# Life Sciences Grade 12 P2 NSC November 2016 QP (Eng)

> Grade 12 Life Sciences Paper 2 question paper from the NSC November Exam 2016 (English), 18 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/life-sciences-p2-nov-2016-eng/61b5aa98-c245-4f64-b3e2-feb02b04505d
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Question paper
- Year: 2016
- Exam period: NSC November Exam
- Paper: 2
- Curriculum: CAPS
- Pages: 18

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## About this document

Life Sciences · Grade 12 · NSC November Exam · 2016. Question paper, 18 pages. Read online or download the PDF.

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                                  GRAAD 12

                                  NATIONAL
                             SENIOR CERTIFICATE

                                    GRADE 12

                                LIFE SCIENCES P2

                                 NOVEMBER 2016

MARKS: 150

TIME: 2½ hours

                       This question paper consists of 18 pages.

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Life Sciences/P2                             2                          DBE/November 2016
                                            NSC

INSTRUCTIONS AND INFORMATION

Read the following instructions carefully before answering the questions.

1.        Answer ALL the questions.

2.        Write ALL the answers in the ANSWER BOOK.

3.        Start the answers to EACH question at the top of a NEW page.

4.        Number the answers correctly according to the numbering system used in this
          question paper.

5.        Present your answers according to the instructions of each question.

6.        Make ALL drawings in pencil and label them in blue or black ink.

7.        Draw diagrams, tables or flow charts only when asked to do so.

8.        The diagrams in this question paper are NOT necessarily drawn to scale.

9.        Do NOT use graph paper.

10.       You must use a non-programmable calculator, protractor and a compass,
          where necessary.

11.       Write neatly and legibly.

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Life Sciences/P2                                3                        DBE/November 2016
                                               NSC

SECTION A
QUESTION 1
1.1       Various options are provided as possible answers to the following questions.
          Write down the question number (1.1.1 to 1.1.9), choose the answer and
          make a cross (X) over the letter (A to D) of your choice in the ANSWER
          BOOK.
          EXAMPLE:

          1.1.10       A            B           C          D

          1.1.1       The theory of evolution by natural selection was first described
                      by …
                      A    Gregor Mendel.
                      B    Watson and Crick.
                      C    Jean Baptiste de Lamarck.
                      D    Charles Darwin.

          1.1.2       When an individual that is homozygous dominant for a particular
                      characteristic is crossed with an individual that is homozygous
                      recessive for the characteristic, all the offspring would be ...
                      A    homozygous dominant.
                      B    homozygous recessive.
                      C    heterozygous.
                      D    pure-bred.

          1.1.3       The absence of the protein melanin results in the disorder called …
                      A    haemophilia.
                      B    colour-blindness.
                      C    albinism.
                      D    Down syndrome.

         1.1.4        A hummingbird uses its long beak to feed on the nectar in flowers.
                      The reason that Lamarck would have provided for the long beak
                      of the hummingbird is that …

                      A    all hummingbirds have the same beak length.
                      B    there is natural variation in beak length and some birds are
                           therefore better suited to feed on nectar.
                      C    the more the hummingbird used its beak, the longer it grew.
                      D    hummingbirds with shorter beaks were more fit for survival.

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Life Sciences/P2                                           4                   DBE/November 2016
                                                          NSC

          QUESTIONS 1.1.5 TO 1.1.7 ARE BASED ON THE DIAGRAM BELOW,
          SHOWING THE RESULTS OF A PARTICULAR PROCEDURE.

                                  Crime scene             DNA from suspects
                                      DNA                 Mo    Joe    Tom

          1.1.5       The procedure shown above is called …

                      A       cloning.
                      B       DNA replication.
                      C       DNA profiling.
                      D       fingerprinting.

          1.1.6       The evidence in the diagram shows that …

                     A        only Tom was present at the scene of the crime.
                     B        Tom and Joe were present at the scene of the crime.
                     C        only Mo was present at the scene of the crime.
                     D        none of the three individuals were at the scene of the crime.

          1.1.7       Below is a list of possible uses of the procedure shown in the
                      diagram above:

                      (i)       Paternity testing
                      (ii)      Matching of tissues for organ transplants
                      (iii)     Identification from fingerprints
                      (iv)      Screening for genetic disorders

                      Which combination shows the CORRECT uses of the procedure?

                      A       (i), (ii), (iii) and (iv)
                      B       Only (i), (ii) and (iv)
                      C       Only (i), (ii) and (iii)
                      D       Only (i) and (iv)

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Life Sciences/P2                                           5                        DBE/November 2016
                                                          NSC

          QUESTIONS 1.1.8 AND 1.1.9 ARE BASED ON THE GRAPH BELOW,
          WHICH SHOWS THE COMPARISON OF DNA BETWEEN SPECIES A
          AND SPECIES B, C, D AND E.

