# Life Sciences Grade 12 P2 NSC June 2023 Question Paper (Eng)

> Grade 12 Life Sciences Paper 2 question paper from the NSC June Exam 2023 (English), 14 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/life-sciences-p2-may-june-2023-eng/de026ce5-57ae-4f14-8b72-59bfae9b406d
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Question paper
- Year: 2023
- Exam period: NSC June Exam
- Paper: 2
- Curriculum: CAPS
- Pages: 14

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Life Sciences · Grade 12 · NSC June Exam · 2023. Question paper, 14 pages. Read online or download the PDF.

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                                  GRAAD 12

             SENIOR CERTIFICATE EXAMINATIONS/
         NATIONAL SENIOR CERTIFICATE EXAMINATIONS

                                 LIFE SCIENCES P2

                                         2023

                                                                     MARKS: 150

                                                                   TIME: 2½ hours

                       This question paper consists of 14 pages.

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Life Sciences/P2                              2                                  DBE/2023
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INSTRUCTIONS AND INFORMATION

Read the following instructions carefully before answering the questions.

1.        Answer ALL the questions.

2.        Write ALL the answers in the ANSWER BOOK.

3.        Start the answers to EACH question at the top of a NEW page.

4.        Number the answers correctly according to the numbering system used in this
          question paper.

5.        Present your answers according to the instructions of each question.

6.        Do ALL drawings in pencil and label them in blue or black ink.

7.        Draw diagrams, tables or flow charts only when asked to do so.

8.        The diagrams in this question paper are NOT necessarily drawn to scale.

9.        Do NOT use graph paper.

10.       You must use a non-programmable calculator, protractor and a compass,
          where necessary.

11.       Write neatly and legibly.

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Life Sciences/P2                                 3                                DBE/2023
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SECTION A

QUESTION 1

1.1      Various options are provided as possible answers to the following questions.
         Choose the answer and write only the letter (A–D) next to the question
         numbers (1.1.1 to 1.1.9) in the ANSWER BOOK, e.g. 1.1.10 D.

          1.1.1      According to Lamarck's theory for evolution, …

                     A     acquired characteristics are not inherited.
                     B     organisms evolve because they adapt to their environment.
                     C     there is variation amongst offspring.
                     D     environmental changes have no influence on species diversity.

          1.1.2      The genotype for a specific characteristic …

                     A     contains two chromosomes.
                     B     is the physical appearance of an individual.
                     C     is the composition of a gene pair.
                     D     is represented by one allele.

          1.1.3      After the discovery of a fossil, scientists classified it as an
                     African ape because it had a …

                     A     large cranium, a prognathous jaw and large canines.
                     B     small cranium, a non-prognathous jaw and large canines.
                     C     small cranium, a prognathous jaw and large canines.
                     D     large cranium, a prognathous jaw and small canines.

         1.1.4       The statements below describe the steps in the process of cloning
                     an animal.

                     (i)   The embryo is implanted into the uterus of an adult female for
                           development.
                     (ii) The nucleus from a somatic cell of the donor is extracted.
                     (iii) The nucleus from the somatic cell is inserted into the ovum.
                     (iv) The nucleus from the ovum of another individual is removed.
                     (v) The ovum with the new nucleus is given an electric shock to
                           stimulate cell division and the formation of the embryo.

                     Which combination shows the CORRECT order of the steps?

                     A     (ii) (iv) (iii) (v) (i)
                     B     (ii) (iii) (iv) (v) (i)
                     C     (i) (ii) (iii) (iv) (v)
                     D     (ii) (iv) (v) (iii) (i)

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          1.1.5      Shrubs of the family Proteaceae (e.g. Waratahs and proteas) can
                     be found in Australia, South America, Indo-China and parts of
                     Africa as shown on the map below.

                                   South
                                   America                Africa     Australia

                     It is hypothesised that all continents were once one large continent
                     called Pangaea and that they separated due to continental drift.

                     This is evidence that the family Proteaceae …

                     A   all belong to the same species.
                     B   are equally distributed on all continents.
                     C   became extinct when Pangaea separated.
                     D   arose from a common ancestor when Pangaea separated.

