# Life Sciences Grade 12 P2 November 2024 NSC Memo (English)

> Grade 12 Life Sciences Paper 2 memorandum from the November 2024 NSC (English), 11 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/life-sciences-p2-nov-2024-mg-eng/c846a9cb-3f40-45d0-a818-427273a170fb
- Updated: 2026-10-29
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Memorandum
- Year: 2024
- Exam period: November 2024 NSC
- Paper: 2
- Curriculum: CAPS
- Pages: 11

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## About this document

Life Sciences · Grade 12 · November 2024 NSC · 2024. Memorandum. Read online or download the PDF.

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### Page 1

NATIONAL
                             SENIOR CERTIFICATE

                                     GRADE 12

                                 LIFE SCIENCES P2

                                  NOVEMBER 2024

                          MARKING GUIDELINES
               FINAL MARKING GUIDELINES - 25 November 2024

MARKS: 150

                     These marking guidelines consist of 11 pages.

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### Page 2

Life Sciences/P2                               2                           DBE/November 2024
                                    NSC – Marking Guidelines

 PRINCIPLES RELATED TO MARKING LIFE SCIENCES

 1.        If more information than marks allocated is given
           Stop marking when maximum marks are reached and put a wavy line and 'max'
           in the right-hand margin.

 2.        If, for example, three reasons are required and five are given
           Mark the first three irrespective of whether all or some are correct/incorrect.

 3.        If whole process is given when only a part of it is required
           Read all and credit the relevant part.

 4.        If comparisons are asked for, but descriptions are given
           Accept if the differences/similarities are clear.

 5.        If tabulation is required, but paragraphs are given
           Candidates will lose marks for not tabulating.

 6.        If diagrams are given with annotations when descriptions are required
           Candidates will lose marks.

           If flow charts are given instead of descriptions
 7.        Candidates will lose marks.

 8.        If sequence is muddled and links do not make sense
           Where sequence and links are correct, credit. Where sequence and links are
           incorrect, do not credit. If sequence and links become correct again, resume
           credit.

 9.        Non-recognised abbreviations
           Accept if first defined in answer. If not defined, do not credit the unrecognised
           abbreviation, but credit the rest of the answer if correct.

 10.       Wrong numbering
           If answer fits into the correct sequence of questions, but the wrong number is
           given, it is acceptable.

 11.       If language used changes the intended meaning
           Do not accept.

 12.       Spelling errors
           If recognisable, accept the answer, provided it does not mean something else
           in Life Sciences or if it is out of context.

 13.       If common names are given in terminology
            Accept, provided it was accepted at the national standardisation meeting.

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### Page 3

Life Sciences/P2                               3                           DBE/November 2024
                                    NSC – Marking Guidelines

 14.       If only the letter is asked for, but only the name is given (and vice versa)
           Do not credit.

 15.       If units are not given in measurements
           Candidates will lose marks. The marking guideline will allocate marks for units
           separately.

 16.       Be sensitive to the sense of an answer, which may be stated in a different
           way.

 17.       Caption
           All illustrations (diagrams, graphs, tables, etc.) must have a caption.

 18.       Code-switching of official languages (terms and concepts)
           A single word or two that appear(s) in any official language other than the
           learner's assessment language used to the greatest extent in his/her answers
           should be credited, if it is correct. A marker that is proficient in the relevant
           official language should be consulted. This is applicable to all official
           languages.

 19.       Changes to the marking guideline
           No changes must be made to the marking guidelines. The provincial internal
           moderator must be consulted, who in turn will consult with the national internal
           moderator (and the Umalusi moderators where necessary).

 20.       Official marking guidelines
           Only marking guidelines bearing the signatures of the national internal
           moderator and the Umalusi moderators and distributed by the National
           Department of Basic Education via the provinces must be used.

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### Page 4

Life Sciences/P2                              4                  DBE/November 2024
                                   NSC – Marking Guidelines

 SECTION A

 QUESTION 1

 1.1       1.1.1     A✓✓
           1.1.2     C✓✓
           1.1.3     C✓✓
           1.1.4     B✓✓
           1.1.5     D✓✓
           1.1.6     B✓✓
           1.1.7     D✓✓
           1.1.8     C✓✓
           1.1.9     C✓✓
           1.1.10    C✓✓                                                  (10 x 2)    (20)

 1.2       1.2.1     Deoxyribonucleic acid✓/DNA
           1.2.2     Haploid✓
           1.2.3     Centromere✓
           1.2.4     transfer RNA✓/tRNA
           1.2.5     DNA profiling✓
           1.2.6     Karyotype✓/karyogram
           1.2.7     Species✓
           1.2.8     Metaphase I✓/1
           1.2.9     Cloning✓                                               (9 x 1)   (9)

 1.3       1.3.1     Both A and B✓✓
           1.3.2     A only✓✓
           1.3.3     Both A and B✓✓                                         (3 x 2)   (6)

 1.4       1.4.1     (a) (DNA) replication✓                                           (1)
                     (b) Hydrogen✓bond                                                (1)

           1.4.2     (a) Nucleotide✓                                                  (1)
                     (b) Thymine✓                                                     (1)

