# Life Sciences Grade 12 P2 November 2024 NSC QP (Eng)

> Grade 12 Life Sciences Paper 2 question paper from the November 2024 NSC (English), 14 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/life-sciences-p2-nov-2024-eng/cfa1215b-7953-409b-99d9-8ffecbf4ab55
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Question paper
- Year: 2024
- Exam period: November 2024 NSC
- Paper: 2
- Curriculum: CAPS
- Pages: 14

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Life Sciences · Grade 12 · November 2024 NSC · 2024. Question paper, 14 pages. Read online or download the PDF.

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### Page 1

Confidential

                                GRAAD 12

                                NATIONAL
                           SENIOR CERTIFICATE

                                  GRADE 12

                               LIFE SCIENCES P2

                               NOVEMBER 2024

MARKS: 150

TIME: 2½ hours

                     This question paper consists of 14 pages.

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Life Sciences/P2                             2                             DBE/November 2024
                                       NSC Confidential

INSTRUCTIONS AND INFORMATION

Read the following instructions carefully before answering the questions.

1.        Answer ALL the questions.

2.        Write ALL the answers in the ANSWER BOOK.

3.        Start the answers to EACH question at the top of a NEW page.

4.        Number the answers correctly according to the numbering system used in this
          question paper.

5.        Present your answers according to the instructions of each question.

6.        Do ALL drawings in pencil and label them in blue or black ink.

7.        Draw diagrams, tables or flow charts only when asked to do so.

8.        The diagrams in this question paper are NOT necessarily drawn to scale.

9.        Do NOT use graph paper.

10.       You must use a non-programmable calculator, protractor and a compass,
          where necessary.

11.       Write neatly and legibly.

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Life Sciences/P2                              3                         DBE/November 2024
                                        NSC Confidential

SECTION A

QUESTION 1

1.1       Various options are provided as possible answers to the following questions.
          Choose the answer and write only the letter (A–D) next to the question
          numbers (1.1.1 to 1.1.10) in the ANSWER BOOK, e.g. 1.1.11 D.    Nov

          1.1.1      Which ONE of the following organelles is the site of protein
                     synthesis?

                     A   Ribosomes
                     B   Chloroplasts
                     C   Mitochondria
                     D   Centrosomes

          1.1.2      In humans, the gonosomes determine the gender.

                     Which combination below shows the CORRECT gonosomes for
                     males and females?

                            MALE GONOSOMES                 FEMALE GONOSOMES
                     A            XY                               YY
                     B            YY                               XY
                     C            XY                               XX
                     D            XX                               XY

          1.1.3      An organism has the genotype TT.

                     The CORRECT term which describes this organism's genotype
                     is …

                     A   heterozygous dominant.
                     B   heterozygous recessive.
                     C   homozygous dominant.
                     D   homozygous recessive.

          1.1.4      Down syndrome is a genetic disorder where an individual has an
                     extra copy of chromosome 21.

                     Which ONE of the following may lead to Down syndrome?

                     A   Failure of chromosomes to replicate during mitosis
                     B   Failure of chromosome pairs to separate during meiosis
                     C   Failure of chromosomes to form pairs during fertilisation
                     D   Failure of chromosome pairs to cross over during meiosis

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Life Sciences/P2                             4                          DBE/November 2024
                                       NSC Confidential

          1.1.5      A gradual change in the characteristics of a species over time is
                     known as …

                     A   punctuated equilibrium.
                     B   genetic engineering.
                     C   speciation.
                     D   biological evolution.

          1.1.6      Which ONE of the following is a reproductive isolation mechanism?

                     A   Adaptation to the same pollinator
                     B   Species-specific courtship behaviour
                     C   Production of fertile offspring
                     D   Breeding at the same time of the year

          1.1.7      Analysis of mitochondrial DNA is an example of this line of
                     evidence:

                     A   Fossil evidence
                     B   Modification by descent
                     C   Biogeography
                     D   Genetic evidence

          1.1.8      Which option in the table below shows the CORRECT comparison
                     between mitosis and meiosis?