          1.1.6      The diagram below shows the DNA profiles of a girl, her mother
                     and four males.

                                                                   Males
                                Girl    Mother
                                                      1        2           3     4

                     Which male is the girl's biological father?

                     A   1
                     B   2
                     C   3
                     D   4
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          1.1.7      The following are characteristics of a group of animals:

                     (i)       Able to interbreed
                     (ii)      Occupy the same habitat
                     (iii)     Produce infertile offspring
                     (iv)      Belong to the same species

                     Which combination CORRECTLY represents a population?

                     A       (i), (ii), (iii) and (iv)
                     B       Only (i), (ii) and (iv)
                     C       Only (i), (ii) and (iii)
                     D       Only (i) and (iv)

          1.1.8      During Anaphase II of meiosis, the two chromatids of a
                     chromosome are pulled apart, each moving towards opposite poles
                     at a rate of 1 micrometre per second.

                     The distance, in micrometres, between the chromatids after
                     20 seconds is …

                     A       10.
                     B       20.
                     C       30.
                     D       40.

          1.1.9      Which ONE of the following indicates the type of variation for each
                     of the human characteristics given?

                                     Height                  Skin colour    Ear lobe types
                      A        discontinuous             continuous        discontinuous
                      B        continuous                continuous        discontinuous
                      C        discontinuous             discontinuous     continuous
                      D        discontinuous             continuous        continuous
                                                                                       (9 x 2)       (18)

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1.2       Give the correct biological term for each of the following descriptions.
          Write only the term next to the question numbers (1.2.1 to 1.2.7) in the
          ANSWER BOOK.

          1.2.1      The type of inheritance which produces an intermediate phenotype

          1.2.2      The point where adjacent chromatids overlap during crossing over

          1.2.3      The process whereby information is copied from DNA to RNA in the
                     nucleus of a cell

          1.2.4      The sugar found in a DNA molecule

          1.2.5      The bond that occurs between nitrogenous bases in a DNA
                     molecule

          1.2.6      The manipulation of an organism's genes to obtain a desired
                     characteristic

          1.2.7      The representation showing the arrangement of a diploid set of
                     chromosomes                                             (7 x 1)             (7)

1.3       Indicate whether each of the descriptions in COLUMN I apply to A ONLY,
          B ONLY, BOTH A AND B or NONE of the items in COLUMN II. Write A only,
          B only, both A and B or none next to the question numbers (1.3.1 to 1.3.3)
          in the ANSWER BOOK.

                          COLUMN I                                COLUMN II
          1.3.1      Source of variation in a       A:   random mating
                     species                        B:   random fertilisation
          1.3.2      An organism possesses two      A:   law of dominance
                     factors which separate so      B:   principle of independent
                     that each gamete contains           assortment
                     only one of these factors
          1.3.3      Reproductive isolating         A: breeding in the same season of
                     mechanism in species              the year
                                                    B: infertile offspring
                                                                                (3 x 2)          (6)

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1.4       The diagram below represents a cell in an early stage of meiosis.

                                                                      R
                                                                      S

                                                                      T

          1.4.1      Give the:

                     (a)   Phase of meiosis represented                                            (1)
                     (b)   Number of chromatids shown                                              (1)
                     (c)   Number of homologous chromosome pairs                                   (1)

          1.4.2      Identify structure:

                     (a)   R                                                                       (1)
                     (b)   S                                                                       (1)
                     (c)   T                                                                       (1)

          1.4.3      Name TWO organs in an animal where meiosis occurs.                            (2)
                                                                                                   (8)

1.5       The brinjal plant carries edible fruit. Scientists have been studying the
          inheritance of two genes, one for stem texture and the other for fruit shape.

          The stems can be smooth (N) or prickly (n), while the fruit shape can be
          round (R) or elongated (r).

          1.5.1      Name the type of cross that studies two characteristics.                      (1)

          1.5.2      State the:

                     (a)   Dominant characteristic for stem texture                                (1)
                     (b)   Recessive characteristic for fruit shape                                (1)

          1.5.3      Give the:

                     (a)   Genotype of a plant with a prickly stem and elongated fruit             (2)
                     (b)   Phenotype of a plant with the genotype NnRR                             (2)
                                                                                                   (7)
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1.6       The table below shows information on selected hominid fossils.

