# Life Sciences Grade 12 P2 NSC November 2021 Memo (English)

> Grade 12 Life Sciences Paper 2 memorandum from the NSC November Exam 2021 (English), 12 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/life-sciences-p2-nov-2021-mg-eng/6e8a4d11-dd73-4b98-8390-0bcfb821de66
- Updated: 2026-10-29
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Memorandum
- Year: 2021
- Exam period: NSC November Exam
- Paper: 2
- Curriculum: CAPS
- Pages: 12

Breadcrumbs: [Home](https://www.hlayiso.com/) › [Library](https://www.hlayiso.com/library) › [Grade 12](https://www.hlayiso.com/library/grade-12) › [Life Sciences](https://www.hlayiso.com/library/grade-12/life-sciences) › [Life Sciences Grade 12 P2 NSC November 2021 Memo (English)](https://www.hlayiso.com/library/life-sciences-p2-nov-2021-mg-eng/6e8a4d11-dd73-4b98-8390-0bcfb821de66)

## About this document

Life Sciences · Grade 12 · NSC November Exam · 2021. Memorandum. Read online or download the PDF.

Read it free online on the page above; download the PDF from there.

## Document text

Text extracted from the PDF. Layout, diagrams and tables may not survive extraction.

### Page 1

Downloaded from hlayiso.com

                                 NATIONAL SENIOR
                                   CERTIFICATE

                                     GRADE 12

                                  LIFE SCIENCES P2

                                   NOVEMBER 2021

                               MARKING GUIDELINES

MARKS: 150

                      These marking guidelines consist of 12 pages.

Copyright reserved                                                    Please turn over

### Page 2

Downloaded from hlayiso.com
Life Sciences/P2                               2                           DBE/November 2021
                                    NSC – Marking Guidelines

PRINCIPLES RELATED TO MARKING LIFE SCIENCES

1.    If more information than marks allocated is given
      Stop marking when maximum marks is reached and put a wavy line and 'max' in
      the right-hand margin.

2.    If, for example, three reasons are required and five are given
      Mark the first three irrespective of whether all or some are correct/incorrect.

3.    If whole process is given when only a part of it is required
      Read all and credit the relevant part.

4.    If comparisons are asked for, but descriptions are given
      Accept if the differences/similarities are clear.

5.    If tabulation is required, but paragraphs are given
      Candidates will lose marks for not tabulating.

6.    If diagrams are given with annotations when descriptions are required
      Candidates will lose marks.

7.    If flow charts are given instead of descriptions
      Candidates will lose marks.

8.    If sequence is muddled and links do not make sense
      Where sequence and links are correct, credit. Where sequence and links are
      incorrect, do not credit. If sequence and links become correct again, resume
      credit.

9.    Non-recognised abbreviations
      Accept if first defined in answer. If not defined, do not credit the unrecognised
      abbreviation, but credit the rest of the answer if correct.

10. Wrong numbering
    If answer fits into the correct sequence of questions, but the wrong number is
    given, it is acceptable.

11. If language used changes the intended meaning
    Do not accept.

12. Spelling errors
    If recognisable, accept the answer, provided it does not mean something else in
    Life Sciences or if it is out of context.

13. If common names are given in terminology
    Accept, provided it was accepted at the national memo discussion meeting.

14. If only the letter is asked for, but only the name is given (and vice versa)
    Do not credit.

Copyright reserved                                                               Please turn over

### Page 3

Downloaded from hlayiso.com
Life Sciences/P2                               3                           DBE/November 2021
                                    NSC – Marking Guidelines

15. If units are not given in measurements
    Candidates will lose marks. Memorandum will allocate marks for units separately.

16. Be sensitive to the sense of an answer, which may be stated in a different
    way.

17. Caption
    All illustrations (diagrams, graphs, tables, etc.) must have a caption.

18. Code-switching of official languages (terms and concepts)
    A single word or two that appear(s) in any official language other than the learner's
    assessment language used to the greatest extent in his/her answers should be
    credited, if it is correct. A marker that is proficient in the relevant official language
    should be consulted. This is applicable to all official languages.
19. Changes to the memorandum
    No changes must be made to the memoranda. The provincial internal moderator
    must be consulted, who in turn will consult with the national internal moderator
    (and the Umalusi moderators where necessary).