                                      MITOSIS                        MEIOSIS
                     A     Produces four daughter cells   Produces two daughter cells
                     B     Produces genetically           Produces genetically
                           different cells                identical cells
                     C     The chromosome number          The chromosome number is
                           remains the same               halved
                     D     Two divisions occur            Four divisions occur

          1.1.9      Which ONE of the following scientists discovered the fossil Taung
                     Child?

                     A   Lee Berger
                     B   Ron Clarke
                     C   Raymond Dart
                     D   Robert Broom

          1.1.10     Which ONE of the following is produced at the end of translation?

                     A   A DNA molecule
                     B   A messenger RNA molecule
                     C   A protein
                     D   An amino acid                                          (10 x 2)       (20)

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Life Sciences/P2                                5                           DBE/November 2024
                                          NSC Confidential

1.2       Give the correct biological term for EACH of the following descriptions.
          Write only the term next to the question numbers (1.2.1 to 1.2.9) in the
          ANSWER BOOK.

          1.2.1        A nucleic acid that carries hereditary information

          1.2.2        The chromosome condition of a cell that has a single set of
                       chromosomes

          1.2.3        The structure that holds the two chromatids of a chromosome
                       together

          1.2.4        The type of RNA that carries specific amino acids to the site of
                       protein synthesis

          1.2.5        The analysis of DNA samples to identify individuals or relationships
                       between individuals

          1.2.6        A representation of the number and structure of all the
                       chromosomes that occur in the nucleus of a somatic cell

          1.2.7        A group of similar organisms that are able to interbreed to produce
                       fertile offspring

          1.2.8        The phase of meiosis where paired chromosomes are arranged at
                       the equator

          1.2.9        The biotechnological process that produces genetically identical
                       organisms                                                (9 x 1)            (9)

1.3       Indicate whether each of the descriptions in COLUMN I apply to A ONLY,
          B ONLY, BOTH A AND B or NONE of the items in COLUMN II. Write A only,
          B only, both A and B or none next to the question numbers (1.3.1 to 1.3.3)
          in the ANSWER BOOK.

                             COLUMN I                                 COLUMN II
          1.3.1      A source of variation in populations    A: Random fertilisation
                                                             B: Random mating
          1.3.2      Discovery of the structure of the       A: Franklin and Wilkins
                     DNA molecule                            B: Lamarck and Darwin
          1.3.3      Occurs during meiosis                   A: Karyokinesis
                                                             B: Cytokinesis
                                                                                       (3 x 2)     (6)

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Life Sciences/P2                               6                         DBE/November 2024
                                         NSC Confidential

1.4       The diagram below represents a DNA molecule undergoing an important
          biological process.

                                          1

                      2
                                     4
                                 3

                                                            5

          1.4.1      Identify the:

                     (a) Process shown in the diagram                                           (1)

                     (b) Chemical bond labelled 1                                               (1)

          1.4.2      Give the:

                     (a) Collective name for the parts labelled 2, 3 and 4                      (1)

                     (b) Full name of the nitrogenous base labelled 5                           (1)

          1.4.3      During which phase of the cell cycle does this process take place?         (1)

          1.4.4      Where in the cell does this process occur?                                 (1)
                                                                                                (6)

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Life Sciences/P2                            7                              DBE/November 2024
                                      NSC Confidential

1.5       In a certain species of butterfly, one gene controls wing-spot colour and
          another controls eye colour. The wing-spot colour can be red spots (R) or
          grey spots (r), while eye colour can be black (E) or brown (e).

          Butterflies that are heterozygous for both genes were crossed.

          1.5.1      Name the type of cross represented above.                                    (1)

          1.5.2      Give the dominant characteristic of EACH gene.                               (2)

          1.5.3      The table below shows the phenotypes and all the possible
                     genotypes of the offspring.

                            PHENOTYPES                   ALL POSSIBLE GENOTYPES
                      Red spots, brown eyes                         (X)
                                   (Y)                             RrEe
                      Grey spots, brown eyes                       rree

                     Give:

                     (a) ALL the possible genotypes at X                                          (4)

                     (b) The phenotype at Y                                                       (1)

                     (c) The genotype of the gametes produced by a butterfly with grey
                         spots and brown eyes                                                     (1)
                                                                                                  (9)

                                                                  TOTAL SECTION A:                50

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Life Sciences/P2                             8                              DBE/November 2024
                                       NSC Confidential

SECTION B

QUESTION 2

2.1       The diagram below represents a certain stage of protein synthesis.
          (The sequence of bases is read from left to right.)