                   Similar DNA

                   (percentage)

                                      A and B       A and C  A and D      A and E
                                                       Species

          1.1.8             Which statement is a valid conclusion that can be drawn from this
                            graph?

                            Species A is most closely related to …

                            A       species B.
                            B       species C.
                            C       species D.
                            D       species E.

          1.1.9             The percentage DNA similarities between species could be used
                            to show the following:

                            (i)       Similarities in protein synthesis
                            (ii)      Evidence for evolution
                            (iii)     Common ancestry

                            Which combination shows the CORRECT application of the use
                            of similarities in DNA between species?

                            A       (i), (ii) and (iii)
                            B       Only (i) and (ii)
                            C       Only (ii) and (iii)
                            D       Only (i) and (iii)                                      (9 x 2)       (18)

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Life Sciences/P2                                6                            DBE/November 2016
                                               NSC

1.2       Give the correct biological term for each of the following descriptions.
          Write only the term next to the question number (1.2.1 to 1.2.7) in the
          ANSWER BOOK.

          1.2.1       The organelle in the cytoplasm which is the site of protein synthesis

          1.2.2       The name of the bond that forms between amino acids in a protein
                      molecule

          1.2.3       The process by which a DNA molecule makes identical copies
                      of itself

          1.2.4       The name of the process when homologous chromosome pairs fail
                      to separate during meiosis

          1.2.5       The permanent disappearance of a species from earth

          1.2.6       A testable statement that may be accepted or rejected

          1.2.7       The type of nucleic acid that carries a specific amino acid         (7 x 1)      (7)

1.3       Indicate whether each of the descriptions in COLUMN I applies to A ONLY,
          B ONLY, BOTH A AND B or NONE of the items in COLUMN II. Write A only,
          B only, both A and B or none next to the question number (1.3.1 to 1.3.3)
          in the ANSWER BOOK.

                               COLUMN I                                 COLUMN II
          1.3.1      The selection and breeding of           A:    Natural selection
                     organisms with desirable                B:    Artificial selection
                     characteristics by humans
          1.3.2      An allele that is not shown/expressed   A:    Dominant
                     in the phenotype when found in the      B:    Recessive
                     heterozygous condition
          1.3.3      Pairing of nitrogenous bases            A:    DNA
                                                             B:    RNA
                                                                                          (3 x 2)      (6)

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Life Sciences/P2                                  7                         DBE/November 2016
                                                 NSC

1.4       The diagram below shows a part of a DNA molecule.

                                             1                              2

                                              G

                                             T

                                                       3

          1.4.1      Provide labels for:

                     (a)   1                                                                       (1)

                     (b)   2                                                                       (1)

                     (c)   3                                                                       (1)

          1.4.2      Give the number of nucleotides shown in the diagram.                          (1)

          1.4.3      Give ONE difference between the nitrogenous bases found in DNA
                     molecules and those found in RNA molecules.                                   (2)
                                                                                                   (6)

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Life Sciences/P2                                 8                       DBE/November 2016
                                                NSC

1.5       The diagram below represents a process that occurs during meiosis.

                                               A

                                                               B

                                                               C

                                  D

          1.5.1      Provide labels for:

                     (a)   A                                                                    (1)

                     (b)   B                                                                    (1)

                     (c)   D                                                                    (1)

          1.5.2      Give the function of the structure labelled B.                             (1)

          1.5.3      Name:

                     (a)   The process occurring at C                                           (1)

                     (b)   The phase in meiosis during which the process at C occurs            (1)

          1.5.4      State ONE reason why process C is significant.                             (1)
                                                                                                (7)

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Life Sciences/P2                                                           9                                DBE/November 2016
                                                                          NSC

1.6       The diagram below represents the possible evolution of the horse.

                                                                                      Equus equus (modern horse)
                                           0

                                           5
                                                                       Styohiparion
                                                                                                          Pliohippus
                                           10
                                                                       Megahippus

             Millions of years ago (mya)
                                                        Sinohippus
                                           15
                                                                                  Arcaeohippus

                                           20     Anchitherium                                           Merychippus

                                           25

                                           30

                                                                                                         Parahippus
                                           35
                                                                 Mesohippus

                                           40
                                                  Paleotherium
                                           45                                         Epihippus

                                           50

                                           55                          Hyracotherium

                                                                                      [Adapted from http://archaeologyinfo.com]

          1.6.1                                 Name the:

                                                (a) Common ancestor of all horses                                                   (1)

                                                (b) Genus most closely related to Megahippus                                        (1)

          1.6.2                                 When did Paleotherium become extinct?                                               (2)

          1.6.3                                 How long did it take for the modern horse to evolve from
                                                Hyracotherium?                                                                      (2)
                                                                                                                                    (6)

                                                                                                     TOTAL SECTION A:               50

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Life Sciences/P2                                 10                        DBE/November 2016
                                                NSC

SECTION B

QUESTION 2

2.1       The leaf colour in a plant is controlled by two alleles, green (G) and yellow (g).
          Thorns on plant stems are controlled by two alleles, presence of thorns (T)
          and no thorns (t).

