# Life Sciences Grade 12 P2 Eastern Cape June 2024 QP (Eng)

> Grade 12 Life Sciences Paper 2 question paper from the Eastern Cape June Exam 2024 (English), 17 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/life-sciences-p2-gr12-qp-june-2024-english/7d6b4dfa-8115-4412-9e83-62e6b39212e8
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Language: English
- Document type: Question paper
- Year: 2024
- Exam period: Eastern Cape June Exam
- Paper: 2
- Curriculum: CAPS
- Pages: 17

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## About this document

Life Sciences · Grade 12 · Eastern Cape June Exam · 2024 · English. Question paper, 17 pages. Read online or download the PDF.

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## Document text

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                           NATIONAL
                      SENIOR CERTIFICATE

                              GRADE 12

                             JUNE 2024

                         LIFE SCIENCES

MARKS:   150

TIME:    2½ hours

                    This question paper consists of 17 pages.

                        Hosted by www.ecexams.co.za

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2                                     LIFE SCIENCES                              (EC/JUNE 2024)

INSTRUCTIONS AND INFORMATION

Read the following instructions carefully before answering the questions.

1.     Answer ALL the questions.

2.     Write ALL the answers in the ANSWER BOOK.

3.     Start the answers to EACH question at the top of a NEW page.

4.     Number the answers correctly according to the numbering system used in this
       question paper.

5.     Present your answers according to the instructions of each question.

6.     ALL drawings MUST be done in pencil and labelled in blue or black ink.

7.     Draw diagrams, tables or flow charts ONLY when asked to do so.

8.     The diagrams in this question paper are NOT necessarily drawn to scale.

9.     Do NOT use graph paper.

10.    You must use a non-programmable calculator, protractor and a compass,
       where necessary.

11.    All calculations to be rounded off to TWO decimal spaces.

12.    Write neatly and legibly.

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(EC/JUNE 2024)                                LIFE SCIENCES                                       3

SECTION A

QUESTION 1

1.1 Various options are provided as possible answers to the following questions.
    Choose the correct answer and write only the letter (A–D) next to the question
    numbers (1.1.1 to 1.1.10) in the ANSWER BOOK, for example 1.1.11 D.

      1.1.1      Cells that can differentiate into any type of cells are called …

                 A    sex cells.
                 B    daughter cells.
                 C    stem cells.
                 D    haploid cells.

      1.1.2      Which ONE of the following processes is responsible for the production
                 of male gametes?

                 A    Spermatogenesis
                 B    Oogenesis
                 C    Ejaculation
                 D    Ovulation

      1.1.3      The diagram below shows a male and female fish during reproduction.
                 The female fish releases hundreds of ova into the water. The male fish
                 swims close by and releases his sperm over the eggs. The fertilised eggs
                 attach to water plants.

                                                                           sperm

                                                         ova

                                                      Eggs

                 The reproductive strategies represented above are …

                 A    external fertilisation and vivipary.
                 B    precocial development and ovovivipary.
                 C    internal fertilisation and ovipary.
                 D    external fertilisation and ovipary.

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4                                       LIFE SCIENCES                              (EC/JUNE 2024)

     1.1.4    The function of the chorion in the amniotic egg is to ...

              A      allow for gaseous exchange in the egg.
              B      control temperature in the egg.
              C      provide nutrients for the developing embryo.
              D      collect nitrogenous waste from for the developing embryo.

     1.1.5    The table below shows the anti-codons of tRNA that code for different
              amino acids found in human protein.

                           ANTI-CODONS OF tRNA           AMINO ACIDS
                                   CAA                      Valine
                                   CCC                      Glycine
                                   CGU                      Alanine
                                   AAA                   Phenylalanine
                                   UCG                    Asparagine
                                   UAC                    Methionine
                                   GGU                      Proline
                                   AGC                    Tryptophan
                                   UCA                      Serine

              What is the corresponding amino acid for the DNA base triplet TCG?

              A      Alanine
              B      Tryptophan
              C      Serine
              D      Asparagine

     1.1.6    The diagram below represents three phases of meiosis.

              The correct order of the phases is …

              A      1, 2 and 3.
              B      2, 3 and 1.
              C      1, 3 and 2.
              D      2, 1 and 3.

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(EC/JUNE 2024)                             LIFE SCIENCES                                    5

      1.1.7      The peripheral nervous system is made up of …

                 A    motor and sensory neurons.
                 B    sympathetic and parasympathetic nervous systems.
                 C    cranial and spinal nerves.
                 D    connector neurons.

      QUESTIONS 1.1.8 AND 1.1.9 REFER TO THE INFORMATION BELOW.

      In pea plants, yellow seed colour (Y) is dominant over green seed colour (y).
      Smooth seed texture (S) is dominant over wrinkled seed texture (s).
      A student crossed a plant which had yellow wrinkled seeds with a plant which
      had green smooth seeds.

