# Life Sciences Grade 12 KZN March 2021 Paper & Memo

> Grade 12 Life Sciences question paper and memo from the KZN March 2021, 15 pages. Read online or get the free PDF download.

- Page: https://www.hlayiso.com/library/life-sc-april-qp-and-memo-2021-gr12/f3586bf2-9fc9-4c4f-82ed-deda64bc0a15
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Question paper and memo
- Year: 2021
- Exam period: KZN March
- Curriculum: CAPS
- Pages: 15

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## About this document

Life Sciences · Grade 12 · KZN March · 2021. Question paper and memorandum, 15 pages. Read online or download the PDF.

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## Document text

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### Page 1

; KWAZULU-NATAL PROVINCE

EDUCATION
REPUBLIC OF SOUTH AFRICA

NATIONAL
SENIOR CERTIFICATE

GRADE 12

| ° LIFE SCIENCES :
" COMMON TEST :

" APRIL 2021 "

MARKS: 60

TIME: 1 hour

This question paper consists of 9 pages.

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Life Sciences Grade 12 Common Test April 2021

2

INSTRUCTIONS AND INFORMATION

Read the following instructions carefully before answering the questions.

7

2.

10.

ale

Answer ALL the questions.
Write ALL the answers in the ANSWER BOOK.
Start the answers to each question at the top of a NEW page.

Number the answers correctly according to the numbering system used in
this question paper.

Present your answers according to the instructions of each question.

Do ALL drawings in pencil and label them in blue or black ink.

Draw diagrams, tables or flow charts only when asked to do so.

The diagrams in this question paper are NOT necessarily drawn to scale.
Do NOT use graph paper.

You may use a non-programmable calculator, protractor and a compass.

Write neatly and legibly.

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Life Sciences Grade 12 Common Test April 2021
3

SECTION A

QUESTION 1

dai Various options are provided as possible answers to the following questions.

Choose the answer and write only the letter (A to D) next to the question
number (1.1.1. to 1.1.3) in the ANSWER BOOK, for example
1.1.4D.

1.1.1. The amniotic fluid in the amniotic egg ...

A removes waste products

B provides nutrition to the developing embryo

Cc protects the embryo against mechanical injuries
D allows gaseous exchange

1.1.2 The following combination of characteristics represent precocial
development.

(i) Offspring capable of moving around soon after hatching

(ii) Offspring with eyes closed and unable to move after hatching
(iii) Offspring capable of feeding themselves soon after hatching
(iv) Offspring nests usually on top branches of the tree

(i), (ii), (iii) and (iv)
(ii), (iii) and (iv) only
(iii) and (iv) only

(i) and (iii) only

whens e 2

1.1.3. The phase of meiosis where chromatids are pulled to the opposite
poles.

A Anaphase |

B Anaphase II

Cc Metaphase |

D Metaphase I! (3 x 2) (6)

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Life Sciences Grade 12 Common Test April 2021
4
12 Give the correct biological term for each of the following descriptions. Write
only the term next to the question number (1.2.1 to 1.2.4) in the ANSWER
BOOK.
1.2.1 The original strand of DNA used to form another strand of DNA
1.2.2 A pattern of black bars representing DNA fragments that can be
used to identify dead bodies
1.2.3 The type of RNA that attaches to the ribosome during protein
synthesis
1.2.4 Type of fertilisation where a sperm cell fuses with an ovum outside

the female body

(4x1)

1.3 Indicate whether each of the descriptions in COLUMN | applies to A ONLY, B
ONLY, BOTH A AND B or NONE of the items in COLUMN II. Write A only, B
only, both A and B, or none next to the question number (1.3.1 to 1.3.3) in

the ANSWER BOOK.
COLUMN! COLUMN II
1.3.1 | Chromosomes arranged along ithe | A: Metaphase |
equator in a single row B: Metaphase II
1.3.2 | Embryo is nourished with yolk A: Ovipary
found in the egg B: _Vivipary
1.3.3 | Chromosome number in gametes | A: Haploid
B: Diploid

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(3 x 2)

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(4)

(6)

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Life Sciences

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Grade 12 Common Test April 2021

5

14 The diagram below represents a part of the structure of a nucleic acid.

1.441
1.4.2

1.4.3

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Identify the molecule above.
Give an observable reason for your answer in QUESTION 1.4.1.

Name TWO locations where the above molecule is found in animal
cells.

TOTAL SECTION A:

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(1)

(2)
(4)

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Grade 12

Life Sciences

SECTION B

QUESTION 2

Common Test April 2021

24 Albumin is a single chain globular protein made up of 585 amino acids. A
small section of the DNA sequence coding for the formation of albumin is
shown below.