           1.4.3     Interphase✓                                                      (1)

           1.4.4     Nucleus✓                                                         (1)
                                                                                      (6)

 1.5       1.5.1     Dihybrid✓ cross                                                  (1)

           1.5.2     Red spots✓ and black eyes✓                                       (2)

           1.5.3     (a) RRee✓✓ and Rree✓✓                                            (4)
                     (b) Red spots, black eyes ✓                                      (1)
                     (c) re✓                                                          (1)
                                                                                      (9)
                                                              TOTAL SECTION A:        50

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### Page 5

Life Sciences/P2                                5                     DBE/November 2024
                                     NSC – Marking Guidelines

 SECTION B
 QUESTION 2
 2.1       2.1.1     mRNA✓/messenger RNA                                                  (1)

           2.1.2     -   The DNA double helix unwinds✓ and
                     -   (the double strand) unzips✓/(weak) hydrogen bonds break
                     -   to form two separate strands✓
                     -   One strand is used as a template✓
                     -   to form mRNA✓
                     -   using free RNA nucleotides✓ from the nucleoplasm
                     -   The mRNA is complementary to the DNA✓/ A complements U,
                         G complements C                                         Any      (6)

           2.1.3     -  Molecule X (DNA) is double stranded✓(double helix)
                     -  Molecule Y (RNA) is single stranded✓
                                                   OR
                     - Molecule X (DNA) has H-bonds✓
                     - Molecule Y (RNA) has no H-bonds✓
                                                   OR
                     - Molecule X (DNA) contains deoxyribose✓sugar
                     - Molecule Y (RNA) contains ribose✓sugar
                                                   OR
                     - Molecule X (DNA) has thymine✓/T as a nitrogenous base
                     - Molecule Y (RNA) has uracil✓/U as a nitrogenous base
                                                   OR
                     - Molecule X (DNA) is longer✓
                     - Molecule Y (RNA) is shorter✓
                     (Mark first ONE only)                                 Any (1 x 2)    (2)

           2.1.4     TAC✓                                                                 (1)

           2.1.5     -   Arginine✓
                     -   Proline✓                                                         (2)
                                                                                          (12)

 2.2       2.2.1     Anaphase II✓                                                         (1)

           2.2.2     -  Chromosome pairs separate during Anaphase I✓/
                        chromosomes move to the poles
                     - A chromosome separates during Anaphase II✓/chromatids
                        move to the poles
                                                   OR
                     - Centromeres do not split during Anaphase I✓
                     - Centromeres split during Anaphase II✓
                     (Mark first ONE only)                            Any (1 x 2)         (2)

           2.2.3     (a) Centriole✓/centrosome                                            (1)

                     (b) Spindle fibre✓                                                   (1)

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Life Sciences/P2                              6                        DBE/November 2024
                                   NSC – Marking Guidelines

           2.2.4     -    Attaches to the centromere✓
                     -    to pull chromatids/chromosomes towards the (opposite) poles✓
                                                      OR
                     -    it contracts✓/shortens
                     -    to pull chromatids/chromosomes towards the (opposite) poles✓       (2)

           2.2.5                      Diagram showing metaphase II

                                                                  Cell membrane

                                                                  Cytoplasm

                                                                  Chromosome

                                                                  Centromere

                                                                  Chromatid

          Guideline for assessing the drawing

                                      Criteria                                 Marks
           Position: chromosomes in a single row at the equator     (P)           1
           Number: 2 unpaired chromosomes drawn                     (N)           1
           Shading of chromosomes                                   (S)           1
           1 shaded chromosome with an unshaded tip
           1 unshaded chromosome with a shaded tip
           Any TWO correct labels                                   (L)           2
           (except centriole & spindle fibre)                                                (5)
                                                                                             (12)

 2.3       2.3.1     O✓                                                                      (1)

           2.3.2     Complete✓dominance                                                      (1)

           2.3.3     -   The man is heterozygous✓ /is IAi for blood group A
                     -   The woman has an allele for blood group B✓/is IAIB
                     -   The child inherits the IB allele from the mother✓
                     -   and the i allele from the father✓
                     -   Therefore, the child will be heterozygous✓ for blood group B/
                         the genotype will be IBi                                            (5)

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### Page 7

Life Sciences/P2                                      7                           DBE/November 2024
                                           NSC – Marking Guidelines

           2.3.4

                         The percentage of blood donors for different blood groups
                      60                 in South Africa for 2018
                               48
                      50
                                               38

           % Donors
                      40
                      30
                      20
                                                                       10
                      10                                                                 4
                       0
                                  O                 A                  B                AB
                                                        Blood groups

        Guideline for assessing the graph
                    CRITERIA                                   ELABORATION                       MARK
          Correct type of graph              (T)   Bar graph drawn                                 1
          Caption of graph                  (C)    Both variables, SA and 2018 included            1
          Axes labels                       (L)    X- and Y axis correctly labelled with units     1
          Scale for X- and Y-axis            (S)   - Equal space and width of bars for
                                                      X-axis and                                      1
                                                   - Correct scale for Y-axis
          Plotting of co-ordinates           (P)   - 1 to 3 co-ordinates plotted correctly            1
                                                   - All 4 co-ordinates plotted correctly             2

