# Life Sciences Grade 12 P1 NSC Supplementary 2012 QP (Eng)

> Grade 12 Life Sciences Paper 1 question paper from the NSC Supplementary 2012 (English), 15 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/life-sciences-p1-feb-march-2012-eng-version-1/28232730-3fce-4516-8781-1c83319a5533
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Question paper
- Year: 2012
- Exam period: NSC Supplementary
- Paper: 1
- Curriculum: CAPS
- Pages: 15

Breadcrumbs: [Home](https://www.hlayiso.com/) › [Library](https://www.hlayiso.com/library) › [Grade 12](https://www.hlayiso.com/library/grade-12) › [Life Sciences](https://www.hlayiso.com/library/grade-12/life-sciences) › [Life Sciences Grade 12 P1 NSC Supplementary 2012 QP (Eng)](https://www.hlayiso.com/library/life-sciences-p1-feb-march-2012-eng-version-1/28232730-3fce-4516-8781-1c83319a5533)

## About this document

Life Sciences · Grade 12 · NSC Supplementary · 2012. Question paper, 15 pages. Read online or download the PDF.

Read it free online on the page above; download the PDF from there.

## Document text

Text extracted from the PDF. Layout, diagrams and tables may not survive extraction.

### Page 1

Downloaded from hlayiso.com

                                   NATIONAL
                              SENIOR CERTIFICATE

                                    GRADE 12

                                 LIFE SCIENCES P1

         VERSION 1 (NEW CONTENT) FOR FULL-TIME CANDIDATES

                             FEBRUARY/MARCH 2012

MARKS: 150

TIME: 2½ hours

                       This question paper consists of 15 pages.

Copyright reserved                                                 Please turn over

### Page 2

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)      2                             DBE/Feb.–Mar. 2012
                                             NSC

INSTRUCTIONS AND INFORMATION

Read the following instructions carefully before answering the questions.

1.         Answer ALL the questions.

2.         Write ALL the answers in your ANSWER BOOK.

3.         Start the answers to each question at the top of a NEW page.

4.         Number the answers correctly according to the numbering system used in this
           question paper.

5.         Present your answers according to the instructions of each question.

6.         ALL drawings should be done in pencil and labelled in blue or black ink.

7.         Draw diagrams or flow charts only when asked to do so.

8.         The diagrams in this question paper are NOT necessarily drawn to scale.

9.         Do NOT use graph paper.

10.        You may use a non-programmable calculator, protractor and a compass.

11.        Write neatly and legibly.

Copyright reserved                                                             Please turn over

### Page 3

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)         3                            DBE/Feb.–Mar. 2012
                                                NSC

SECTION A

QUESTION 1

1.1        Various options are provided as possible answers to the following questions.
           Choose the correct answer and write only the letter (A to D) next to the
           question number (1.1.1 to 1.1.10) in your ANSWER BOOK, for example
           1.1.11 D.

           1.1.1      Genes only code for …

                      A      starch.
                      B      proteins.
                      C      glucose.
                      D      fats.

          1.1.2       The wings of a butterfly and the wings of a bird are examples of …

                      A     homologous structures.
                      B     vestigial structures.
                      C     analogous structures.
                      D     common ancestry.

          1.1.3       Which ONE of the following is an acceptable explanation based on
                      Darwin's theory of evolution?

                      A     Humans evolved from apes
                      B     A mother who had her appendix removed will give birth to
                            children without an appendix
                      C     An increasing number of TB-causing bacteria are resistant to
                            antibiotics because those that are resistant are able to survive
                            and reproduce
                      D     Giraffes have long necks because the previous generation
                            stretched their necks to reach the leaves in tall trees

           1.1.4        As DNA was extracted from cells of E. coli it was analysed for its
                        nitrogenous base composition. It was found that 38% of the bases
                        are cytosine. What percentage of the bases are adenine?

                        A    12
                        B    24
                        C    38
                        D    62

Copyright reserved                                                               Please turn over

### Page 4

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)          4                              DBE/Feb.–Mar. 2012
                                                 NSC

           1.1.5        Below is a list of fossils discovered in South Africa.

                        1.   Mrs Ples
                        2.   Taung child
                        3.   Little foot
                        4.   Karabo

                        Which of the fossils above are classified in the genus
                        Australopithecus?