          Two plants with the genotypes GGTT and ggtt were crossed. Their offspring
          were then left to pollinate each other.

          The table below shows the possible genotypes of the offspring of the second
          generation. Genotypes (i) and (ii) have been left out.

                   Gametes         GT            Gt        gT            gt
                     GT           GGTT          GGTt      GgTT         GgTt
                     Gt           GGTt          GGtt      (i)…          Ggtt
                     gT           GgTT          GgTt      ggTT         ggTt
                     gt           GgTt          Ggtt      ggTt         (ii)…

          2.1.1       Give the:

                      (a)   Genotype of (i)                                                        (1)

                      (b)   Phenotype of (ii)                                                      (2)

          2.1.2       List the FOUR genotypes of the offspring of the second generation
                      that would be phenotypically different from the original pair
                      of parents.                                                                  (4)
                                                                                                   (7)

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Life Sciences/P2                                  11                         DBE/November 2016
                                                 NSC

2.2       The diagram below represents a phase in meiosis.

          Cell 1 undergoes division to give rise to cells 2 and 3. Some alleles are
          indicated by letters.

                                                 Cell 1

                     Cell 2                                                 Cell 3
                                            R     RR      R

                                             T     T t      t

          2.2.1         Explain why cell 1 does NOT belong to a human.                              (2)

          2.2.2         How many chromosomes would be present in:

                        (a) Cell 2 at the end of telophase I                                        (1)

                        (b) The daughter cells produced by cell 3 after meiosis II                  (1)

          2.2.3         Draw a labelled diagram of a gamete that will result from cell 2.           (5)
                                                                                                    (9)

2.3       State Mendel's law of segregation.                                                        (3)

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Life Sciences/P2                                        12                        DBE/November 2016
                                                       NSC

2.4       Huntington's chorea is a disease caused by a gene mutation that results in
          the degeneration of brain tissue. It is caused by a dominant allele (H).

          The pedigree diagram below shows the inheritance of this disorder in a family.

                                        Karl           Sarah

                   Lisa          Liam           Kate           Susan   Sean

                          John          Alexa                Emma          Jo         Paul

                            KEY
                                    Woman with                         Man with
                                    Huntington's chorea                Huntington's
                                                                       chorea

                                    Woman without                      Man without
                                    Huntington's chorea                Huntington's
                                                                       chorea

          2.4.1       What is:

                      (a) Susan's phenotype                                                              (1)

                      (b) Sarah's genotype                                                               (1)

          2.4.2       Emma plans to have a baby. What must the father's genotype be
                      so that there is a 50% chance that their child will not have
                      Huntington's chorea?                                                               (1)

          2.4.3       Explain your answer to QUESTION 2.4.2.                                             (3)
                                                                                                         (6)

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Life Sciences/P2                                  13                          DBE/November 2016
                                                 NSC

2.5       The mutation that causes Huntington's chorea occurs when the CAG base
          triplet on the DNA molecule is repeated more than 35 times. This mutation
          results in the formation of a 'Huntington's protein', which causes the
          degeneration of neurons in the brain.

          The diagram below shows the process whereby an mRNA molecule is formed
          from the DNA molecule.

                                                                      strand 2

                                            X                          G
                                                                     CA
                                         AT
                   mRNA                         G C A G C AG C A G

                                                                     strand 1

                                                                [Adapted from www.shutterstock.com]

          2.5.1      Name the process represented in the diagram.                                     (1)

          2.5.2      Where in the cell does this process occur?                                       (1)

          2.5.3      Give the:

                     (a)   Complementary bases on DNA strand 2 for a CAG triplet                      (1)

                     (b)   Sequence of bases at X                                                     (1)

          The table below shows the amino acids coded for by mRNA codons.

                             mRNA CODON                 AMINO ACID
                                UAC                       Tyrosine
                                AUG                      Methionine
                                CAG                      Glutamine
                                GUC                        Valine

          2.5.4      Which amino acid will occur more than 35 times in a 'Huntington's
                     protein'?                                                                        (2)

          2.5.5      Explain how a mutation results in the formation of a different protein.          (3)
                                                                                                      (9)

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Life Sciences/P2                               14                           DBE/November 2016
                                              NSC

2.6       You have two rose plants, both with pink flowers. You cross them and find
          that, while most of the offspring are pink, some are red and some are white.

          Use a genetic cross to show how breeding two pink flowering plants can
          result in pink, red and white flowering plants.