                                                                             Strand 1
                                                                            (template)
              Molecule X                                                    Molecule Y

                               A G    A     U A C         C C A

                                               Z
                                                                            Strand 2

          2.1.1      Identify molecule Y.                                                          (1)

          2.1.2      Describe the process that resulted in the formation of molecule Y.            (6)

          2.1.3      Give ONE structural      difference between      molecule      X and
                     molecule Y.                                                                   (2)

          2.1.4      Give the sequence of bases at triplet Z on strand 2.                          (1)

          2.1.5      The table below shows some amino acids coded for by codons on
                     molecule Y.

                             CODON                   AMINO ACID
                              AGA                      Arginine
                              UCU                       Serine
                              CCA                      Proline
                              UAC                     Tyrosine
                              GGU                      Glycine

                     Identify the first and last amino acids coded for by this section of
                     molecule Y.                                                                   (2)
                                                                                                   (12)

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Life Sciences/P2                                 9                            DBE/November 2024
                                           NSC Confidential

2.2       The diagram below represents a phase of meiosis II.

                                                                       A

                                                                       B

          2.2.1      Identify the phase of meiosis shown.                                            (1)

          2.2.2      State ONE difference between the phase shown in the diagram
                     above and the same phase in meiosis I.                                          (2)

          2.2.3      Identify structure:

                     (a) A                                                                           (1)

                     (b) B                                                                           (1)

          2.2.4      Describe the role of structure B during cell division.                          (2)

          2.2.5      Draw a labelled diagram representing the cell above as it would
                     have appeared in metaphase II.

                     NOTE:     The diagram should show the correct shading and include
                               labels (exclude labels for A and B).                                  (5)
                                                                                                     (12)

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Life Sciences/P2                             10                             DBE/November 2024
                                        NSC Confidential

2.3       The table below shows the percentage of blood donors for each of the blood
          groups in South Africa for 2018.

                             BLOOD GROUP                   % DONORS
                                  O                           48
                                  A                           38
                                  B                           10
                                 AB                            4

          2.3.1      According to the data, which is the most common blood group
                     among the donors?                                                             (1)

          2.3.2      Name the type of dominance shown by the inheritance of blood
                     group A.                                                                      (1)

          2.3.3      Explain how it is possible for a man with blood group A and a
                     woman with blood group AB to have a child with blood group B.                 (5)

          2.3.4      Plot a bar graph to represent the data in the table.                          (6)
                                                                                                   (13)

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Life Sciences/P2                                     11                     DBE/November 2024
                                                NSC Confidential

2.4       Muscular dystrophy is a genetic condition that causes muscles to weaken
          over time. It is caused by a recessive allele on the X chromosome (Xd).
          The dominant allele (XD) results in normal muscle formation.

          The pedigree diagram below shows the inheritance of muscular dystrophy in
          a family.

                                            1               2

                                        3            4          5       6

                                                                7       8
                   Key:

                           Male without muscular dystrophy

                           Male with muscular dystrophy

                           Female without muscular dystrophy

                           Female with muscular dystrophy

          2.4.1           How many offspring do individuals 1 and 2 have?                          (1)

          2.4.2           Give the:

                          (a) Phenotype of individual 1                                            (1)

                          (b) Genotype of individual 2                                             (1)

          2.4.3           Explain why more males than females are likely to have muscular
                          dystrophy.                                                               (4)

          2.4.4           Parents 5 and 6 plan to have another child.

                          Use a genetic cross to show the percentage chance of having
                          a child with muscular dystrophy.                                         (6)
                                                                                                   (13)
                                                                                                   [50]

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Life Sciences/P2                                   12                                                        DBE/November 2024
                                              NSC Confidential

QUESTION 3
3.1       Read the passage below.

                                   GENETICALLY MODIFIED MAIZE
          The bacterium Bacillus thuringiensis produces a toxin, called Bt, that kills
          insects. This bacterium is used to genetically modify maize to contain the
          Bt toxin. This Bt maize is toxic to insects.

          3.1.1      Describe how the Bt maize is genetically modified to be insect
                     resistant.                                                                                                      (3)
          3.1.2      Explain TWO reasons why farmers might want to grow Bt maize.                                                    (4)
                                                                                                                                     (7)
3.2       The phylogenetic tree below shows the evolutionary relationship between
          some species.

