# Life Sciences Grade 12 Eastern Cape June 2024 Memo (English)

> Grade 12 Life Sciences memorandum from the Eastern Cape June Exam 2024 (English), 9 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/life-sciences-gr12-memo-june-2024-english/af588ff5-82a5-43cf-b2be-01e0c0c3cb24
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Language: English
- Document type: Memorandum
- Year: 2024
- Exam period: Eastern Cape June Exam
- Curriculum: CAPS
- Pages: 9

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## About this document

Life Sciences · Grade 12 · Eastern Cape June Exam · 2024 · English. Memorandum, 9 pages. Read online or download the PDF.

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## Document text

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### Page 1

NATIONAL
                 SENIOR CERTIFICATE

                         GRADE 12

                        JUNE 2024

                 LIFE SCIENCES
               MARKING GUIDELINE

MARKS:   150

               This marking guideline consists of 9 pages.

### Page 2

2                                LIFE SCIENCES                                     (EC/JUNE 2024)

PRINCIPLES RELATED TO MARKING LIFE SCIENCES

1.    If more information than marks allocated is given
      Stop marking when maximum marks are reached and put a wavy line and ‘max.’
      in the right-hand margin.

2.    If, for example, three reasons are required and five are given
      Mark the first three irrespective of whether all or some are correct/incorrect.

3.    If whole process is given when only a part of it is required
      Read all and credit the relevant part.

4.    If comparisons are asked for but descriptions are given
      Accept if the differences/similarities are clear.

5.    If tabulation is required but paragraphs are given
      Candidates will lose marks for not tabulating.

6.    If diagrams are given with annotations when descriptions are required
      Candidates will lose marks.

7.    If flow charts are given instead of descriptions
      Candidates will lose marks.

8.    If sequence is muddled and links do not make sense
      Where sequence and links are correct, credit. Where sequence and links are
      incorrect, do not credit. If sequence and links become correct again, resume
      credit.

9.    Non-recognised abbreviations
      Accept if first defined in answer. If not defined, do not credit the unrecognised
      abbreviation but credit the rest of the answer if correct.

10.   Wrong numbering
      If answer fits into the correct sequence of questions but the wrong number is
      given, it is acceptable.

11.   If language used changes the intended meaning
      Do not accept.

12.   Spelling errors
      If recognisable, accept the answer, provided it does not mean something else
      in Life Sciences or if it is out of context.

13.   If common names are given in terminology
      Accept, provided it was accepted at the provincial marking guideline discussion
      meeting.

14.   If only the letter is asked for but only the name is given (and vice versa)
      Do not credit.

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### Page 3

(EC/JUNE 2024)                                  LIFE SCIENCES                                        3

15.    If units are not given in measurements
       Candidates will lose marks. Marking guideline will allocate marks for units
       separately.

16.    Be sensitive to the sense of an answer, which may be stated in a different
       way.

17.    Caption
       All illustrations (diagrams, graphs, tables, etc.) must have a caption.

18.    Code-switching of official languages (terms and concepts)
       A single word or two that appear(s) in any official language other than the
       learners' assessment language used to the greatest extent in his/her answers
       should be credited if it is correct. A marker that is proficient in the relevant official
       language should be consulted. This is applicable to all official languages.

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### Page 4

4                                LIFE SCIENCES                     (EC/JUNE 2024)

SECTION A
QUESTION 1
1.1    1.1.1     C ✓✓
       1.1.2     A ✓✓
       1.1.3     D ✓✓
       1.1.4     A ✓✓
       1.1.5     D ✓✓
       1.1.6     D ✓✓
       1.1.7     C ✓✓
       1.1.8     D ✓✓
       1.1.9     B ✓✓
       1.1.10    C ✓✓                                           (20 x 1)     (20)

1.2    1.2.1     Haemophilia ✓
       1.2.2     Anaphase 1 ✓
       1.2.3     Non-disjunction ✓
       1.2.4     Chromosome ✓
       1.2.5     Centriole ✓/centrosome
       1.2.6     Multiple sclerosis ✓
       1.2.7     Short-sightedness ✓/Myopia
       1.2.8     Auditory nerve ✓
       1.2.9     Oestrogen ✓
       1.2.10    Amniotic ✓ fluid                               (10 x 1)     (10)

1.3    1.3.1     A only ✓✓
       1.3.2     B only ✓✓
       1.3.3     B only ✓✓                                                     (6)
       1.4.1     (a)    E✓                                                     (1)
                 (b)    A✓                                                     (1)
                 (c)    C✓                                                     (1)

1.4    1.4.2     F ✓ motor neuron ✓/efferent neuron                           (2)