          Use the letter R for the red allele and W for the white allele.                         (6)
                                                                                                  [40]

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Life Sciences/P2                              15                           DBE/November 2016
                                             NSC

QUESTION 3

3.1       Read the passage below.

                              GENETIC MODIFICATION OF CROPS

          Genetic modification (GM) of crops began with the discovery that the soil
          bacterium Agrobacterium could be used to transfer useful genes from
          unrelated species into plants.

          The gene called Bt, which produces a pesticide toxin that is harmless to
          humans, but is capable of killing insect pests, is one of the genes most
          commonly inserted into crop plants. Many new GM crops, such as maize,
          potatoes and tomatoes, are modified to be pest, disease or weed-killer
          resistant.

          GM foods could have unforeseen effects. Toxic proteins may be produced or
          antibiotic-resistance genes may be transferred to human gut bacteria.
          Modified crops could become weed-killer resistant 'super weeds'. Modified
          crops could also 'accidentally' breed with wild plants or other crops.

                                            [Adapted from GM Organisms www.newscientist.com]

          3.1.1       According to the passage, how did genetic modification of crops
                      begin?                                                                      (1)

          3.1.2       Explain why a plant, which is modified to be weed-killer resistant,
                      could be a problem for farmers.                                             (2)

          3.1.3       Give TWO examples in the passage of the use of GM crops that
                      may be a potential threat to human health.                                  (2)
                                                                                                  (5)

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Life Sciences/P2                                16                              DBE/November 2016
                                               NSC

3.2       Lizards of a certain species on an island are usually brown in colour.
          A mutation in one gene for body colour results in red or black lizards.
          Black lizards camouflage well against the dark rocks and warm up faster on
          cold days which will give them energy to avoid predators.

          Scientists investigated the relationship between the colour of lizards in
          a population and their survival rate on an island.

          They conducted the investigation as follows:

          •    They selected a group of lizards of a certain species in a habitat.
          •    They recorded the percentage of each colour (brown, red or black) in
               the selected group.
          •    They repeated the investigation over a period of 30 generations
               of offspring.

          The results of the investigation are shown in the table below.

              COLOUR OF                  PERCENTAGE (%) OF EACH COLOUR
               LIZARDS                         IN THE POPULATION
                                     Initial       10th       20th       30th
                                   population   generation generation generation
                   BROWN               80           80         70         40
                    RED                10           0          0          0
                   BLACK               10           20         30         60
                                                          [Adapted from http//.hhmi.org/biolactive]

          3.2.1       State the:

                      (a)   Independent variable                                                        (1)

                      (b)   Dependent variable                                                          (1)

          3.2.2       Explain the effect of the mutation on the survival of the red lizards.            (2)

          3.2.3       Explain why the scientists had to conduct this investigation over
                      30 generations.                                                                   (2)

          3.2.4       State TWO ways in which the scientists could have improved the
                      validity of the investigation.                                                    (2)

          3.2.5       Use the theory of natural selection to explain the higher percentage
                      of black lizards in the population of the 30th generation.                        (6)

          3.2.6       Draw a bar graph to compare the percentage of the brown and the
                      black lizards in the initial population and the 30th generation.                  (6)
                                                                                                        (20)

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Life Sciences/P2                               17                          DBE/November 2016
                                              NSC

3.3       The diagram below shows the distribution of members of the camel family on
          the different continents. The arrows indicate the current distribution of
          the animals.

                                                                 Llama
          Dromedary            Bactrian

                                                        [Adapted from http://www.ck12.org]

          Explain how speciation of camels may have occurred.                                      (6)

3.4       Human blood groups are controlled by multiple alleles.

          3.4.1      Name ALL the alleles that control human blood groups.                         (3)

          3.4.2      How many of the alleles named in QUESTION 3.4.1 can any
                     individual inherit?                                                           (1)

          3.4.3      Give a reason for your answer to QUESTION 3.4.2.                              (2)

          3.4.4      A man has blood group A and his wife has blood group B. Their first
                     child has blood group AB and the second child has blood group O.

                     What can one conclude about the blood groups of their future
                     children?                                                                     (3)
                                                                                                   (9)
                                                                                                   [40]

                                                                     TOTAL SECTION B:              80

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Life Sciences/P2                           18                        DBE/November 2016
                                          NSC

SECTION C

QUESTION 4

Fossils of the bipedal primates Ardipithecus, Australopithecus and early Homo species
are used to support the 'Out of Africa' hypothesis.

State the 'Out of Africa' hypothesis. Describe the evidence that supports the 'Out of
Africa' hypothesis and the evidence that shows that the three primate genera
mentioned above, were all bipedal.
                                                                            Content:     (17)
                                                                           Synthesis:    (3)
                                                                                         (20)

NOTE: NO marks will be awarded for answers in the form of tables, flow charts
      or diagrams.

                                                                TOTAL SECTION C:         20
                                                                   GRAND TOTAL:          150

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