# Life Sciences Grade 12 P2 NSC June 2018 Question Paper (Eng)

> Grade 12 Life Sciences Paper 2 question paper from the NSC June Exam 2018 (English), 16 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/life-sciences-p2-may-june-2018-eng/e78efdd0-ce65-49f0-bc16-1b123d2e07c4
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Question paper
- Year: 2018
- Exam period: NSC June Exam
- Paper: 2
- Curriculum: CAPS
- Pages: 16

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## About this document

Life Sciences · Grade 12 · NSC June Exam · 2018. Question paper, 16 pages. Read online or download the PDF.

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                     SENIOR CERTIFICATE EXAMINATIONS

                                  LIFE SCIENCES P2

                                          2018

                                                                      MARKS: 150

                                                                    TIME: 2½ hours

                        This question paper consists of 16 pages.

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Life Sciences/P2                             2                                    DBE/2018
                                            SCE

INSTRUCTIONS AND INFORMATION

Read the following instructions carefully before answering the questions.

1.        Answer ALL the questions.

2.        Write ALL the answers in the ANSWER BOOK.

3.        Start the answers to EACH question at the top of a NEW page.

4.        Number the answers correctly according to the numbering system used in this
          question paper.

5.        Present your answers according to the instructions of each question.

6.        Do ALL drawings in pencil and label them in blue or black ink.

7.        Draw diagrams, tables or flow charts only when asked to do so.

8.        The diagrams in this question paper are NOT necessarily drawn to scale.

9.        Do NOT use graph paper.

10.       You must use a non-programmable calculator, protractor and a compass,
          where necessary.

11.       Write neatly and legibly.

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Life Sciences/P2                               3                                    DBE/2018
                                              SCE

SECTION A

QUESTION 1

1.1       Various options are provided as possible answers to the following questions.
          Choose the answer and write only the letter (A to D) next to the question
          numbers (1.1.1 to 1.1.9) in the ANSWER BOOK, e.g. 1.1.10 D.

          1.1.1      Which ONE of the following is a mechanism of reproductive
                     isolation?

                     A    Extinction
                     B    Breeding at different times of the year
                     C    Mutation
                     D    Independent assortment

          1.1.2      Who formulated the law of use and disuse?

                     A    Lee Berger
                     B    Rosalind Franklin
                     C    Gregor Mendel
                     D    Jean Baptiste de Lamarck

          1.1.3      Which ONE of the following features is found in BOTH humans and
                     African apes?

                     A    Short upper arms
                     B    Claws instead of nails
                     C    Opposable thumbs
                     D    Small brain

          1.1.4      Scientists made an observation that some species of butterfly are
                     more numerous during wet summers than dry summers. In order to
                     investigate this, the next step would be to …

                     A    record the results.
                     B    state a hypothesis.
                     C    measure the results.
                     D    draw a conclusion.

          1.1.5      Which ONE of the following is the CORRECT definition of
                     a species? A group of …

                     A    similar organisms that live in the same habitat at the same time
                     B    similar organisms that have the same chromosome number
                     C    organisms that are similar in size, shape and colour
                     D    similar organisms that are able to interbreed to produce fertile
                          offspring

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Life Sciences/P2                                  4                                     DBE/2018
                                                 SCE

          QUESTIONS 1.1.6 AND 1.1.7 REFER TO THE DIAGRAM BELOW
          SHOWING THE INHERITANCE OF HAEMOPHILIA IN A FAMILY.

                                             1             2

                               3       4               5       6    7

                     KEY:
                            Female without                         Male without
                            haemophilia                            haemophilia

                            Female with haemophilia                Male with haemophilia

          1.1.6      Which ONE of the combinations in the table below is CORRECT for
                     BOTH individuals 1 and 5?

                                 PHENOTYPE OF                        GENOTYPE OF
                                   INDIVIDUAL 1                      INDIVIDUAL 5
                     A      Female without haemophilia                   XhXh
                     B      Female without haemophilia                    XhY
                     C      Female with haemophilia                      XHXh
                     D      Female without haemophilia                    XHY

          1.1.7      What is the percentage chance that individuals 3 and 4 would have
                     a child with haemophilia?

                     A    100%
                     B    75%
                     C    25%
                     D    0%

          1.1.8      A dye stains a particular type of nucleic acid red. When this dye was
                     used to identify which organelles in a cell contain this nucleic acid,
                     only the nucleus and ribosomes stained red.

                     This result shows that the dye stains structures that contain …

                     A    DNA.
                     B    RNA.
                     C    DNA and protein.
                     D    both DNA and RNA.

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Life Sciences/P2                                5                                       DBE/2018
                                               SCE

          1.1.9      Study the diagram below.

            PRESENT Vegetarian Small tree Medium tree Large tree           Mangrove Woodpecker
              DAY   tree finch   finch       finch       finch               finch     finch

             ONE MILLION                            Common
             YEARS AGO                            ancestor finch

                     Which present-day finch is LEAST related to all the others?