       1.4.3     D to E ✓                                                     (1)

1.5    1.5.1     (a)    A ✓ ciliary muscle ✓                                   (2)
                 (b)    C ✓ iris ✓                                             (2)
                 (c)    D ✓ cornea ✓                                           (2)

       1.5.2     Accommodation ✓                                               (1)

       1.5.3     (Diagram) 2 ✓                                                 (1)

                                                      TOTAL SECTION A:         50

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### Page 5

(EC/JUNE 2024)                                  LIFE SCIENCES                                  5

QUESTION 2

2.1 2.1.1        (James) Watson ✓                                                              (1)

      2.1.2      double helix ✓                                                                (1)

      2.1.3      Sample 1 ✓                                                                    (1)

      2.1.4      •     In Sample 1 the number of A/adenine equals the number of T/thymine
                       and G/guanine is equal to C/cytosine ✓✓/In a DNA molecule A/G and
                       T/C are complementary pairs and are therefore equal.
                                                       OR
                 •     There is no U/uracil in sample 1 ✓✓/DNA does not contain U/uracil.      (2)

      2.1.5

                 Phosphate

                 (Deoxyribose) Sugar
                                             Nitrogenous base

                 Marking guideline for drawing a nucleotide:

                                         Criteria                       Mark allocation
                     Phosphate diagram and labelled in correct
                     position                                               1 mark
                     Sugar diagram and labelled in correct position         1 mark
                     Nitrogenous base diagram and labelled in correct
                     position                                               1 mark             (3)

      2.1.6                   DNA                            RNA
                  Has thymine base ✓            Has uracil base ✓
                  Deoxyribose sugar ✓           Ribose sugar ✓
                 Table ✓ + any ONE difference ✓✓                                               (3)

      2.2.1      A-U-G-A-G-C-G-U-A ✓✓                                                          (2)

      2.2.2      •     The (double helix) DNA unwinds ✓
                 •     The (double-stranded) DNA unzips ✓/weak hydrogen bonds break to
                       form two separate strands.
                 •     One strand is used as a template ✓
                 •     to form mRNA ✓
                 •     using free floating RNA nucleotides ✓ in the nucleus
                 •     which joins to their complimentary bases ✓ / A-U and C-G (Any 4 x 1)    (4)
      2.2.3      C was replaced with G in DNA …
                 • Therefore, the mRNA will change from G to C ✓
                 • The tRNA will change from C to G ✓
                 • This would code for a different amino acid ✓
                 • Which would code for the protein which breaks down DDT ✓                    (4)
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### Page 6

6                                   LIFE SCIENCES                                   (EC/JUNE 2024)

2.3 2.3.1     FSH ✓ / oestrogen                                                                 (1)
     2.3.2    •  FSH – follicle starts to develop ✓/grow
                                                   OR
              • Oestrogen – endometrium starts to thicken ✓
              (NB: Reason for hormone must correspond to hormone given in 2.3.1)                (1)
     2.3.3    •      The corpus luteum does not degenerate ✓ after day 28
              •      and continues to produce progesterone ✓
              •      which maintains the endometrium after day 28 ✓/ endometrium does
                     not degenerate                                                             (3)
     2.3.4    •      The zygote ✓
              •      divides by mitosis ✓
              •      to form a (solid) ball of cells ✓
              •      called a morula ✓
              •      which then develops into a hollow ball of cells ✓
              •      called the blastula ✓ / blastocyst                                         (6)
     2.3.5    •      LH ✓ would be monitored.
              •      Ovulation takes place when LH peaks ✓ /reaches maximum.
              •      therefore, the ovum would be available for fertilisation ✓                 (3)

2.4 2.4.1     Genetic engineering ✓/ Recombinant DNA                                            (1)

     2.4.2    •      There will be no nuts as food for humans ✓/ no timber
              •      Which will reduce the number of people ✓
                                                       OR
              •      No habitat for wildlife ✓/ Fruit as food for wildlife
              •      Which would reduce the number of animals ✓                                 (2)

     2.4.3    •      A plasmid is removed from the bacteria ✓
              •      it is spliced open ✓ using an enzyme
              •      the desired gene is extracted ✓
              •      and inserted into the plasmid ✓
              •      the plasmid is placed back into the bacteria ✓                             (5)

     2.4.4    • They can become invasive ✓ because they are no longer.
              • controlled by the disease ✓                                                     (2)

2.4 2.5.1     Metaphase 1 ✓                                                                     (1)

     2.5.2    •      Spindle fibre shorten ✓
              •      Centromere splits separating each chromosome into two ✓
              •      daughter chromosomes are pulled to opposite poles ✓                        (3)

     2.5.3    ovaries ✓                                                                         (1)
                                                                                               [50]