                                                                                   P

                                                            Chimpanzees
                                               Humans
                                                                                         Orangutans
                       New-world
                                    Gibbons
                                                                                                      Old-world
                        monkeys                                               Gorillas
                                                                                                      monkeys

                                                        Q
                                                            R
                                                                          S
                                                            T
                                                                          U
                                                            V

          3.2.1      Give the LETTER representing the common ancestor for ALL the
                     species shown in the phylogenetic tree.                                                                         (1)

          3.2.2      Identify the species that is most closely related to Old-world
                     monkeys.                                                                                                        (1)
          3.2.3      Give a reason for your answer to QUESTION 3.2.2.                                                                (1)

          3.2.4      Identify THREE species that share the common ancestor R.                                                        (3)
          3.2.5      State THREE characteristics of the upper limbs that humans share
                     with group P.                                                                                                   (3)
                                                                                                                                     (9)

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Life Sciences/P2                             13                           DBE/November 2024
                                        NSC Confidential

3.3       A group of researchers conducted an investigation to determine the influence
          of the type of milk on the height of children drinking the milk. (The
          investigation was conducted over a period of 7 years from age 3 to age 10).

          They:
          -  Selected 4 146 healthy 3-year-old children of the same race and gender
          -  Divided the children into two equal groups:
              One group was given 1 litre of cow's milk to drink daily
              The other group was given 1 litre of soy milk to drink daily
          -  Ensured that each group had:
              The same additional diet
              Similar daily activities
              Similar living conditions
          -  Provided the milk from the same supplier
          -  Measured the children's height at the end of the investigation and
             calculated the average

          The table below shows the results at the end of the investigation compared to
          the expected average height of 10-year-olds.

                EXPECTED                AVERAGE HEIGHT               AVERAGE HEIGHT
             AVERAGE HEIGHT              OF A CHILD ON              OF A CHILD ON SOY
                 OF CHILD                 COW'S MILK                      MILK
                   (cm)                       (cm)                         (cm)
                  149,86                     151,4                        147,4

          3.3.1      Identify the:

                     (a) Independent variable                                                    (1)

                     (b) Dependent variable                                                      (1)

          3.3.2      Name the type of variation displayed by the height of a person.             (1)

          3.3.3      State TWO planning steps that the researchers had to consider at
                     the beginning of this investigation.                                        (2)

          3.3.4      State THREE ways in which the validity of this investigation was
                     ensured.                                                                    (3)

          3.3.5      State ONE factor that could have negatively affected the validity of
                     this investigation.                                                         (1)

          3.3.6      How did the researchers ensure the reliability of the results?              (1)

          3.3.7      State the conclusion for this investigation.                                (2)
                                                                                                 (12)

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Life Sciences/P2                           14                          DBE/November 2024
                                      NSC Confidential

3.4       The passage below describes Homo erectus fossils.

          Evidence from fossils of Homo erectus shows that they appeared in Africa
          about 2 million years ago. They spread to many parts of Asia. Homo erectus
          is the oldest known species to be fully bipedal and have a human-like body.
          Their brain size was smaller than that of humans today. A prominent brow
          ridge was present over their eye sockets.

          3.4.1      Describe how the fossils of Homo erectus are used to support the
                     'Out-of-Africa' hypothesis.                                           (3)

          3.4.2      Describe how all OTHER fossil evidence is used to support the
                     'Out-of-Africa' hypothesis.                                           (4)

          3.4.3      Use the information in the passage regarding Homo erectus and
                     tabulate TWO differences between the features of Homo erectus
                     and Homo sapiens.                                                     (5)

          3.4.4      What observation of the skull of Homo erectus would have led
                     scientists to conclude that Homo erectus was bipedal?                 (1)
                                                                                           (13)

3.5       Read the passage below.

                              NATURAL SELECTION IN WOLVES

          In 1986 there was a huge radioactive disaster in Chernobyl and all humans
          immediately left the area because of the deadly high radiation. Animals
          exposed to this high radiation developed cancer or died. Almost 40 years
          later, scientists have been studying the wolves that live in this highly
          radioactive environment where they are exposed to high radiation. They found
          that these wolves have a mutation that makes them immune to cancer.

          3.5.1      What is a mutation?                                                   (1)

          3.5.2      What effect does exposure to high radiation have on animals?          (1)

          3.5.3      Use Darwin's theory of natural selection to          explain   the
                     development of immunity to cancer in these wolves.                    (7)
                                                                                           (9)
                                                                                           [50]

                                                                 TOTAL SECTION B:          100
                                                                    GRAND TOTAL:           150

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