                        A    1, 2 and 3 only
                        B    1, 2, 3 and 4
                        C    2, 3 and 4 only
                        D    1, 3 and 4 only

           1.1.6        A mother has blood group B and a father blood group O. They
                        have three children and an adopted child. The blood groups of the
                        children are represented in the table below.

                               CHILDREN                BLOOD GROUPS
                                 Sindy                      AB
                                Nobubele                     B
                                 Kenny                      O
                                Gabriele                     B

                      Which child is adopted?

                        A    Sindy
                        B    Nobubele
                        C    Gabriele
                        D    Kenny

Copyright reserved                                                                  Please turn over

### Page 5

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)           5                       DBE/Feb.–Mar. 2012
                                                  NSC

          QUESTIONS 1.1.7 to 1.1.9 are based on the diagrammatic
          representation below of a part of two different nucleic acid molecules
          found in the cells of organisms during a stage in the process of protein
          synthesis.

                                              A

                                              G

                                                    U

                                                    C

                                              T

                                     Molecule 1         Molecule 2

           1.1.7        The diagram above illustrates the process of ...

                        A    replication.
                        B    transcription.
                        C    translation.
                        D    mutation.

           1.1.8        The process illustrated above occurs in the …

                        A    cytoplasm.
                        B    centrosome.
                        C    ribosome.
                        D    nucleus.

Copyright reserved                                                            Please turn over

### Page 6

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)          6                              DBE/Feb.–Mar. 2012
                                                 NSC

           1.1.9        An observable difference between molecule 1 and molecule 2 is
                        that …

                        A    molecule 1 is double stranded and molecule 2 is single
                             stranded.
                        B    molecule 1 contains deoxyribose sugars and molecule 2
                             contains ribose sugars.
                        C    molecule 1 has thymine and molecule 2 has uracil.
                        D    molecule 1 is longer than molecule 2.

           1.1.10       The mRNA sequence from a portion of a DNA template GATCAA
                        is …

                        A    CTAGTT.
                        B    CUAGUU.
                        C    AGCTGG.
                        D    AGCUGG.                                                    (10 x 2)       (20)

1.2        Give the correct biological term for each of the following descriptions. Write
           only the term next to the question number (1.2.1 to 1.2.9) in your ANSWER
           BOOK.

           1.2.1        An allele that is not shown/expressed in the phenotype when found
                        in the heterozygous condition

           1.2.2        Chromosomes other than the sex chromosomes

           1.2.3        The production      of   genetically    identical   organisms     using
                        biotechnology

           1.2.4        More than two haploid sets of chromosomes found in the cells of
                        an organism

           1.2.5        The transfer of a selected gene from one organism to another

           1.2.6        A variable that is manipulated during an investigation

           1.2.7        All the genes of a particular species

           1.2.8        The position of a gene on a chromosome

           1.2.9        The complete disappearance of a species from Earth                             (9)

Copyright reserved                                                                  Please turn over

### Page 7

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)        7                              DBE/Feb.–Mar. 2012
                                               NSC

1.3       Indicate whether each of the statements in COLUMN I applies to
          A ONLY, B ONLY, BOTH A AND B or NONE of the items in
          COLUMN II. Write A only, B only, both A and B, or none next to the
          question number (1.3.1 to 1.3.6) in the ANSWER BOOK.

                                COLUMN I                       COLUMN II
         1.3.1       The study of the past and        A: Palaeontology
                     present distribution of          B: Biogeography
                     individual species as evidence
                     for evolution
         1.3.2       The evidence used to support     A: Y chromosome
                     the 'Out of Africa' hypothesis   B: Mitochondrial DNA
                     by tracing the maternal
                     lineage
         1.3.3       Inheritance of the disorder      A: Colour blindness
                     linked to a sex chromosome       B: Sickle cell anaemia
         1.3.4       First Homo species to have       A: Homo habilis
                     migrated out of Africa           B: Homo sapiens
         1.3.5       Natural selection as an          A: Alfred Wallace
                     explanation for evolution        B: Charles Darwin
         1.3.6       Organisms have an                A: Lamarck
                     inherent/internal drive to       B: Wallace
                     change
                                                                                       (6 x 2)       (12)

Copyright reserved                                                                Please turn over

### Page 8

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)         8                           DBE/Feb.–Mar. 2012
                                                NSC

1.4       The diagram below represents a cladogram (phylogenetic tree)
          showing primate evolution. The letters, A to E, indicate the
          characteristics which are shared by the different species of primates
          which follow the letter. The point where various species of primates
          differ from each other is indicated by the branching-off/split into new
          species.