20. Official memoranda
    Only memoranda bearing the signatures of the national internal moderator and the
    Umalusi moderators and distributed by the National Department of Basic
    Education via the provinces must be used.

Copyright reserved                                                              Please turn over

### Page 4

Downloaded from hlayiso.com
Life Sciences/P2                                4                DBE/November 2021
                                     NSC – Marking Guidelines

SECTION A

QUESTION 1

1.1       1.1.1       C
          1.1.2       D
          1.1.3       C
          1.1.4       A
          1.1.5       B
          1.1.6       D
          1.1.7       C
          1.1.8       C
          1.1.9       D                                                (9 x 2)        (18)

1.2       1.2.1       Phylogenetic tree/cladogram
          1.2.2       Peptidebond
          1.2.3       Punctuated equilibrium
          1.2.4       Homologous structures
          1.2.5       Artificial selection/selective breeding
          1.2.6       Co-dominance                                     (6 x 1)         (6)

1.3       1.3.1       Both A and B
          1.3.2       Both A and B
          1.3.3       None                                             (3 x 2)        (6)

1.4       1.4.1      (a) Nitrogenous base/Guanine/Cytosine                             (1)
                     (b) Deoxyribosesugar                                              (1)
                     (c) Hydrogen bond                                                 (1)

          1.4.2      Nucleotide                                                        (1)

          1.4.3      Double helix                                                      (1)

          1.4.4      (DNA) Replication                                                 (1)

          1.4.5      - Nucleus /Chromosome/Chromatid/ Chromatin/ Nucleoplasm
                     - Mitochondria                                                    (2)
                     (Mark first TWO only)                                              (8)

Copyright reserved                                                   Please turn over

### Page 5

Downloaded from hlayiso.com
Life Sciences/P2                               5                      DBE/November 2021
                                    NSC – Marking Guidelines

1.5       1.5.1      (a) Testis                                                             (1)
                     (b) Crossing over                                                      (1)

          1.5.2      (a) Chiasma                                                            (1)
                     (b) Centromere                                                         (1)
                     (c) Chromatid                                                          (1)
                                                                                             (5)

1.6       1.6.1      ffHh                                                                   (1)

          1.6.2      (a)   FfHh                                                            (2)
                     (b)   3                                                                (1)
                     (c)   h                                                                (1)
                     (d)   Long fingers and continuous hairline                            (2)
                                                                                             (7)

                                                                    TOTAL SECTION A: 50

Copyright reserved                                                        Please turn over

### Page 6

Downloaded from hlayiso.com
Life Sciences/P2                                 6                         DBE/November 2021
                                      NSC – Marking Guidelines

SECTION B

QUESTION 2

2.1       2.1.1      (a) Nucleus/nucleoplasm                                                     (1)
                     (b) Ribosome/cytoplasm                                                      (1)

          2.1.2       DNA contains thymine/T whereas RNA contains uracil/U                      (2)
                      (Mark first ONE only)

          2.1.3       Transcription*
                      - The double helix (DNA) molecule unwinds
                      - The double-stranded DNA unzips/weak hydrogen bonds
                         break
                      - to form two separate strands
                      - One strand is used as a template
                      - to form mRNA
                      - using free RNA nucleotides from the nucleoplasm
                      - The mRNA is complementary to the DNA/ A-U, G-C
                      - mRNA now has the coded message for protein synthesis
                                                        *1 compulsory mark + Any 5                (6)
                                                                                                  (10)

2.2       -   When chromosome pair 21/chromosome 21 fails to separate
          -   during Anaphase
          -   the daughter cells (gametes) will have 24 chromosomes/ an extra
              chromosome
          -   When this gamete is fertilised by a normal gamete with 23 chromosomes
          -   the zygote will have 47 chromosomes/3 chromosomes at position 21/
              Trisomy 21                                                                          (5)

