# Life Sciences Grade 12 P2 NSC June 2022 Question Paper (Eng)

> Grade 12 Life Sciences Paper 2 question paper from the NSC June Exam 2022 (English), 15 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/life-sciences-p2-may-june-2022-eng/3f5050fa-a36f-43eb-9457-8dee4d2ea79b
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Question paper
- Year: 2022
- Exam period: NSC June Exam
- Paper: 2
- Curriculum: CAPS
- Pages: 15

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Life Sciences · Grade 12 · NSC June Exam · 2022. Question paper, 15 pages. Read online or download the PDF.

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             SENIOR CERTIFICATE EXAMINATIONS/
         NATIONAL SENIOR CERTIFICATE EXAMINATIONS

                                LIFE SCIENCES P2

                                        2022

                                                                     MARKS: 150

                                                                   TIME: 2½ hours

                       This question paper consists of 15 pages.

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Life Sciences/P2                              2                                  DBE/2022
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INSTRUCTIONS AND INFORMATION

Read the following instructions carefully before answering the questions.

1.        Answer ALL the questions.

2.        Write ALL the answers in the ANSWER BOOK.

3.        Start the answers to EACH question at the top of a NEW page.

4.        Number the answers correctly according to the numbering system used in this
          question paper.

5.        Present your answers according to the instructions of each question.

6.        Do ALL drawings in pencil and label them in blue or black ink.

7.        Draw diagrams, tables or flow charts only when asked to do so.

8.        The diagrams in this question paper are NOT necessarily drawn to scale.

9.        Do NOT use graph paper.

10.       You must use a non-programmable calculator, protractor and a compass,
          where necessary.

11.       Write neatly and legibly.

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Life Sciences/P2                               3                                   DBE/2022
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SECTION A

QUESTION 1

1.1      Various options are provided as possible answers to the following questions.
         Choose the answer and write only the letter (A to D) next to the question
         number (1.1.1 to 1.1.10) in the ANSWER BOOK, e.g. 1.1.11 D.

          1.1.1       The components of a DNA molecule that provide the code for
                      protein synthesis are the …

                      A   sugars.
                      B   phosphates.
                      C   hydrogen bonds.
                      D   nitrogenous bases.

          1.1.2       During which stage of meiosis do spindle fibres begin to form?

                      A   Prophase
                      B   Metaphase
                      C   Anaphase
                      D   Telophase

          1.1.3       An individual has Down syndrome. In the karyotype there is an
                      abnormal number of chromosomes at chromosome pair …

                      A   13.
                      B   18.
                      C   21.
                      D   23.

          1.1.4       An individual that has received an identical allele from each parent
                      is described as being …

                      A   homologous.
                      B   dominant.
                      C   homozygous.
                      D   heterozygous.

          1.1.5       A plant species has a diploid chromosome number of 12.

                      Which ONE of the following is the haploid chromosome number for
                      this species?

                      A   24
                      B   12
                      C   6
                      D   36

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          1.1.6       Inheritance by multiple alleles in genetics refers to …

                      A    two alleles that influence two characteristics.
                      B    more than two alleles that influence one characteristic.
                      C    one allele that influences more than one characteristic.
                      D    more than two alleles that influence two characteristics.

          1.1.7       Which ONE of the following is a reproductive isolation mechanism?

                      A    Breeding at the same time of the year
                      B    Infertile offspring
                      C    Plant adaptation to the same pollinators
                      D    Improved fertilisation

          1.1.8       Normal human ova have …

                      A    22 autosomes and an X chromosome.
                      B    23 autosomes and an X chromosome.
                      C    22 autosomes and a Y chromosome.
                      D    23 autosomes and a Y chromosome.

          1.1.9       Which ONE of the following occurs in mitosis but NOT in meiosis?

                      A   Two cells are formed at the end of the division
                      B   Crossing over takes place
                      C   Homologous chromosomes arrange at the equator
                      D   Centrioles form at the poles of the cell

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          1.1.10      The graph below shows the percentage similarity between human
                      (Hu) DNA and the DNA of some species of African apes.

                                                    120

                         Percentage similarity to
                                                              98                96
                                                    100                                          94

                                                     80                                                    72

                                                     60

                              human DNA
                                                     40

                                                     20

                                                      0
                                                          Chimpanzee        Gibbon          Rhesus       Galago
                                                             (Ch)            (Gi)         monkey (Rm)     (Ga)
                                                                        Type of African ape

                      Which ONE of the following phylogenetic trees best represents the
                      information in the graph?
                     A                                                     B
                               Hu Ch Gi                            Ga                Hu Ga      Rm Gi     Ch

                                                            Rm

                                        Common ancestor

                                                                                               Common ancestor
                     C                                                      D
                                      Ga Rm Ch Hu Gi                                 Gi   Rm    Ch Hu

                                                                                           Ga

                                       Common ancestor                               Common ancestor

                                                                                                           (10 x 2)         (20)

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1.2       Give the correct biological term for each of the following descriptions.
          Write only the term next to the question numbers (1.2.1 to 1.2.10) in the
          ANSWER BOOK.