              Capuchin         Vervet
                                            Rhesus       Gibbon
              monkey           monkey
                                            monkey
                                                                    Chimpanzee       Human

                                                                                 E
                                                            D
                                                C
                          B
          A

                              Cladogram showing primate evolution

           1.4.1         Which LETTER represents a common characteristic of all
                         primates?                                                                  (1)

           1.4.2         List THREE structural characteristics represented by the LETTER
                         named in QUESTION 1.4.1.                                                   (3)

           1.4.3         Which organism is most similar to the chimpanzee?                          (1)

           1.4.4         Name any TWO structural characteristics of the skull that make the
                         organism named in QUESTION 1.4.3 different from the
                         chimpanzee.                                                                (2)

           1.4.5         Write down the names of the organisms that display the
                         characteristic C but not characteristics D and E.                          (2)
                                                                                                    (9)

                                                                      TOTAL SECTION A:              50

Copyright reserved                                                               Please turn over

### Page 9

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)              9                    DBE/Feb.–Mar. 2012
                                                     NSC

SECTION B
QUESTION 2

2.1        Study the diagrams below which illustrate some phases of meiosis I.

                            Diagram 1                      Diagram 2

                                                 A

                                                                       B
                                              Diagram 3

                                           PHASES OF MEIOSIS

          2.1.1       Label parts A and B respectively.                                          (2)

          2.1.2       The diagrams above are not placed in the correct sequence. Use
                      the diagram numbers to write down the correct sequence in which
                      part of the process of meiosis I takes place.                              (2)

          2.1.3       Give TWO observable reasons why the phases in the diagram are
                      part of meiosis I.                                                         (2)
                                                                                                 (6)

Copyright reserved                                                            Please turn over

### Page 10

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)                 10                       DBE/Feb.–Mar. 2012
                                                        NSC

2.2        The karyotype below is that of a male person with a genetic disorder called
           Klinefelter syndrome.

               1                 2             3                         4         5

               6             7             8            9          10        11    12

              13        14           15                             16       17    18

              19          20                       21         22                  23

                       A karyotype of a male with Klinefelter syndrome

           2.2.1        State ONE visible difference between the karyotype above and the
                        karyotype of a normal male.                                                       (2)

           2.2.2        Use your knowledge of meiosis to explain how Klinefelter
                        syndrome could have resulted.                                                     (6)
                                                                                                          (8)

2.3        A boy's mother had a patch of white hair called a 'white forelock' which is
           caused by a dominant allele H. The mother is heterozygous for this trait. His
           father does not have a 'white forelock'. The symbol for the recessive allele
           is h.

           Represent a genetic cross to determine the possible genotypes and
           phenotypes of the children.                                                                    (6)

Copyright reserved                                                                     Please turn over

### Page 11

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)           11                    DBE/Feb.–Mar. 2012
                                                  NSC

2.4       Study the pedigree diagram below which shows the inheritance of
          flower colour in a certain plant over three generations.

          Use the following symbols for the contrasting alleles:

          W – for white colour
          R – for red colour

                                           A

                                                              B

                                                         C

         Pedigree diagram showing inheritance of flower colour in a certain
                        type of plant over three generations

         KEY:

                              White flower colour

                              Red flower colour

                              Flower with equal distribution of white
                              and red colour

           2.4.1        Name the type of inheritance shown in the pedigree diagram
                        above.                                                                 (1)

           2.4.2        Explain your answer to QUESTION 2.4.1.                                 (3)

           2.4.3        Use the symbols R and W and write down the genotypes of each of
                        the following flowers:

                       (a)    A
                       (b)    B
                       (c)    C                                                  (3 x 2)       (6)
                                                                                               (10)
                                                                                               [30]

Copyright reserved                                                          Please turn over

### Page 12

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)         12                            DBE/Feb.–Mar. 2012
                                                NSC

QUESTION 3

3.1        A young couple wants to have a child, but they are aware of a serious genetic
           disorder in one of their families that could be carried through to their offspring.