                                                                            Scientists
          Common name
                                   Species             Fossil site       responsible for
           of the fossil
                                                                            discovery
                                                     Malapa Cave
                                Australopithecus
                     P                              in the Cradle of           Q
                                     sediba
                                                      Humankind
                                                      Sterkfontein
            Taung Child                R                                       S
                                                         Caves

          1.6.1      Name fossil P.                                                              (1)

          1.6.2      Identify the species at R.                                                  (1)

          1.6.3      Give the name of the scientist at:

                     (a)    Q                                                                    (1)

                     (b)    S                                                                    (1)
                                                                                                 (4)

                                                                       TOTAL SECTION A:          50

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SECTION B

QUESTION 2

2.1       The diagram below represents a process that occurs during protein synthesis.

                                                              X

                                                               Y

                               Z      C   A U   A U     G     G A   C

          2.1.1      Identify molecule:
                     (a)   X                                                                  (1)

                     (b)   Z                                                                  (1)

          2.1.2      Give the nitrogenous base sequence of:

                     (a)   The DNA base triplet complementary to the middle codon on
                           molecule Z                                                         (2)

                     (b)   Y                                                                  (1)

          2.1.3      Name and describe the process shown in the diagram during the
                     formation of a protein.                                                  (7)
                                                                                              (12)

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2.2       The table below shows the codons that code for some amino acids.

                           mRNA codon                            Amino acid
                              AUG                                 methionine
                              CAU                                   histidine
                              CUA                                   leucine
                              GUA                                    valine
                              GAC                                aspartic acid
                              GAG                                glutamic acid
                              GAU                                aspartic acid

          A mutation caused a DNA base triplet to change from CTG to CTA.

          Describe the effect of this mutation on the protein formed.                                 (4)

2.3       Tabulate TWO differences between DNA and RNA nucleotides.                                   (5)

2.4       Down syndrome is the result of an individual having an extra copy of
          chromosome 21.

          Two genetic variations that can cause Down syndrome are:

              Trisomy 21
               All the somatic cells in an individual have three copies of chromosome 21
               due to an abnormal process that occurs during gamete production.

              Mosaic Down syndrome
               The individual has only some cells with an extra copy of chromosome 21
               which is caused by an abnormal process during cell division after
               fertilisation.

          2.4.1      Name the:
                     (a) Type of mutation that leads to Trisomy 21                                    (1)

                     (b) Abnormal process during gamete production that leads to three
                         copies of chromosome 21                                                      (1)

                     (c)   Type of cell division that occurs after fertilisation                      (1)

          2.4.2      Describe how the process in QUESTION 2.4.1(b) leads to
                     Trisomy 21.                                                                      (5)

          2.4.3      Describe TWO differences between Trisomy 21 and Mosaic Down
                     syndrome.                                                                        (4)
                                                                                                      (12)

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2.5       The diagram below shows the inheritance of Tay-Sachs, a rare disease which
          leads to the destruction of neurons. It is inherited as an autosomal disorder,
          controlled by two alleles, (T) and (t).

                                              1           2

                            3          4             5           6

                                 7
             Key:

                     Male without Tay-Sachs                   Male with Tay-Sachs

                     Female without Tay-Sachs                 Female with Tay-Sachs

          2.5.1       Describe what is meant by an autosomal disorder.                          (2)

          2.5.2       How many sons do individuals 1 and 2 have?                                (1)

          2.5.3       Using individuals 3, 4 and 7, explain why it can be concluded that
                      Tay-Sachs disease is controlled by a recessive allele.                    (5)

          2.5.4       Individuals 1 and 2 can produce children with three possible
                      genotypes.

                      List ALL the genotypes that have a 25% chance of being produced.          (2)
                                                                                                (10)

2.6       In humans, haemophilia is caused by a recessive allele on the
          X-chromosome (Xh).

          A woman, who is heterozygous for haemophilia, marries a man with
          haemophilia.