                     A    Woodpecker finch
                     B    Large tree finch
                     C    Mangrove finch
                     D    Vegetarian tree finch                                        (9 x 2)       (18)

1.2       Give the correct biological term for each of the following descriptions.
          Write only the term next to the question numbers (1.2.1 to 1.2.8) in the
          ANSWER BOOK.

          1.2.1      A diagrammatic representation of possible evolutionary relationships
                     amongst species

          1.2.2      The splitting of the cytoplasm during cell division

          1.2.3      The process whereby DNA makes an exact copy of itself

          1.2.4      A type of variation where there is a range of phenotypes for the
                     same characteristic

          1.2.5      The present-day distribution of living organisms

          1.2.6      The failure of chromosome pairs to separate during meiosis

          1.2.7      Similar structures in different species that show modification by
                     descent

          1.2.8      An individual having two non-identical alleles for a characteristic
                                                                                     (8 x 1)         (8)

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                                                   SCE

1.3       Indicate whether each of the descriptions in COLUMN I apply to A ONLY,
          B ONLY, BOTH A AND B or NONE of the items in COLUMN II. Write A only,
          B only, both A and B or none next to the question numbers (1.3.1 to 1.3.3)
          in the ANSWER BOOK.

                            COLUMN I                                 COLUMN II
          1.3.1      Law of inheritance of acquired        A:   Darwinism
                     characteristics                       B:   Modification by descent
          1.3.2      Humans select the characteristics     A:   Artificial selection
                     when breeding organisms               B:   Natural selection
          1.3.3      A testable statement that may be      A:   Theory
                     accepted or rejected                  B:   Law
                                                                                     (3 x 2)       (6)

1.4       The diagram below represents the process of translation.

                                                                     W

                                    AUUGCAGGUUAC
                           V
                                                                     X

                                                                 Y

                                                         Z

          1.4.1      Name:

                     (a)       Organelle X                                                         (1)

                     (b)       Molecules W and Y                                                   (2)

                     (c)       The monomer of molecule W                                           (1)

          1.4.2      Where in the cell is:

                     (a)       Organelle X found                                                   (1)

                     (b)       Molecule W formed                                                   (1)
                                                                                                   (6)

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Life Sciences/P2                                                 7                                            DBE/2018
                                                                SCE

1.5       Study the graph below.

                                       The change in cranial capacity in a few species over time

                                      2000

                                      1800

                                      1600

             Cranial capacity (cm )
            3
                                                                                                   Homo sapiens
                                      1400

                                      1200

                                      1000                                                 Homo erectus

                                      800

                                      600                                  Homo habilis

                                      400                             Australopithecus africanus

                                             4,0      3,0         2,0           1,0           0,0
                                                              Millions of years ago

          1.5.1                         Name the family to which all these species belong.                                 (1)

          1.5.2                         What is the largest cranial capacity (in cm3) of Australopithecus
                                        africanus?                                                                         (1)

          1.5.3                         When did Homo habilis become extinct?                                              (1)

          1.5.4                         Name TWO Australopithecus fossils found in South Africa.                           (2)

          1.5.5                         Which of the organisms represented above has the greatest range in
                                        cranial capacity?                                                                  (1)
                                                                                                                           (6)

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                                             SCE

1.6       Diagrams 1 to 3 below represent some of the phases of meiosis shown in the
          correct order.

                                  A
                                                              C
                                    B

                                                                  D

                                                              E

                           1                    2                          3

          1.6.1      Identify the phase represented by diagram:

                     (a)   1                                                                      (1)

                     (b)   3                                                                      (1)

          1.6.2      Give the LETTER only of the part that:

                     (a)   Contains DNA                                                           (1)

                     (b)   Attaches to the centromeres of chromosomes                             (1)

                     (c)   Forms the spindle fibres                                               (1)

          1.6.3      Name the organ in a human male where meiosis occurs.                         (1)
                                                                                                  (6)

                                                                      TOTAL SECTION A:            50

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Life Sciences/P2                                  9                               DBE/2018
                                                 SCE

SECTION B

QUESTION 2

2.1       When a thief broke into a car he cut his arm on the broken glass. Scientists
          extracted DNA from the blood found on the broken glass. They analysed this
          DNA sample and compared it to the DNA from three suspects, P, Q and R.

          The table below shows the results of the analysis for the DNA from each
          source.