           In this case state:

           3.1.1        ONE advantage of DNA testing                                                 (1)

           3.1.2        THREE benefits of genetic counselling                                        (3)
                                                                                                     (4)

3.2        State TWO ways in which DNA profiling can be used to our advantage.                       (2)

3.3        Tabulate the structural differences between australopithecines, such as
           Australopithecus sediba, and humans by referring to the size of the skeleton,
           cranium and the chin.                                                                     (7)

3.4        Read the passage below and then answer the questions that follow.

           All types of domestic dogs are capable of interbreeding to produce puppies,
           which will eventually be capable of interbreeding with any other domestic dog.

           The first dog evolved from a population of wolves. It is thought that wolves
           that were tamer than usual 'adopted' humans in order to scavenge food from
           refuse dumps near human settlements.

           Although wolves look very similar to some breeds of domestic dogs, wolves
           and domestic dogs cannot interbreed.

           3.4.1        Explain why all breeds of domestic dogs belong to the same
                        species.                                                                     (2)

           3.4.2        Describe how a population of wolves may have undergone
                        speciation to form the first population of dogs.                             (6)

           3.4.3        Describe how artificial selection led to different breeds of domestic
                        dogs.                                                                        (2)
                                                                                                     (10)

Copyright reserved                                                                Please turn over

### Page 13

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)         13                           DBE/Feb.–Mar. 2012
                                                NSC

3.5        A group of learners from a school decided to do an investigation, using
           scientific literature, on the evidence presented by fossils to support the theory
           of evolution.

           They formulated the following hypothesis:

           'First appearance of fossils of single-cell/simple organisms are found in
           the oldest layers of rock'

           A summary of their research from the scientific literature is shown in the table
           below.

      ERA              GEOLOGICAL               MAJOR EVENTS IN THE HISTORY OF LIFE
                        TIMESCALE
                     (MILLION YEARS
                           AGO)
 Cenozoic          65–present                  Appearance of Homo species
                                               Flowering plants, insects, birds and mammals
                                               became dominant
 Mesozoic          240–65                      Origin of flowering plants and mammals
                                               Dinosaurs, insects, fishes became dominant
 Palaeozoic        570–240                     Origin of reptiles, early fishes, insects and
                                               spore bearing plants which became dominant
                                               Origin of simple marine invertebrates and
                                               animals with hard parts
 Cryptozoic        4 600–570                   Origin of protists (unicellular organisms)
                   (Pre-Cambrian)              Origin of photosynthetic bacteria

           3.5.1        According to the results in the table above, will the learners accept
                        or reject their hypothesis?                                                 (1)

           3.5.2        Explain your answer to QUESTION 3.5.1.                                      (2)

           3.5.3        Explain the implications to the evolution theory if fossils of
                        dinosaurs from the early Pre-Cambrian period were found.                    (2)

           3.5.4        Explain why the invertebrates might have appeared earlier than our
                        fossil record currently shows.                                              (2)
                                                                                                    (7)
                                                                                                    [30]

                                                                       TOTAL SECTION B:             60

Copyright reserved                                                               Please turn over

### Page 14

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)          14                            DBE/Feb.–Mar. 2012
                                                 NSC

SECTION C
QUESTION 4

4.1        The table below shows the percentage distribution of blood groups in a
           province in South Africa.

                                            BLOOD GROUPS
                      A                    B           AB                  O
                      35                   15          10                  40

           4.1.1        How many genes control the blood groups shown above?                          (1)

           4.1.2        Explain how it is genetically possible to have four blood groups in a
                        population.                                                                   (2)

           4.1.3        Draw a pie chart using the information in the table above. Show
                        ALL calculations.                                                             (8)
                                                                                                      (11)

4.2       Researchers observed that the height of a particular plant (Achillea
          millefolium) found at different altitudes varied.

          They carried out the following procedure:

          •   30 seeds of these plants were collected at each of four different altitudes.
          •   Each group of 30 seeds were then grown under the same environmental
              conditions in a greenhouse.
          •   The height of each plant was measured and the average for each group
              was calculated.
          •   The average height of each group was recorded next to the altitude at
              which the seeds were collected.
           The following results were obtained:

                        ALTITUDE                AVERAGE HEIGHT OF PLANTS
                           (m)                            (cm)
                          1 000                            75
                          1 500                            50
                          2 000                            35
                          2 500                            20

           4.2.1        State a conclusion from the above investigation.                              (3)

           4.2.2        Describe TWO things that the researchers did which ensured the
                        validity of the procedure.                                                    (2)