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### Page 7

(EC/JUNE 2024)                                   LIFE SCIENCES                                             7

QUESTION 3

3.1   3.1.1      Pedigree diagram ✓                                                                       (1)

      3.1.2      Mutation/gene for disease found on the X/sex chromosomes/
                 gonosomes ✓                                                                              (1)

      3.1.3      4✓                                                                                       (1)

      3.1.4      recessive ✓                                                                              (1)

      3.1.5      •     Individuals 2 / 7 / 10 do not have Menkes syndrome ✓
                 •     however, they (2 / 7 / 10) carry the allele ✓
                 •     because they have a child 5 /13 / 15 who has Menkes syndrome ✓                     (3)

      3.1.6      (a)      XR Xr ✓                                                                         (1)
                 (b)      Xr Y ✓                                                                          (1)

      3.1.7       P1                Phenotype   Male with Menkes                    Normal Female 
                                                                                x
                                                Syndrome
                                    Genotype       Xr Y                         x    XRXR    
                  Meiosis
                                    G/gametes    Xr     ,      Y            x       XR   , XR 

                  Fertilisation

                  F1                Genotype          XRXr :       XRXr : XRY : XRY 

                                    Phenotype   2 Normal females: 2 Normal males 
                                                *0% chance for the next child to have
                                                Menkes syndrome 
                  P1 and F1 
                  Meiosis and fertilisation 
                                                                           *1 compulsory + Any 5
                                                   OR
                  P1                Phenotype  Male with Menkes                     Normal Female 
                                                                                x
                                                  Syndrome
                                    Genotype          Xr Y                      x    XRXR    
                                           G/gametes       Xr                         Y
                  Meiosis                        XR                XR Xr             XR Y
                                                 XR                XR Xr             XR Y
                  Fertilisation           1 mark for correct gametes 
                                          1 mark for correct genotypes 
                                    Phenotype 2 Normal females: 2 Normal males 
                                                *0% chance for the next child to have
                                                Menkes syndrome 
                  P1 and F1 
                  Meiosis and fertilisation 
                                                                           *1 compulsory + Any 5          (6)

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### Page 8

8                                    LIFE SCIENCES                                     (EC/JUNE 2024)

       3.1.8    •     Males only have 1 X chromosome ✓ / XY
                •     If they carry the Menkes syndrome allele on the X chromosome
                      they will have the disease ✓                                                 (2)

3.2    3.2.1    (a)      Eustachian tube ✓                                                         (1)
                (b)      Round window ✓                                                            (1)

       3.2.2    (a)      G ✓ – auditory canal ✓                                                    (2)
                (b)      B ✓ ‒ semi-circular canals ✓                                              (2)

       3.2.3    (a)      •   The fluid in the middle ear prevents the ossicles
                             vibrating freely ✓*
                         •   Therefore less/no vibrations are transmitted to the oval
                             window ✓
                         •   Less/no pressure wave are set up in the inner ear ✓
                         •   The organ or corti is stimulated less ✓/not stimulated.
                         •   Impulse is not sent on the auditory nerve to the cerebrum to
                             be interpreted ✓
                                                                (*1 Compulsory + Any 3)            (4)

                (b)      Tympanic membrane ✓/ear drum                                              (1)

3.3    3.3.1    (a)      cerebellum ✓                                                              (1)
                (b)      Medulla oblongata ✓                                                       (1)

       3.3.2    Connects/allows communication           between   the   left   and     right
                hemisphere of the cerebrum ✓✓                                                      (2)

       3.3.3    A ✓ – cerebrum ✓                                                                   (2)

       3.3.4    •     The cerebellum is damaged ✓
                •     Due to no coordination of the voluntary movements ✓ by the
                      cerebellum
                •     The cerebellum is responsible or balance and coordination ✓                  (3)

3.4    3.4.1    to gain muscle strength, shape and performance ✓                                   (1)

       3.4.2    (a)      Male fertility ✓                                                          (1)

                (b)      AAS ✓ (not effect of AAS)                                                 (1)

       3.4.3    same age ✓ of males
                same amount of AAS ✓ taken                                                         (2)

       3.4.4    •     Acts as a control ✓
                •     To show the results obtained by Group B ✓
                •     Are caused by the AAS ✓
                •     And not by the exercise ✓                                (Any 3 x 1)         (3)

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### Page 9

(EC/JUNE 2024)                              LIFE SCIENCES                                   9

       3.4.5     The higher the level of testosterone ✓ the higher the sperm count ✓
                 Testosterone stimulates the production of sperm ✓                          (3)

       3.4.6     High temperatures ✓ would cause sperm to not mature ✓/be deformed         (2)
                                                                                          [50]

                                                                TOTAL SECTION B:           100
                                                                   GRAND TOTAL:            150

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