v /transfer RNA

1.2.2 Cloningy

1.2.3 Stem cellsY¥

1.2.4 Incomplete dominanceY

1.2.5 Artificial selectionY /selective breeding
1.2.6 Chiasmav

1.2.7 Ribosomev

1.2.8 Haploidv

1.2.9 LHv / Leteinizing hormone

1.2.10 Corpus callosumv

1.2.11 Umblical artery”

1.2.12 GrommetsY

1.2.13 Parasympatheticv nervous system
1.2.14 Choroidv

1.2.15 Karyotypev

1.2.16 Oestrogenv (1 x 16) (16)

1.3

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4
1.3.1 AonlyY

1.3.2 Both A and BY
1.3.3 Both A and BY

1.3.4 B onlyY
1.3.5 B onlyY
1.3.6 Both A ands
1.3.7 B onlyY
1.3.8 Both A and B v
1.3.9 B onlyY
1.3.10 Nonev
(1 x 10) (10)
SECTION B
QUESTION 2
2.1
2.1.1 (a) 46v (1)
(bd) 44v (1)
(c) 2v (1)
2.1.2. 23v (1)
2.1.3 Malev (1)
a2
Cell membrane
Spindle fibre
Cytoplasm
Chromatid/
Daughter
chromosome
Centriole
ANAPHASE II

OR

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5
ANY ONE OF THE FOLLOWING ARRANGEMENTS INCLUDING CORRECT LABELS

MARK ALLOCATION FOR DIAGRAM

Correct phase drawn/chromatids separating (P) 1
Correct shading of chromatids (S) 1
Correct number and size of individual chromatids/daughter 1
chromosomes (2 short and 2 long) (N)

Any TWO correct labels 2
TOTAL 5
(5)
(10)
2.3. 2.3.1 (i) Homologous chromosomesv /Bivalent (1)
(ii) Centromerev (1)
(iii) Chiasmav (1)
(iv) Chromatidy (1)
2.3.2 It holds the (two) chromatids” together (1)
2.3.3 (a) Crossing overY (1)
(b) Prophase 1”
2.3.4 Introduces variation (1)
(8)
24  2.4.1A-Urethrav (1)
B - Vas deferens” /sperm duct (1)
F - Fallopian tubev /oviduct (1)

2.4.2 (a) Protects the sperm cell against the acidic environment of the vaginav
-Increases the motility of the spermv
(Mark first ONE only) Any (1)

### Page 21

b)

(c)

2.5

2.6

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6
Place for foetus to developY

- Maintain pregnancyY

- Assist in childbirthy

- Protects the foetusv /prevents infections

- Passage forSperm cells between vagina and fallopian tubes”

(Mark first ONE only) Any

-ConnectS-thé ovaries to the uterus”
-Transports egg cells from the ovaryY

-It is the site of fertilisation’ (Mark first ONE only) Any
2.4.3 (a) Dv
(b) Gv
24.4 -Spermatogenesisv
-OogenesisY
2.4.5 -Receives the penis” during sexual intercourse

-Serves as a birth canalv

- In the fallopian tubesv
- One sperm cell makes contact with the ovum’s membranev
-The nucleus of the sperm enters the ovumv
- Then the ovum membrane cannot be penetrated by other spermsv
- The nucleus of the sperm fusesY
-With the nucleus on the ovumv
- To form a diploid zygotev Any 5
- Diploid cells in the ovary undergo mitosis”
- to form numerous follicles”
- At the onset of pubertyY
- and under the influence of FSHY
- one cell inside a follicle enlargesY and

- Of the four cells that are produced, only one survives t

A haploid ovumv Any 5

(1)

(1)

(1)
(1)
(1)
(1)

(1)
(1)

(12)

(5)

(5)
(9)

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7
QUESTION 3

3.1.
3.1.1 (i) Cerebrumv

(ii) Medull oblongataY
(iii) Eustachi n tubev

fii
3.1.2 Zin] Round window”

3.1.3 Hair cells” /Organ of Corti

3.1.4 - The pinna of the ear traps sound wavesY
- The auditory canal directs the sound waves to the tympanic membraneY
- The sound waves cause the tympanic membrane to vibratev’
- The vibrations of the tympanic membrane cause the ossicles to vibratev
- The ossicles pass the vibrations to the oval window”

- The vibration of the oval window cause pressure waves in the inner
ear /perilymph/endolymph