Copyright reserved                                                                 Please turn over

### Page 15

Downloaded from hlayiso.com
Life Sciences/P1 (Version 1) (Full-time)        15                            DBE/Feb.–Mar. 2012
                                               NSC

           4.2.3      In terms of natural selection, explain why the average height of the
                      plants at 2 500 m is different from the average height of the plants at
                      lower altitudes.                                                             (4)
                                                                                                   (9)

4.3        Describe how point mutations, frame-shift mutations and meiosis contribute to
           genetic variation.                                                                      (17)
                                                                            Synthesis:             (3)
                                                                                                   (20)

           NOTE:       NO marks will be awarded for answers in the form of flow
                       charts or diagrams.

                                                                       TOTAL SECTION C:            40
                                                                          GRAND TOTAL:             150

Copyright reserved

## Related documents

- [Life Sciences P2 Feb-March 2012 Afr Version 2](https://www.hlayiso.com/library/life-sciences-p2-feb-march-2012-afr-version-2/14d134e9-fba5-47bc-851d-966ce297c88b) — Life Sciences · QP · 2012 · Afr
- [Life Sciences P2 Feb-March 2012 Eng Version 1](https://www.hlayiso.com/library/life-sciences-p2-feb-march-2012-eng-version-1/ed007fd2-2cd3-4524-9232-4058398d68d5) — Life Sciences · QP · 2012 · Eng
- [Life Sciences P1 Nov 2012 Version 1 Eng](https://www.hlayiso.com/library/life-sciences-p1-nov-2012-version-1-eng/85605d81-57ce-4bb8-9be6-eaa17806c770) — Life Sciences · QP · 2012 · Eng
- [Life Sciences P2 Feb-March 2012 Memo Eng Version 2](https://www.hlayiso.com/library/life-sciences-p2-feb-march-2012-memo-eng-version-2/62f5811f-5098-444d-bb69-1c480216bf8f) — Life Sciences · Memo · 2012 · Eng
- [Life Sciences P1 Nov 2012 Version 1 Memo Afr](https://www.hlayiso.com/library/life-sciences-p1-nov-2012-version-1-memo-afr/bc664c37-1161-416b-9499-dd0861d22001) — Life Sciences · Memo · 2012 · Afr
- [Life Sciences P2 Feb-March 2013 Version 2 Eng](https://www.hlayiso.com/library/life-sciences-p2-feb-march-2013-version-2-eng/7d4fd245-1073-4172-8973-11c298679339) — Life Sciences · QP · 2013 · Eng

## More from Grade 12 Life Sciences

- [LEWENSWETENSKAPPE V1 MEMO GR12 SEPT 2025 watermark](https://www.hlayiso.com/library/lewenswetenskappe-v1-memo-gr12-sept-2025-watermark/ee8ac4d1-8b43-4b2a-87fc-d07277b88025) — Memo · 2025
- [LIFE SCIENCES P2 MEMO GR12 SEPT 2025 AFR watermark](https://www.hlayiso.com/library/life-sciences-p2-memo-gr12-sept-2025-afr-watermark/be114f07-9b13-48d1-9cae-e0ae8aec035b) — Memo · 2025 · Afr
- [Life Sciences Grade 12 NSC P1 MEMO September 2025 Free State](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-p1-memo-september-2025-free-state/ba194139-8ff7-481e-92f4-d961a5c8d23a) — Memo · 2025
- [Life Sciences Grade 12 NSC P2 MEMO September 2025 Free State](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-p2-memo-september-2025-free-state/470ae841-15a4-4ab3-a87b-abd2294edc20) — Memo · 2025
- [Life Sciences Grade 12 NSC P2 MEMO September 2025 Gauteng](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-p2-memo-september-2025-gauteng/bbdf9d27-c483-4cd4-af9f-287e699f482e) — Memo · 2025
- [Life Sciences Grade 12 NSC P2 MEMO September 2025 KZN](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-p2-memo-september-2025-kzn/f412416e-57d1-473d-886a-87c9fbb8823c) — Memo · 2025

## Collection

- [Grade 12 past papers](https://www.hlayiso.com/grade-12/past-papers)

---

Hlayiso: free CAPS and IEB past papers, memos, notes and study guides for South African learners. When citing, link the page URL above, not a PDF or /api/ URL.