TABLE A
1 2 3 4 5 6
TGC GAG | GTG GAT AAG CGT

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Write down the anticodon of the DNA base triplet 6.

Describe the role of tRNA in protein synthesis.

How many nitrogenous bases are found in the mRNA molecule
coding for the formation of the albumin protein? Show ALL working.

The table below shows the base triplets in MRNA that code for

different amino acids found in albumin.

TABLE B
AMINO ACID mRNA
Arginine GCA

| Cysteine ACG
Lysine UUC
Aspartic acid CUA
Histidine CAC
Glutamic acid CUC

Using TABLE B above, name the amino acid coded for by the DNA

base triplet as shown in TABLE A:

Describe the process of transcription.

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Life Sciences Grade 12 Common Test April 2021
7
22 The diagrams below represent cells in a phase of meiosis.
2.2.1 Which phase of meiosis is represented by the diagrams above? (1)
2.2.2 State TWO processes that resulted in the appearance of
chromosomes in the diagram above. (2)
2.2.3 Draw a labelled diagram to show the cell before the phase shown in
the diagrams above. (4)
(7)
[20]

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Life Sciences Grade 12 Common Test April 2021
8

QUESTION 3

3.1 An investigation was conducted to determine the effect of high amounts of

progesterone on FSH production in human females.

The procedure was as follows:

20 healthy women who are not pregnant were used.

The women are all of the same age.

They were divided into 2 groups (Groups A and B).

Each group had 10 participants.

Their FSH levels were determined and recorded before the investigation.
Group A was injected with the progesterone injection which takes 13
weeks to metabolise in the body.

Group B was not treated with the progesterone injection.

Both groups were exposed to the same environmental conditions for 3
months.

Their FSH levels were recorded on day 3 of every menstrual cycle for the
duration of the investigation.

The average FSH levels of both groups was calculated.

The results are shown in the table below.

GROUP AVERAGE FSH LEVEL IN THE
BLOOD (mIU/mL)
7 A 3.4
B 9.5

3.1.1. Identify the independent variable in the investigation.

3.1.2. Name TWO factors that were kept constant during the selection of

participants.

3.1.3. Explain why Group B was included in the investigation.

3.1.4 Explain why the average FSH level in the blood in group A is low.

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(1)

(2)

(2)
(7)

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Life Sciences Grade 12 Common Test April 2021
9
3.2 The table below shows the testosterone levels in the blood of male in different
ages.
AGE (YEARS) TESTOSTERONE LEVELS
(ng/dl)

35-44 667

45-54 606

55-64 562

65-74 523

75-84 470

3.2.1. Name the part of the male reproductive system that:
(a) Secretes testosterone
(b) Stores sperm cells

3.2.2 According to the table above, what is the testosterone level in a 57
year old male?

3.2.3 Describe the relationship between the age and the testosterone
levels shown in the table above.

3.2.4 Explain what will be the effect on reproduction if the testosterone
levels of 35 year old male is 0 ng/di?

3.3 Describe the process of oogenesis.

TOTAL SECTION B:

GRAND TOTAL:

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(1)
(1)

(1)
(2)
(2)
(7)

(6)
[20]

40

60

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                     NATIONAL
                SENIOR CERTIFICATE

                       GRADE 12

                          LIFE SCIENCES

                   APRIL 2021 COMMON TEST

                      MARKING GUIDELINE

MARKS: 60

             This marking guideline consists of 6 pages.

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Life Sciences                        Grade 12 Memorandum                          March 2021
                                              2

 PRINCIPLES RELATED TO MARKING LIFE SCIENCES

 1.      If more information than marks allocated is given
         Stop marking when maximum marks is reached and put a wavy line and 'max' in the
         right-hand margin.

 2.      If, for example, three reasons are required and five are given
         Mark the first three irrespective of whether all or some are correct/incorrect.

 3.      If whole process is given when only a part of it is required
         Read all and credit the relevant part.

 4.     If comparisons are asked for, but descriptions are given
        Accept if the differences/similarities are clear.

 5.      If tabulation is required, but paragraphs are given
         Candidates will lose marks for not tabulating.

 6.     If diagrams are given with annotations when descriptions are required
        Candidates will lose marks.

 7.      If flow charts are given instead of descriptions
         Candidates will lose marks.

 8.      If sequence is muddled and links do not make sense
         Where sequence and links are correct, credit. Where sequence and links are
         incorrect, do not credit. If sequence and links become correct again, resume credit.

 9.      Non-recognised abbreviations
         Accept if first defined in answer. If not defined, do not credit the unrecognised
         abbreviation, but credit the rest of the answer if correct.