2.3       2.3.1       Body cells/cells in the body except the sex cells                          (1)
          2.3.2       Autosomes                                                                  (1)

          2.3.3       (a)    -   One chromosome comes from the sperm/father
                             -   and the other comes from the ovum/mother                        (2)
                      (b)    - Shape
                             - Size/length
                             - Position of genes/alleles
                             - Genes coding for same characteristic
                             - Location of centromere                               Any          (3)
                             (Mark first THREE only)

          2.3.4       -     Gonosomes are not identical/chromosomes at position 23 are
                            not identical
                      -     Individual 1 has XY gonosomes/is a male
                      -     Individual 2 has XX gonosomes/is a female                            (3)
                                                                                                  (10)

Copyright reserved                                                             Please turn over

### Page 7

Downloaded from hlayiso.com
Life Sciences/P2                                 7                              DBE/November 2021
                                      NSC – Marking Guidelines

2.4       2.4.1      (a)    3/Three                                                                   (1)
                     (b)    2/Two                                                                     (1)

          2.4.2       Hearing                                                                         (1)

          2.4.3       -    Bob and Ann can both hear
                      -    They have a child who is deaf/who has the genotype aa
                      -    This means that each parent carries an allele for deafness/are
                           heterozygous/Aa
                      -    but it is maskedby the dominant allele/which is for hearing                (4)

          2.4.4       AA and Aa                                                                      (2)
                                                                                                       (9)

2.5        P1              Phenotype              Male           x     Female
                           Genotype                XY            x      XX
           Meiosis
                           G/gametes              X, Y           x     X, X
           Fertilisation
           F1              Genotype              XX;       XX;        XY; XY
                           Phenotype               female        :    male
           P1 and F1
           Meiosis and fertilisation
                                                   OR
           P1              Phenotype                Male         x     Female
                           Genotype                  XY          x     XX
           Meiosis
                                           Gametes               X              Y
           Fertilisation                      X                  XX            XY
                                              X                  XX            XY
                                            1 mark for correct gametes
                                            1 mark for correct genotypes

           F1           Phenotype                          female: male
           P1 and F1
           Meiosis and fertilisation                                                       Any        (6)

Copyright reserved                                                                  Please turn over

### Page 8

Downloaded from hlayiso.com
Life Sciences/P2                                8                           DBE/November 2021
                                     NSC – Marking Guidelines

2.6       2.6.1       - Spine
                      - Hips                                                                        (2)
                      (Mark first TWO only)

          2.6.2       -   A change in the sequence
                      -   of nitrogenous bases/nucleotides in DNA                                   (2)

          2.6.3       -   To check for the gene mutation
                      -   and if it results in the high bone density                                (2)

          2.6.4       Produces high bone density/reduces the risk of bone fractures                 (1)

          2.6.5
                           x 100 = 65%          OR              x 100 = 35%
                                                                (100 – 35) = 65%                   (3)
                                                                                                     (10)
                                                                                                     [50]

Copyright reserved                                                                Please turn over

### Page 9

Downloaded from hlayiso.com
Life Sciences/P2                                9                         DBE/November 2021
                                     NSC – Marking Guidelines

QUESTION 3

3.1        3.1.1      - The nucleus of the somatic cell is diploid/ has a full set of
                        chromosomes/has all the genetic material whereas
                      - the nucleus of the sperm cell is haploid/contains half the set of
                        chromosomes/ has half the genetic material
                      - The somatic cell carries the desired characteristic/straight hair        (3)

           3.1.2     To ensure that:
                     - The DNA (of the ovum)/characteristic of curly hair is removed
                     - Only the desired DNA is present in the clone
                     - Correct number of chromosomes is present in the clone Any                 (2)

           3.1.3     (Horse) S                                                                   (1)

           3.1.4     -  To produce organisms with desired traits e.g. health,
                        appearance, nutritious, yield, shelf life etc.
                     - Conservation of threatened species
                     - To create tissue/organs for transplant                         Any        (2)
                     (Mark first TWO only)                                                        (8)