      1.1.8      Which ONE of the following shows possible alleles present in a gamete
                 that is produced by the plant with yellow wrinkled seeds?

                 A    YYss
                 B    yySS
                 C    yS
                 D    Ys

      1.1.9      Which ONE of the following is a possible representation of the
                 genotypes of the P1 generation?

                 A    YYSS x yyss
                 B    Yyss x yySs
                 C    YYSS x yySs
                 D    Yyss x YySs

      1.1.10     Which ONE of the following monohybrid crosses will result in a
                 phenotypic ratio of 1 : 1?
                 A cross where …

                 A    both parents are heterozygous.
                 B    one parent is heterozygous and the other parent is homozygous
                      dominant.
                 C    one parent is heterozygous and the other parent is homozygous
                      recessive.
                 D    both parents are homozygous for the dominant characteristic.
                                                                             (10 x 2)    (20)

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6                                       LIFE SCIENCES                              (EC/JUNE 2024)

1.2     Give the correct biological term for EACH of the following descriptions. Write
        only the term next to the question numbers (1.2.1 to 1.2.10) in the ANSWER
        BOOK.

        1.2.1    A genetic disorder characterised by the absence of a blood-clotting
                 factor

        1.2.2    The phase of meiosis during which homologous chromosomes
                 separate and start moving towards opposite poles

        1.2.3    The defect in cell division that leads to Down syndrome

        1.2.4    The structure that is made up of chromatids joined by a centromere

        1.2.5    The structure in the cell responsible for producing spindle fibres during
                 meiosis

        1.2.6    A disease characterised by the breaking down of the myelin sheath

        1.2.7    An eye defect caused when the lens cannot flatten enough to focus the
                 light on the retina

        1.2.8    The structure that conducts the nerve impulse from the cochlea to the
                 cerebrum

        1.2.9    The hormone responsible for female secondary characteristics

        1.2.10 The fluid responsible for controlling the temperature of the developing
               human foetus
                                                                               (10 x 1)       (10)

1.3     Indicate whether each of the descriptions in COLUMN Ι, applies to A ONLY, B
        ONLY, BOTH A and B, or NONE of the items in COLUMN ΙΙ. Write A only, B
        only, both A and B, or none next to the question numbers (1.3.1 to 1.3.3) in
        the ANSWER BOOK.

                 COLUMN Ι                                  COLUMN ΙΙ
        1.3.1   Crossing over           A:     Genetic variation
                                        B:     Increase in number of chromatids
        1.3.2   Hypothalamus            A:     Controls breathing
                                        B:     Controls temperature
        1.3.3   Progesterone            A:     Formation of corpus luteum
                                        B:     Inhibits the secretion of LH
                                                                                   (3 x 2)     (6)

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(EC/JUNE 2024)                               LIFE SCIENCES                                      7

1.4 The diagram below represents a reflex arc.

      1.4.1      Give only the LETTER of the part that represents the:

                 (a)   Effector                                                                (1)

                 (b)   Interneuron/Connector neuron                                            (1)

                 (c)   Sensory neuron                                                          (1)

      1.4.2      Give the LETTER and NAME of the neuron in the diagram that is
                 probably damaged if a person is able to feel the heat of the candle’s
                 flame, but is not able to move their hand away.                               (2)

      1.4.3      State if the nerve impulse travels from D to E or from E to D.                (1)

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8                                        LIFE SCIENCES                          (EC/JUNE 2024)

1.5 The diagrams below represent the eye.

     1.5.1    Give the LETTER and NAME of the part that:

              (a)    Contracts to change the shape of the lens                            (2)

              (b)    Controls the amount of light that enters the eye                     (2)

              (c)    Is protected by the conjunctiva                                      (2)

     1.5.2    Study DIAGRAM 1 and DIAGRAM 2. What process is responsible for
              the change in the shape of part E?                                          (1)

     1.5.3    Which diagram (1 or 2) represents the state of the eye when a person is
              reading a book?                                                             (1)

                                                                  TOTAL SECTION A:         50

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(EC/JUNE 2024)                              LIFE SCIENCES                                      9

SECTION B

QUESTION 2

2.1 Below is a sketch of the structure of DNA done by Francis Crick.

      2.1.1      Give the name of the scientist that worked with Francis Crick to discover
                 the structure of DNA.                                                         (1)

      2.1.2      Describe the structure of DNA that is shown in the above sketch.              (1)

                 Samples from an ill person showed two different kinds of nucleic acids in
                 their cells – both their human DNA and the RNA of viral nucleic acids.
                 The results of the percentage of nitrogen bases for the nucleic acids in
                 the samples are shown in the table below.