          1.2.1       Division of the cytoplasm of a cell during meiosis

          1.2.2       The sugar molecule present in a nucleotide of RNA

          1.2.3       The position of a gene on a chromosome

          1.2.4       The process during which a DNA molecule makes an exact copy of
                      itself

          1.2.5       Undifferentiated cells that may be stimulated to develop into any
                      type of body cell

          1.2.6       Mendel's principle which states that an organism possesses two
                      factors which separate so that each gamete contains only one of
                      these factors

          1.2.7       The evolutionary theory that proposes long periods where species
                      do not change, alternating with short periods where rapid changes
                      occur

          1.2.8       A tangled network of DNA and protein located within the nucleus

          1.2.9       The natural shape of the DNA molecule

          1.2.10      The phase in the cell cycle during which cell growth occurs
                                                                                    (10 x 1)      (10)

1.3       Indicate whether each of the statements in COLUMN I apply to A ONLY,
          B ONLY, BOTH A AND B or NONE of the items in COLUMN II. Write A only,
          B only, both A and B, or none next to the question numbers (1.3.1 to 1.3.3)
          in the ANSWER BOOK.

                         COLUMN I                             COLUMN II
          1.3.1 A group of similar organisms         A: Population
                that occurs in a particular place    B: Species
                at a particular time with the
                ability to interbreed
          1.3.2 The manipulation of biological       A: Biogeography
                processes to satisfy human           B: Biotechnology
                needs
          1.3.3 Discovered the structure of the      A: Francis Crick
                DNA molecule                         B: James Watson
                                                                                        (3 x 2) (6)

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1.4       In tomato plants, tall stems (T) are dominant over short stems (t) and red fruit
          (R) is dominant over yellow fruit (r).

          A farmer crosses a homozygous tall, yellow tomato plant with a plant that is
          heterozygous for both characteristics.

          1.4.1       Name this type of genetic cross.                                            (1)

          1.4.2       Give the genotype of a homozygous tall, yellow tomato plant.                (2)

          1.4.3       List the genotypes of ALL the possible gametes for a plant that is
                      heterozygous for both characteristics.                                      (4)
                                                                                                  (7)

1.5       Haemophilia is a sex-linked recessive trait (Xh). The pedigree diagram below
          shows the inheritance of haemophilia in a family.

                                             P        Q

                                         R                S       T

                                                                      U

          1.5.1       State what is represented by the squares on a pedigree diagram.             (1)

          1.5.2       State the number of:

                     (a) Generations represented in this pedigree diagram                         (1)

                     (b) Offspring of individuals P and Q                                         (1)

          1.5.3      Give the:

                     (a) LETTERS only, of females who have haemophilia                            (2)

                     (b) Genotype of individual R                                                 (2)
                                                                                                  (7)

                                                                      TOTAL SECTION A:            [50]

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SECTION B

QUESTION 2

2.1       The diagram below represents one cell in a phase of meiosis.

                                  C

                                                                    A

                                                                    B

          2.1.1       Identify the phase of meiosis shown.                                     (1)

          2.1.2       Give ONE observable reason for your answer to QUESTION 2.1.1.            (2)

          2.1.3      Identify structure:

                      (a)   A                                                                  (1)

                      (b)   B                                                                  (1)

          2.1.4       Describe the role of part B in the movement of chromosomes
                      during meiosis.                                                          (2)

          2.1.5       Draw a labelled diagram of structure C as it would appear in the
                      final phase of this meiotic division. Show the correct shading.          (4)
                                                                                               (11)

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2.2       The diagram below represents the process of protein synthesis in a cell.

                       W                                            X

                                                                              Y

                       Z     UACGUAAGCCCUGUCCUU

                                         ribosome

          2.2.1       Name the process which occurs at:

                      (a)   W                                                                     (1)

                      (b)   Y                                                                     (1)

          2.2.2       Identify:

                      (a)   Organelle X                                                           (1)

                      (b)   Molecule Z                                                            (1)

          2.2.3       State TWO locations of DNA in a cell, other than in the nucleus.            (2)

          2.2.4       Describe the process at W.                                                  (7)

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          The table below shows some tRNA anticodons with their corresponding
          amino acids.

                        tRNA ANTICODON                 AMINO ACID
                              CAG                         Valine
                              GAA                        Leucine
                              AUG                       Tyrosine
                              GGA                        Proline
                              UCG                         Serine
                              CAU                         Valine

          2.2.5       Name the:

                      (a)   DNA base triplet that codes for serine                                  (1)

                      (b)   First TWO amino acids coded for by molecule Z in the
                            diagram (the molecule is read from left to right)                       (2)

          2.2.6       What is the change in the sequence of nitrogenous bases in a DNA
                      molecule called?                                                              (1)

          2.2.7       The codon CUU (last codon) on molecule Z changed to CCU.

                      Explain the effect it would have on this particular protein molecule.         (3)
                                                                                                    (20)

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2.3       A family wanted to identify the biological father of a boy. The mother of the
          boy is known. Blood groups and DNA profiles of the mother, the boy and two
          males were used to determine paternity.

          The data below shows the results of the two procedures.