3.2       3.2.1       -   Biogeography                                                           (1)
          3.2.2       -   Similar organisms
                      -   that can interbreed
                      -   to produce fertile offspring                                           (3)

          3.2.3       -   The original population /common ancestor once lived on a large
                          continent
                      -   and became separated by continental drift/oceans
                      -   There was no gene flow amongst the three populations*
                      -   Each population experienced different environmental
                          conditions
                      -   and underwent natural selection independently
                      -   The individuals in each population became different
                      -   genotypically and phenotypically
                      -   Even if the (three) populations are mixed again
                      -   they would not be able to interbreed/produce fertile offspring
                      -   forming the different species, the coyote, jackal and dingo *
                                                                     2 compulsory* + any 5        (7)
                                                                                                  (11)

Copyright reserved                                                             Please turn over

### Page 10

Downloaded from hlayiso.com
Life Sciences/P2                              10                          DBE/November 2021
                                    NSC – Marking Guidelines

3.3.1     -   It decreases the number of harmful bacteria the most
          -   thereby preventing disease in cattle/resulting in less medical expenses
          -   Decreasing mortality/maintaining the number of cattle
          -   to sell/breed /increase profit                                                        (4)

3.3.2     -   Natural selection occurs
          -   There is variation/mutation in the population of bacteria
          -   Some are resistant to antibiotics, some are non-resistant
          -   When antibiotic is added to the animal feed
          -   The bacteria that are non-resistant are killed by the antibiotic
          -   Those that are resistant survive and reproduce
          -   The characteristic for resistance to antibiotics is passed on to the
              offspring
          -   The next generation will have a higher proportion of antibiotic resistant              (6)
              bacteria                                                           Any                (10)

3.4       3.4.1      (a) Gall size                                                                  (1)

                     (b) Percentage of gallfly larvae killed                                        (1)

          3.4.2      - Nutrition/food
                     - Protection
                     - Space                                                            Any         (1)
                     (Mark first ONE only)

          3.4.3      -   There is a range of (intermediate) valuesin gall size                      (1)

          3.4.4      -   Larvae in 30mm galls are eaten more
                     -   since they are more visible to birds and
                     -   contain more/larger larvae
                                                         OR
                     -   Larvae in galls that are 25mm and smaller are eaten less
                     -   since they are less visible to birds and
                     -   contain fewer/smaller larvae                                               (3)

Copyright reserved                                                                Please turn over

### Page 11

Downloaded from hlayiso.com
Life Sciences/P2                                                  11                             DBE/November 2021
                                                        NSC – Marking Guidelines

          3.4.5

                                           Percentage of gallfly larvae killed by predatory
                                                  birds due to different gall sizes

          Gallfly larvae killed by
                                     12
                                                                                                        10
                                     10
                                     8
                                     6

           predatory birds (%)
                                     4
                                                                                        2
                                     2 1                               1
                                                        0
                                     0
                                          10           15             20               25               30
                                                                Gall size (mm)

       Guideline for the assessing of the graph
                                           CRITERIA                   ELABORATION                 MARK

               Correct type of graph (T)                       Line graph drawn                     1
               Caption of graph (C)                            Both variables included              1
               Axes labels (L)                                 Correct labels and units on
                                                               X- and Y-axes                        1

               Scale for X- and Y-axes (S)                     Equal spacing between
                                                                                                    1
                                                               intervals for each axis
               Plotting of points (P)                          1 to 4 points plotted correctly      1
                                                               All 5 points plotted correctly       2

                                                                                                                        (6)
                                                                                                                        (13)

Copyright reserved                                                                                   Please turn over

### Page 12

Downloaded from hlayiso.com
Life Sciences/P2                              12                     DBE/November 2021
                                    NSC – Marking Guidelines

3.5       3.5.1 (a)   X, Z (in any order)                                              (2)
                      (Mark first TWO only)