                                               NITROGENOUS BASE
                  SAMPLE
                                  A            T            G          C            U
                      1           21           21           29         29
                      2           24           0            36         27           13

      2.1.3      Which sample (1 or 2) contains the human DNA?                                 (1)

      2.1.4      Explain ONE reason for your answer in QUESTION 2.1.3.                         (2)

      2.1.5      Draw a simple labelled diagram to show the components that make up
                 ONE nucleotide in DNA.                                                        (3)

      2.1.6      Tabulate ONE way in which an RNA nucleotide differs in structure from a
                 DNA nucleotide.                                                               (3)

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10                                                        LIFE SCIENCES                               (EC/JUNE 2024)

2.2 In the 1960s an insecticide, DDT, was widely used to control insect pest
    populations.
     The graph below shows the number of mosquitoes of 2 phenotypes:
     - Those resistant to DDT
     - Those non-resistant to DDT

                               100
                                                                               Non-resistant   Resistant
                               90

                               80

        Number of mosquitoes
                               70

                               60

                               50

                               40

                               30

                               20

                               10

                                0
                                        1965      1966      1967        1968         1969      1970

                                     Spraying starts               Spraying stopped
                                                         Year

     Scientists collected this data from 1965, when DDT was first used, through to 1970.
     Spraying with DDT was stopped in 1968. Scientists found that resistant mosquitoes
     have a single mutation in the gene named GSTe2. This mutation makes insects
     produce a protein that helps the breakdown of DDT so that it is no longer toxic. This
     means that the mosquito can survive by breaking down the poison into non-toxic
     substances.
     The normal DNA segment and the mutated DNA segment in the GSTe2 gene are
     shown below:

     2.2.1                       Write the sequence of the mRNA strand produced by the ‘Normal DNA’.              (2)
     2.2.2                       Describe the process during which the ‘Normal DNA’ strand is transcribed
                                 into mRNA.                                                                       (4)
     2.2.3                       Explain how this mutation resulted in the resistance to DDT in mosquitoes.       (4)

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(EC/JUNE 2024)                                LIFE SCIENCES                                     11

2.3 The diagram below shows some of the changes that take place during the
    menstrual cycle.

         Ovarian
          cycle

         Uterine
          cycle

                 Day    0                             14                            28

      2.3.1       The menstrual cycle is controlled by hormones. Name ONE hormone
                  which will increase in level between day 2 and day 10.                        (1)

      2.3.2       Give ONE observable reason for your answer to QUESTION 2.3.1.                 (1)

      2.3.3       Explain the evidence from the diagram which indicates that fertilisation
                  took place.                                                                   (3)

      2.3.4       Describe the developmental changes in the fertilised ovum until
                  implantation occurs in the uterus.                                            (6)

      2.3.5       Some females use an ovulation monitor so that they can be aware of the
                  days when they are fertile. These monitors measure the level of
                  hormones in the blood.

                  Explain which hormone is likely to be monitored by the ovulation monitor.     (3)

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12                                      LIFE SCIENCES                               (EC/JUNE 2024)

2.4 Read the information below.

     The American chestnut tree grows in the forests in America. Its nuts provide food
     for humans, habitat for wildlife, fruit for food for wildlife and are also a valuable
     source of timber. There used to be about 4 billion American chestnut trees but
     today only a few grow in the forests. The trees are under threat from a fungal
     disease called blight.

     Scientists have attempted to create blight-resistant chestnuts. They inserted a
     gene from wheat called O1 into the tree’s genome. The gene codes for the
     enzyme that protects the tree from blight.

     The diagram below shows the process used to create resistant chestnut trees.

     2.4.1    Name the technology used to produce the resistant American chestnut
              trees.                                                                           (1)

     2.4.2    Explain ONE way how the decrease in American chestnut trees will
              affect the biodiversity of the forest.                                           (2)

     2.4.3    Describe in your own words how the DNA of bacteria can be changed.               (5)

     2.4.4    Describe how the modified chestnut trees can have a negative effect on
              the environment.                                                                 (2)

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(EC/JUNE 2024)                             LIFE SCIENCES                                 13

2.5 The diagram below represents two phases of meiosis.

                       DIAGRAM A                            DIAGRAM B

      2.5.1      Identify the phase represented by DIAGRAM B.                            (1)

      2.5.2      Describe the events in the phase that follows DIAGRAM A.                (3)

      2.5.3      Name ONE place in the human female where meiosis takes place.          (1)
                                                                                       [50]

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14                                       LIFE SCIENCES                           (EC/JUNE 2024)

QUESTION 3
3.1 Menkes syndrome is caused by a sex-linked disease. It is caused by a mutation
    in the gene coding for a protein called ATP7A, which is responsible for
    transporting copper into cells. Symptoms include easily broken hair, a loss of
    early developmental skills, weak muscle tone, sagging facial features, seizures,
    and nervous system deterioration.