                                          BLOOD GROUPS

                         Mother          Boy         Male 1         Male 2
                            O             B           AB              B

                                           DNA PROFILES

                          Mother         Boy         Male 1      Male 2

          2.3.1       Explain why paternity of the boy could not be established using
                      blood groups only.                                                        (5)

          2.3.2       Who is the biological father of the boy according to the DNA
                      profiles?                                                                 (1)

          2.3.3       Explain your answer to QUESTION 2.3.2.                                    (3)

          2.3.4       State ONE other use of DNA profiling.                                     (1)
                                                                                                (10)

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2.4       The diagram below shows the inheritance of flower colour in snapdragon
          plants.

          The two alleles controlling flower colour are red (R) and white (W).

                                            crossed
                                              with

                                 Red                   White

                                             Pink

          2.4.1       State the type of dominance shown by the snapdragon plants.                   (1)

          2.4.2       Give a reason for your answer to QUESTION 2.4.1.                              (2)

          2.4.3       A gardener crossed two pink-flowered snapdragon plants.

                      Use a genetic cross to show the ratio of the expected phenotypes
                      in the offspring.                                                             (6)
                                                                                                    (9)
                                                                                                    [50]

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QUESTION 3

3.1      Diagrams A and B show the ventral (bottom) view of the skulls of two
         organisms. The diagrams are NOT drawn to scale.

                                  A                                 B
                                            foramen magnum

         3.1.1       Which diagram represents the skull of a bipedal organism?                      (1)

         3.1.2       Give ONE visible reason for your answer to QUESTION 3.1.1.                     (2)

         3.1.3       Tabulate TWO visible differences between the upper jaws in diagrams
                     A and B that represent trends in human evolution.                              (5)

         3.1.4       Explain the significance of the shape of the spine that is associated
                     with the skull in diagram B.                                                   (2)
                                                                                                    (10)

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3.2       The herbicide glyphosate is used to control weeds in maize fields.
          The herbicide kills the weeds, but it can also kill the maize plants. It has been
          found that some weeds developed resistance to glyphosate treatment.

          Scientists carried out an investigation to determine the development of
          glyphosate resistance in the weeds. The weeds were treated with the same
          concentration of glyphosate each year from 2009 to 2016 and the percentage
          of glyphosate resistant weeds in the field was recorded every year.

          The results are shown in the table below.

                                 YEAR           GLYPHOSATE RESISTANT
                                                     WEEDS (%)
                                 2009                   10
                                 2010                   20
                                 2011                   32
                                 2012                   42
                                 2013                   53
                                 2014                   58
                                 2015                   65
                                 2016                   65

          3.2.1      Describe the change in glyphosate resistance over the time of the
                     investigation.                                                                  (3)

          3.2.2      Calculate the percentage increase in glyphosate resistant weeds
                     from 2010 to 2015. Show ALL your working.                                       (3)

          3.2.3      Scientists isolated the gene for glyphosate resistance from the
                     weeds and used it to genetically modify the maize plants.

                     Explain the economic benefit of making the maize plants resistant
                     to glyphosate.                                                                  (3)

          3.2.4      Draw a bar graph to illustrate the results of the investigation in the
                     first four years.                                                               (6)
                                                                                                     (15)

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3.3      A population of lizards on an island, Island A, were well suited to feed mainly
         on insects. Scientists moved five adult pairs of this lizard species to a
         neighbouring island, Island B. Here they reproduced and a new population
         formed. Island B has a large supply of plants with tough fibrous leaves and
         fewer insects. Exposure to this new environment may have caused the lizards
         to undergo evolution.

         Thirty-six years later, scientists returned to Island B to conduct further
         investigations on the lizard population there. They observed that the jaw size
         of the lizards had increased. Scientists also analysed the stomach content of
         the lizards and found that it was mainly plant-based. They also confirmed that
         the two populations still belong to the same species.

          3.3.1      Describe how the scientists could confirm that there was a change
                     in jaw size between the lizards of Island A and the lizards of
                     Island B.                                                               (3)

          3.3.2      Explain how the larger jaws of the lizards on Island B would be
                     structurally suited to eat tough fibrous leaves.                        (3)

          3.3.3      How did the scientists determine that the two populations of lizards
                     on both islands still belong to the same species?                       (2)

          3.3.4      Explain the possible effect that the evolution of the lizards has on
                     biodiversity.                                                           (2)

          3.3.5      Use Darwin's theory of natural selection to explain the evolution of
                     lizards with larger jaws.                                               (7)
                                                                                             (17)

3.4      The 'Out of Africa' hypothesis is one explanation of the evolution of modern
         humans.

          3.4.1       State the 'Out of Africa' hypothesis.                                  (2)

          3.4.2       Name the family to which modern humans belong.                         (1)

          3.4.3       What genetic evidence is used to support the 'Out of Africa'
                      hypothesis?                                                            (1)

          3.4.4       Describe how fossil evidence is used to support the 'Out of Africa'
                      hypothesis.                                                            (4)
                                                                                             (8)
                                                                                             [50]

                                                                   TOTAL SECTION B:          100
                                                                      GRAND TOTAL:           150

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