          3.5.1 (b)   C                                                                 (1)

          3.5.2       -    The pelvis is long
                      -    and narrow                                                   (2)

          3.5.3       - The spine
                      - is S-shaped for the bipedal organism
                      - and C-shaped for the quadrupedal organism
                                              OR
                      - The foramen magnum
                      - is in a more forward position in bipedal organisms
                      - and in a backward position in quadrupedal organisms             (3)
                      (Mark first ONE only)                                              (8)
                                                                                         (50)

                                                               TOTAL SECTION B:          100
                                                                  GRAND TOTAL:           150

Copyright reserved

## Related documents

- [Life Sciences P2 Nov 2021 Afr](https://www.hlayiso.com/library/life-sciences-p2-nov-2021-afr/6a0be2cc-cabc-40b2-a5fc-4dcf29d7b1b8) — Life Sciences · QP · 2021 · Afr
- [Life Sciences P1 Nov 2021 MG Afr](https://www.hlayiso.com/library/life-sciences-p1-nov-2021-mg-afr/49c0ade5-a6de-497f-beba-2a2361658df7) — Life Sciences · Memo · 2021 · Afr
- [LIFE SCIENCES P2 MEMO SEPT2021 Sesotho](https://www.hlayiso.com/library/life-sciences-p2-memo-sept2021-sesotho/83f68bb0-0ec1-4a72-a70a-994a6f9af99e) — Life Sciences · Memo · 2021 · Sesotho
- [Gr12 Life Sciences P2 (Afrikaans) 2021 Preparatory Possible Answers](https://www.hlayiso.com/library/gr12-life-sciences-p2-afrikaans-2021-preparatory-possible-answers/07d532e0-9e14-43cd-8b65-eafbe304db10) — Life Sciences · Memo · 2021 · Afr
- [Life Sciences P2 Nov 2019 Memo Eng](https://www.hlayiso.com/library/life-sciences-p2-nov-2019-memo-eng/d4ac5eda-a68e-4263-80fa-fa1e8d3b4cef) — Life Sciences · Memo · 2019 · Eng
- [Life Sciences P2 Nov 2019 Memo Afr](https://www.hlayiso.com/library/life-sciences-p2-nov-2019-memo-afr/be980b5b-1ccf-4b05-8f44-e4dee2a17852) — Life Sciences · Memo · 2019 · Afr

## More from Grade 12 Life Sciences

- [LIFE SCIENCES QP GR12 JUNE 2025 ENG D watermark](https://www.hlayiso.com/library/life-sciences-qp-gr12-june-2025-eng-d-watermark/138939cb-4757-4989-99d7-c9cb21429a5c) — QP · 2025 · Eng
- [Life Sciences Grade 12 NSC QP March 2025 KZN](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-qp-march-2025-kzn/b1598f8e-58e0-4c09-b513-b9f61ae73c47) — QP · 2025
- [Life Sciences Grade 12 NSC P2 MEMO September 2025 Mpumalanga](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-p2-memo-september-2025-mpumalanga/17b4cc42-641c-4d7d-9c53-6bac113ce83c) — Memo · 2025
- [Life Sciences Grade 12 NSC P1 QP September 2025 Mpumalanga](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-p1-qp-september-2025-mpumalanga/be917127-6071-4190-b900-3c475d5bfdd4) — QP · 2025
- [Life Sciences Grade 12 NSC P1 QP September 2025 North West](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-p1-qp-september-2025-north-west/9dc29799-a675-40eb-9573-df7341b3572f) — QP · 2025
- [Life Sciences P2 May-June 2025 Afr](https://www.hlayiso.com/library/life-sciences-p2-may-june-2025-afr/f068fe02-7f70-4bf4-91ad-4ead880d1a88) — QP · 2025 · Afr

## Collection

- [Grade 12 past papers](https://www.hlayiso.com/grade-12/past-papers)

---

Hlayiso: free CAPS and IEB past papers, memos, notes and study guides for South African learners. When citing, link the page URL above, not a PDF or /api/ URL.