                       Blood from
                       broken glass          P           Q       R

          2.1.1      What do the diagrams above represent?                                     (1)

          2.1.2      Which suspect is most likely the thief?                                   (1)

          2.1.3      Give a reason for your answer to QUESTION 2.1.2.                          (1)

          2.1.4      State TWO possible disadvantages of using this evidence in a court
                     of law.                                                                   (2)
                                                                                               (5)

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Life Sciences/P2                                     10                                 DBE/2018
                                                    SCE

2.2       Insulin is one of the hormones responsible for the control of blood
          glucose levels in humans. It is made up of two long amino acid chains, A
          and B, which are joined. Chain A is made up of 21 amino acids and chain B
          of 30 amino acids.
          The diagram below represents the amino acids present in each chain.

                                                    X
           Ile     Val
                         Gln
                                                                                        Chain A
           Gly
                   Asn

            Val
                         Gln
                                                                                         Chain B
             Phe

          2.2.1          Name the process whereby insulin is produced in a normal human
                         cell.                                                                        (1)

          2.2.2          Identify bond X.                                                             (1)

          2.2.3          How many nitrogenous bases in a DNA molecule code for the amino
                         acids in chain A?                                                            (1)

          2.2.4          The table below shows the mRNA codons that code for some amino
                         acids.

                                mRNA CODON                           AMINO ACID
                                   UUC                            Phenylalanine (Phe)
                                   AUC                              Isoleucine (Ile)
                                   AAU                             Asparagine (Asn)
                                   GAA                            Glutamic acid (Glu)
                                   GUA                                Valine (Val)
                                   CAG                              Glutamine (Gln)
                                   CAU                               Histidine (His)
                                   GGA                               Glycine (Gly)

                         (a)   Name the nitrogenous base represented by G in the mRNA
                               codon CAG.                                                             (1)

                         (b)   Read the chains from left to right and give the:

                               (i)    Codon for the fourth amino acid in chain B                      (1)

                               (ii)   DNA base triplet that codes for the first amino acid in
                                      chain A                                                         (1)

                         (c)   Give the anticodon for valine.                                         (1)
                                                                                                      (7)
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Life Sciences/P2                                          11                                           DBE/2018
                                                         SCE

2.3       Describe the process of transcription.                                                                     (6)

2.4       The diagram below shows the karyotypes of two individuals.

                           INDIVIDUAL P                                    INDIVIDUAL Q

          1            2         3             4     5     1           2       3             4     5

          6        7         8       9    10   11   12         6   7       8        9   10   11   12
                                                           1
         13 14 15                          16 17 18        13 14 15                        16 17 18

          19 20                   21 22             23     19      20              21 22          23

          2.4.1             What term is given to the chromosomes numbered:

                            (a)      1 to 22                                                                         (1)

                            (b)      23                                                                              (1)

          2.4.2             State the gender of individual P.                                                        (1)

          2.4.3             Give ONE observable reason for your answer to QUESTION 2.4.2.                            (2)

          2.4.4             Each of the pairs shown is a homologous pair of chromosomes.

                            State the origin of each chromosome in a homologous pair of
                            chromosomes.                                                                             (2)
                                                                                                                     (7)

2.5       Lindiwe has two sons and she is now pregnant for the third time.

          Use a genetic cross to show the percentage chance that this child could be
          a boy.                                                                                                     (6)

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                                               SCE

2.6       In dogs, coat appearance is controlled by two genes; one for coat colour and
          one for coat pattern (presence or absence of white patches).

          The alleles for each characteristic are shown in the table below.

          CHARACTERISTIC                                  ALLELES
          Coat colour                         Black (B)                  Grey (b)
          Coat pattern                Without white patches (T)   With white patches (t)

          In a cross between two dogs, the four offspring, V, W, X and Y, had the
          phenotypes as shown in the diagram below.

                                 Phenotypes of the F1 generation

                     V                   W                  X                   Y

          2.6.1      What is the term given to a genetic cross involving two
                     characteristics?                                                             (1)

          2.6.2      Give the phenotype of:

                     (a)    The dominant coat colour                                              (1)

                     (b)    Dog V                                                                 (1)

                     (c)    A dog that is homozygous recessive for both characteristics           (1)

          2.6.3      Explain why all dogs with the phenotype of dog W may not have the
                     same genotype.                                                               (2)

          2.6.4      The two characteristics are inherited in accordance with Mendel's
                     principle of independent assortment.

                     State this principle.                                                        (3)
                                                                                                  (9)
                                                                                                  [40]

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Life Sciences/P2                               13                                  DBE/2018
                                              SCE

QUESTION 3

3.1       Read the extract below.

          Stem cell surgery has been performed for the first time in South Africa at a
          Cape Town hospital. A patient became paralysed in a diving accident. He had
          no movement or feeling in any of his limbs because his nerve cells were
          damaged. Embryonic stem cells were used in an attempt to correct a defect in
          the spinal cord of the patient. He has now developed partial sensation
          throughout the body.