          Use a genetic cross to show the percentage chance of the couple having a
          daughter who is homozygous for normal blood clotting.                                 (7)
                                                                                                [50]

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Life Sciences/P2                                 12                                  DBE/2023
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QUESTION 3

3.1     Learners conducted an investigation to determine which blood group was the
        most common in their community.

        They collected information about the blood groups of 200 blood donors in each
        of the three blood donor clinics in their community. They did not include
        first-time donors in the investigation.

        The pie chart below shows the results of the investigation.

                             Percentage of each blood group in the sample

                                                                  Blood group A
                                                                      25%

              Blood group O
                   55%

                                                                        Blood group B
                                                                            15%

                                                             Blood group AB
                                                                    5%

        3.1.1        State the aim of the investigation.                                           (2)

        3.1.2        Answer the following questions:

                     (a)   State THREE planning steps to consider when conducting this
                           investigation.                                                          (3)

                     (b)   State ONE way in which the learners ensured the reliability of
                           the results.                                                            (1)

                     (c)   Give ONE reason why they did not include first-time donors.             (1)

        3.1.3        Calculate the number of participants that had blood group B. Show
                     ALL workings.                                                                 (3)

        3.1.4        Name the blood group which:

                     (a)   Has only recessive alleles in the genotype                              (1)

                     (b)   Is a result of co-dominance                                             (1)

        3.1.5        Give ALL the possible genotypes of the blood group represented by
                     25% of the donors.                                                            (2)
                                                                                                   (14)
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3.2       Dogs have been selected and bred over many years to produce
          approximately 340 different dog breeds. They have been bred for certain
          characteristics desirable to humans.

          An analysis of 736 base pairs of the cytochrome-b gene showed that grey
          wolves are the only direct ancestor to present-day dog breeds. All dog breeds
          belong to the species Canis familiaris.

          The table below shows some dog breeds and their desirable characteristics.

                   Grey wolf            Dog breeds               Characteristics

                                                                    Intelligent

                                          Poodle

                                                             Loving, affectionate and
                                                                      playful
                                            Pug

                                                            Outgoing and adventurous

                                      Saint Bernard

                                                             Strong, athletic and fast

                                  Rhodesian ridgeback

          3.2.1       Name the process whereby the different breeds of dogs were
                      produced.                                                                  (1)

          3.2.2       Describe how humans carried out the process named in
                      QUESTION 3.2.1.                                                            (3)

          3.2.3       Explain how it can be confirmed that all these dog breeds belong to
                      the same species.                                                          (2)

          3.2.4       Explain which of the dog breeds shown would best be used for
                      hunting.                                                                   (2)

          3.2.5       Explain how present-day dog breeds may be disadvantaged in
                      relation to their common ancestor.                                         (3)
                                                                                                 (11)

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3.3       Describe the process of speciation through geographic isolation.                      (7)

3.4       The diagram below represents the evolution of the family Hominidae.

                                                            Orang-utan

                            P                               Gorilla

                                 Q                          Bonobo

                                                 S

                                          R                 Chimpanzee

                                                            Human

          3.4.1      Name the type of diagram represented above.                                (1)

          3.4.2      Give the LETTER of the organism which:

                     (a)   Is the common ancestor of all hominids                               (1)

                     (b)   Shares the most recent common ancestor with the gorilla              (1)

          3.4.3      Name TWO organisms that:

                     (a)   Have S as a common ancestor                                          (2)

                     (b)   Are quadrupedal                                                      (2)

          3.4.4      Describe THREE anatomical features of the skeleton of a
                     quadrupedal hominid.                                                       (3)
                                                                                                (10)

3.5       Fossil evidence is used to support the 'Out-of-Africa' hypothesis.

          3.5.1 State the 'Out-of-Africa' hypothesis.                                           (2)

          3.5.2 Describe how fossil evidence is used to support the 'Out-of-Africa'
                hypothesis.                                                                     (6)
                                                                                                (8)
                                                                                                [50]

                                                                      TOTAL SECTION B:          100
                                                                         GRAND TOTAL:           150

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