 10.     Wrong numbering
         If answer fits into the correct sequence of questions, but the wrong number is given,
         it is acceptable.

 11.     If language used changes the intended meaning
         Do not accept.

 12.     Spelling errors
         If recognisable, accept the answer, provided it does not mean something else in Life
         Sciences or if it is out of context.

 13.     If common names are given in terminology
         Accept, provided it was accepted at the national memo discussion meeting.

 14.     If only the letter is asked for, but only the name is given (and vice versa)
         Do not credit.

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Life Sciences                       Grade 12 Memorandum                             March 2021
                                             3

 15.     If units are not given in measurements
         Candidates will lose marks. Memorandum will allocate marks for units separately.

 16.   Be sensitive to the sense of an answer, which may be stated in a different way.

 17.   Caption
       All illustrations (diagrams, graphs, tables, etc.) must have a caption.

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Life Sciences                        Grade 12 Memorandum                     March 2021
                                             4

 SECTION A

 QUESTION 1

 1.1    1.1.1    C
        1.1.2    D
        1.1.3    B
                                                                                  (3 x 2)    (6)

 1.2    1.2.1    Template
        1.2.2    DNA profile
        1.2.3    mRNA
        1.2.4    External fertilisation
                                                                                  (4 x 1)    (4)

 1.3    1.3.1    B only
        1.3.2    A only
        1.3.3    A only
                                                                                  (3 x 2)    (6)

 1.4    1.4.1    DNA                                                                        (1)
        1.4.2    -Double stranded
                 -Weak hydrogen bonds                                                Any     (1)
        1.4.3    - Nucleus
                 - Mitochondrion                                                            (2)
                  Mark first TWO only                                                        (4)

                                                                  TOTAL SECTION A:           20

 SECTION B

 QUESTION 2

 2.1    2.1.1    CGU                                                                        (1)

        2.1.2    Brings required amino acids to the ribosomes to form the required
                 proteins                                                                    (2)

        2.1.3    585 x 3 = 1755                                                            (2)

        2.1.4    (a) Cysteine                                                               (1)
                 (b) Aspartic acid                                                          (1)

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 Life Sciences                     Grade 12 Memorandum                       March 2021
                                            5

        2.1.5    - The double helix DNA unwinds
                 - The double-stranded DNA unzips/weak hydrogen bonds break
                 - to form two separate strands
                 - One strand is used as a template
                 - to form mRNA
                 - using free RNA nucleotides from the nucleoplasm
                 - The mRNA is complementary to the DNA
                 - mRNA now has the coded message for protein synthesis            Any        (6)
                                                                                               (13)

 2.2    2.2.1    Telophase II                                                               (1)

        2.2.2    - Crossing over
                 - Random arrangement                                                       (2)
                 (Mark first TWO only)

        2.2.3    Anaphase II
                                                          Centrosome/centriole

                                                          Spindle fibre

                                                          Chromatid

                                                          Cell membrane

                                                         Centromere

                 Marking criteria:
                  Caption                            1
                  Correct type of diagram
                  with the correct
                  shading and correct
                  position (4 chromatids
                  arranged correctly)                1
                  Any two correct labels             2
                                                                                             (4)
                                                                                             (7)

                                                                                             [20]

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  Life Sciences                      Grade 12 Memorandum                          March 2021
                                              6

 QUESTION 3

 3.1    3.1.1     High amounts of progesterone                                                   (1)

        3.1.2     - All healthy females
                  - No pregnant females
                  - Age                                                                 Any      (2)
                  (Mark first TWO only)

        3.1.3     - To serve as control
                  - so that it can be compared with group A
                  - It shows that progesterone is the only factor that affects the results/
                    improves validity of the investigation                                Any     (2)

        3.1.4     - High amounts of progesteronein the blood
                  - inhibited FSH production                                                     (2)
                                                                                                  (7)

 3.2    3.2.1     (a) Testes                                                                     (1)
                  (b) Epididymis                                                                 (1)

        3.2.2     562                                                                            (1)

        3.2.3     As the age increases, the testosterone level in the blood of males
                  decreases                                                                     (2)

        3.2.4     - No spermatogenesis will occur
                  - therefore, semen produced will have no sperm cells
                  - to fertilise the ovum                                              Any       (2)
                                                                                                  (7)

 3.3       - Under the influence of FSH
           - diploid cells/germinal epithelial cells
           - in the ovary
           - undergo mitosis
           - to form numerous follicles
           - One cell inside a follicle enlarges and undergoes meiosis
           - Of the four cells that are produced, only one survives to form a mature,
             haploid ovum                                                            Any         (6)
                                                                                                  [20]

                                                                      TOTAL SECTION B:            40

                                                                           GRAND TOTAL:           60

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