                                    1            2

             3                4     5            6         7              8

         9               10         11           12      13              14
                                                                     XRXR

                                                               Normal female
        15               16

                                                               Normal male

                                                               Male with Menkes
                                                               syndrome
                                                               sindroom

     3.1.1    Name the type of diagram shown above.                                       (1)

     3.1.2    Define a sex-linked disease.                                                (1)

     3.1.3    How many generations are shown in the diagram?                              (1)

     3.1.4    Is Menkes syndrome recessive or dominant?                                   (1)

     3.1.5    Give a reason for your answer in QUESTION 3.1.4.                            (3)

     3.1.6    Using symbols XR and Xr to provide the genotypes of the following
              individuals:

              (a)    Individual 2                                                         (1)

              (b)    Individual 5                                                         (1)

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(EC/JUNE 2024)                               LIFE SCIENCES                                      15

       3.1.7     Use a genetic cross to show the chances of the next child born from
                 individuals 13 and 14 (XRXR) will be born with Menkes syndrome.                (6)

       3.1.8     Explain why it is more common for boys to suffer from Menkes
                 syndrome than girls.                                                           (2)
 3.2 The diagram below represents a part of the human ear.

                                                      A

                                                                                   B

                                                                                   C

                                                                                   D

                                      G               F      E

       3.2.1     Provide labels for parts labelled:
                 (a)    D                                                                       (1)

                 (b)    E                                                                       (1)
       3.2.2     Give the LETTER and NAME of the part that:

                 (a)    Is responsible for directing sound waves to the middle ear              (2)

                 (b)    Contains receptor cells that detect change in direction of the
                                                                                                (2)
                        head
       3.2.3     Read the extract below.

                 Glue ear is a condition where fluid builds up inside your middle ear and
                 becomes thick and sticky. It is common in young children and often
                 occurs after a cold or an ear infection.

                 Glue ear can cause hearing loss.

                 The fluid may clear up by itself without treatment, but it can take up to
                 3 months. If the fluid doesn’t clear up, it can be treated with tiny tubes
                 called grommets that help the fluid drain.

                 (a)    Explain how glue ear leads to hearing loss.                             (4)

                 (b)    In which part of the ear is a grommet inserted?                         (1)

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16                                       LIFE SCIENCES                              (EC/JUNE 2024)

3.3 Refer to the diagram below.

     3.3.1      Give the names of parts labelled:

                (a)    C                                                                       (1)

                (b)    D                                                                       (1)

     3.3.2      Give the function of part B.                                                   (2)

     3.3.3      Give the LETTER and NAME of the part that would probably be
                damaged if a person suffered hearing loss after a car accident.                (2)

     3.3.4      A brain tumour is a mass or growth of cells in the brain which may affect
                the normal functioning of the brain.

                A young girl is taken to hospital as she is experiencing a loss of balance
                and fine motor skills. She is diagnosed with a brain tumour.

                Explain in which area of the brain the tumour is growing.                      (3)

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(EC/JUNE 2024)                                  LIFE SCIENCES                                 17

3.4 Anabolic android steroids (AAS) are widely used by athletes to gain muscle
    strength, shape, and performance. There is an increase in athletes using AAS
    and concern has been raised that AAS could affect male fertility.

      Scientists wanted to investigate the effect of AAS on male fertility.

      The study was conducted on 90 males who were divided into three groups:
      • 30 healthy male athletes who used AAS
      • 30 healthy male athletes that did not use AAS
      • 30 healthy males that did not participate in sport and did not use AAS

      Their sperm count per mℓ was measured to determine fertility.
      A high sperm count indicating a male is more fertile.

                                                  AVERAGE          TESTOSTERONE
       GROUP              TREATMENT             SPERM COUNT        CONCENTRATION
                                                (million per mℓ)       (ng/mℓ)
                       Athletes that took
            A                                        11,87                2,22
                       AAS
                       Athletes that did not
            B                                        47,46                5,55
                       take AAS
                       Non sport group who
            C                                         48,1                5,74
                       did not take AAS

      3.4.1      Why do athletes take AAS?                                                    (1)

      3.4.2      Give the:

                 (a)     Dependent variable                                                   (1)

                 (b)     Independent variable                                                 (1)

      3.4.3      Give TWO ways the scientists could have improved the validity of the
                 investigation.                                                               (2)

      3.4.4      Why was group B included in the investigation?                               (3)

      3.4.5      Explain the relationship between sperm count and testosterone levels.        (3)

      3.4.6      Explain ONE other factor that can reduce sperm production in men.           (2)
                                                                                            [50]

                                                                   TOTAL SECTION B:          100
                                                                      GRAND TOTAL:           150

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