- The pressure waves stimulate the organ of Cortiv
- The organ of Corti converts the stimuli to nerve impulsesY
- The auditory nerve transmits the impulses

- to the cerebrum for interpretation’ Any 6

3.2

3.2.1 (a) Zygotev
(b) Morula¥
(c) PlacentaY

3.2.2 (a) Fertilisation’
(b) Implantation’

3.2.3 (a) 46v /23 pairs
(b) 23v

(1)
(1)
(1)

(2)
(1)

(6)
(12)

(1)
(1)
(1)

(1)
(1)

(1)
(1)
(7)

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3.3 3.3.1 Motor neuron” °
3.3.2 (a) Nucleus / nuclear membraneY
(b) Cytoplasm¥
(c) DendriteY
3.3.3 (a) CY —
(b) DY - lin sheathy
3.2.4 Multiple SclerosisY¥
3.3. - The receptor/ finger receives the stimulus of the heat / pain

and converts it into an impulseY

The sensory neuron carries the impulse” from the receptor

to the interneuron” connector neuron in the spinal cord

The interneuron transmits the impulse to the motor neuronY
The motor neuron carries the impulse to the effectorY / muscle
to move the finger away” from the hot pot

3.4 3.4.1 (a) Hypophysis” / Pituitary gland
(b) Adrenal gland¥

3.4.2 (a) DY - TestisY

(b) Cv -Pancreas¥
(c) Av - Hypophysisv / Pituitary gland

3.5. - The hypothalamus is stimulatedY
- and sends impulses to the blood vessels of the skin.

- Blood vessels dilateY / blood vessels become wider/vasodilation occurs.

- More blood flows to the surface of the skin.

- More heat is lost, ¥

- through radiation” from the skin.

- More blood is sent to the sweat glands. ¥

- Sweat glands become more active. VY / More sweat is released.
- Evaporation of the sweat cools (the skin).

3.6 3.6.1 (a) Suspensory ligament”
(b) IrisY

3.6.2 Protects the eyeY
3.6.3 - Ciliary muscles relaxY

Any 6

Any 6

(1)
(1)
(1)
(1)
(2)
(2)
(1)

(6)
(15)

(1)
(1)

(2)

(2)
(2)
(8)

(6)

(1)
(1)

(1)
(1)

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9

Suspensory ligaments become tautv

Tension on the lens increasesY

The lens becomes less convexv/ flattened

wel of the lens is decreasedv / light rays are bent less
Light rays are focus: ed on the retinaY

To form a clearimage

1
4
=
oO
a
©.
=
o
&
<
fo}

no}

3.7
3.7.1 hy, By iv
3.7.2 2

3.7.3 - Any individual inherits one allele~

- from each parentY
- Each child has an equal or 25% chance of having
- any blood groupv/A, B, AB or O

3.7.4- The pair of alleles on homologous chromosomes separateY

- during meiosisY / anaphase/ gamete formation, so that

- only one allele of each pair is present in the gametev / offspring
can acquire one allele from each parent

Any 4

(4)
(7)

(3)
(1)

(4)

(3)

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10

3.7.5
P, Phenotype Male x Femalev
otype XY Xx XXY¥
Meiosis
Gametes X ¥
Fertilisation Xx XX XY
X XX XY
1 mark for correct gametes
1 mark for correct genotypes
F, Phenotype *50% malesv / 50% females
P, and
Fiv
Meiosis and fertilisation’ *Compulsory 1 + Any 5
OR
P, Phenotype Male Xx Femalev
Genotype XY x XXY
Meiosis
G/gametes pe x A, mY
Fertilisation
F Genotype XX; XX: XY = XYV
1 typ: i
Phenotype *50% malesv / 50% females
P, and (6)
Fiv iar
Meiosis and fertilisation’ *Compulsory/1 + Any 5

TOTAL MARKS: [160]

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- [LIFE SCIENCES P2 GR12 QP SEPT2023 Afrikaans](https://www.hlayiso.com/library/life-sciences-p2-gr12-qp-sept2023-afrikaans/13d7c9c8-15ee-4ae8-9e7d-b86c6cb669b9) — Life Sciences · QP · 2023 · Afr
- [Life Sciences P2 (English) QP](https://www.hlayiso.com/library/life-sciences-p2-english-qp/bb04c5c6-158b-47c6-b2ca-a195e96e93ef) — Life Sciences · QP · 2023 · Eng

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- [Grade 12 past papers](https://www.hlayiso.com/grade-12/past-papers)

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