          3.1.1      Explain why stem cells are suitable cells to use for the treatment of
                     this patient.                                                               (3)

          3.1.2      Explain why some people prefer the use of umbilical cords as a
                     source of stem cells rather than the use of human embryos.                  (2)
                                                                                                 (5)

3.2       A baby was kidnapped from a hospital immediately after she was born. Fifteen
          years later it was discovered that Mr and Mrs Thomas, who were raising her,
          were not her biological parents. Mr and Mrs George, whose baby was born
          around the same time, claimed that she was their child.

          The blood groups of both families are shown in the table below.

                             INDIVIDUAL             BLOOD GROUPS
                         Child                           O
                         Mr Thomas                       O
                         Mrs Thomas                      AB
                         Mr George                        B
                         Mrs George                       A

          3.2.1      How many genes control the inheritance of blood groups?                 (1)

          3.2.2      Name the individual whose blood group shows co-dominance.               (1)

          3.2.3      Explain why Mr and Mrs George could possibly be the parents of
                     this child.                                                             (3)
                                                                                             (5)

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Life Sciences/P2                              14                                  DBE/2018
                                             SCE

3.3       In a study to establish the mode of locomotion of some species, scientists
          compared the pelvic structure of their fossils. They established that two of
          these species had the ability to walk upright permanently. The diagrams (A, B
          and C) below show the pelvic structure of three species, drawn to scale.

                        A                          B                     C

          3.3.1      What term is used to describe organisms that are able to walk
                     upright permanently?                                                       (1)

          3.3.2      Which TWO diagrams above represent the pelvis of the organisms
                     in QUESTION 3.3.1?                                                         (2)

          3.3.3      Explain your answer to QUESTION 3.3.2.                                     (2)

          3.3.4      State ONE feature of the spine of the organism represented by C.           (1)
                                                                                                (6)

3.4       Tabulate THREE differences between the skulls of humans and African apes.             (7)

3.5       Read the extract below.

          Brine shrimp are small arthropods found in saltwater lakes. During favourable
          conditions female shrimps produce eggs that hatch into live young. However,
          when conditions are unfavourable, the shrimp produce cysts. Each cyst
          contains the embryo covered with a hard, protective covering. In this state the
          embryo stops growing and is said to be dormant. The embryo can remain in
          this dormant state for many years and the cyst will only hatch at the optimum
          salt concentration.

          Scientists wanted to investigate which salt concentration resulted in the
          highest percentage of hatched cysts.

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                                                SCE

          They did the following:

          •    Prepared salt solutions of different concentrations: 0%, 0,5%, 1%, 1,5%
               and 2%
          •    Placed 30 mℓ of each solution into one of five beakers
          •    Took samples of brine shrimp cysts using a dropper
          •    Counted the number of cysts in each sample
          •    Recorded this as the initial number of cysts
          •    Placed the samples into each of the five beakers
          •    Left the beakers at room temperature for 48 hours
          •    Recorded the number of cysts that hatched in each beaker
          •    Calculated the percentage of cysts that hatched

          The results are shown in the table below.

                  SALT             NUMBER OF          NUMBER OF         PERCENTAGE
              CONCENTRATION       CYSTS USED AT       CYSTS THAT       OF CYSTS THAT
                   (%)              THE START          HATCHED            HATCHED
                    0                   54                0                   0
                   0,5                  34                2                   6
                    1                   40                6                  15
                   1,5                  40                1                  2,5
                    2                   53                1                   X

          3.5.1      State TWO planning steps to consider before collecting the samples.           (2)

          3.5.2      State the:

                     (a)   Independent variable                                                    (1)

                     (b)   Dependent variable                                                      (1)

          3.5.3      Calculate the value of X in the table. Show ALL working.                      (3)

          3.5.4      State THREE factors that were kept constant in order to ensure the
                     validity of this investigation.                                               (3)

          3.5.5      Which salt concentration resulted in the highest percentage of
                     hatched cysts?                                                                (1)

          3.5.6      Use the theory of evolution through natural selection to explain how
                     the ability to produce cysts led to the survival of the brine shrimp.         (6)
                                                                                                   (17)
                                                                                                   [40]

                                                                    TOTAL SECTION B:               80

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Life Sciences/P2                            16                                  DBE/2018
                                           SCE

SECTION C

QUESTION 4

There was variation in neck length in a population of Galapagos tortoises. The original
population from the mainland was separated onto two islands with different
environmental conditions. Many years later it was established that speciation of the
tortoises had occurred.

Describe how mutations and meiosis lead to variation within a population and the role
of variation in the speciation of the tortoises.
                                                                           Content:        (17)
                                                                          Synthesis:       (3)

NOTE: NO marks will be awarded for answers in the form of a table, flow charts or
      diagrams.

                                                                 TOTAL SECTION C:          20
                                                                    GRAND TOTAL:           150

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