           Histogram or line graph drawn                                                                  (6)
           - Lose marks for type of graph and for scale                                                   (13)

           Transposed axes:
           - Can get full credit, if axes labels are also swapped and bars are horizontal
           - If labels are not corresponding, then lose marks for labels and scale
           - Check that the plotting is correct for the given labels

 2.4        2.4.1              Three✓/3                                                                   (1)

           2.4.2               (a) Male without muscular dystrophy✓                                       (1)

                               (b) XDXd✓                                                                  (1)

           2.4.3           -   Males only have one X chromosome✓/XY and
                           -   need only one recessive allele to have muscular dystrophy✓
                           -   The Xd allele on a male cannot be masked by a dominant allele✓
                           -   Females have two X-chromosomes✓ and
                           -   need two recessive alleles to have muscular dystrophy✓/ XdXd
                           -   In females, a dominant allele on one X chromosome would mask
                               the effect of the recessive allele✓/XD masks Xd             Any            (4)

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### Page 8

Life Sciences/P2                                8                                 DBE/November 2024
                                     NSC – Marking Guidelines

           2.4.4     P2               Phenotype      Female without               Male without
                                                     muscular                     muscular
                                                                              x
                                                     dystrophy                    dystrophy✓

                                      Genotype       XDXd                     x   XDY✓
                     Meiosis
                                      Gametes          X D,     Xd            x       X D,   Y✓

                     Fertilisation

                     F2               Genotype        XD XD           XD Y,       XD Xd,     XdY ✓

                                      Phenotype      (50%) females without muscular dystrophy
                                                     (25%) male without muscular dystrophy    ✓
                                                     (25%) male with muscular dystrophy

                                                     25✓*% chance of muscular dystrophy child
                     P2 and F2✓
                     Meiosis and fertilisation✓
                                                                     *1 compulsory mark + Any 5
                                                              OR
                     P2                Phenotype     Female without               Male without
                                                     muscular                     muscular
                                                                              x
                                                     dystrophy                    dystrophy✓

                                       Genotype      XDXd                     x   XDY✓

                     Meiosis
                                                       Gametes                  XD            Xd
                     Fertilisation                        XD                  XD XD          XD Xd
                                                           Y                  XD Y            XdY

                                                     1 mark for correct gametes
                                                     1 mark for correct genotypes

                     F2                Phenotype     (50%) females without muscular dystrophy
                                                     (25%) male without muscular dystrophy ✓
                                                     (25%) male with muscular dystrophy

                                                     25✓*% chance of muscular dystrophy child
                     P2 and F2✓
                     Meiosis and fertilisation✓
                                                                       *1 compulsory mark + Any 5     (6)
                                                                                                      (13)
                                                                                                      [50]

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### Page 9

Life Sciences/P2                              9                        DBE/November 2024
                                   NSC – Marking Guidelines

 QUESTION 3

 3.1       3.1.1     -    The Bt producing gene is cut from the bacterial DNA✓ and
                     -    inserted into maize DNA✓
                     -    This recombinant DNA✓
                     -    causes the maize plant to produce the Bt toxin✓          Any     (3)

           3.1.2     -  Fewer crops damaged✓
                        leads to increased yield✓/more food for people/increased food
                        security/healthier crops/more profit
                     - Reduced need for pesticides,✓
                        farmers save money✓/less toxins to consumers/environment
                     (Mark first TWO only)                                     (2 x 2)     (4)
                                                                                           (7)

 3.2       3.2.1     V✓                                                                    (1)

           3.2.2     Gibbons✓/U                                                            (1)

           3.2.3     For gibbons at 3.2.2
                     They share the most recent common ancestor U✓
                                                     OR
                     For ‘U’ at 3.2.2
                     Old-world monkeys are directly descended from U✓                      (1)

           3.2.4     Humans✓
                     Chimpanzees✓
                     Gorillas✓
                     Q✓                                                            Any     (3)
                     (Mark first THREE only)

           3.2.5     - (Freely) rotating arms✓
                     - Long upper arms✓
                     - Rotation around the elbow joints✓
                     - Rotation around the wrist✓
                     - Bare fingertips✓
                     - Nails instead of claws✓
                     - Have fingerprints✓
                     - Opposable thumb✓/Precision grip
                     - Five digits per limb✓/Pentadactyl hand                      Any     (3)
                     (Mark first THREE)                                                    (9)

 3.3       3.3.1     (a) Type of milk✓                                                     (1)

                     (b) Height✓ of children                                               (1)

           3.3.2     Continuous✓ (variation)                                               (1)

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Life Sciences/P2                            10                         DBE/November 2024
                                  NSC – Marking Guidelines

           3.3.3     - Ensure the same additional diet✓
                     - Ensure similar daily activities✓
                     - Ensure similar living conditions✓
                     - Date✓ /time/ venue for measurement
                     - Decide on the sample size✓
                     - Ask for parental consent✓
                     - Train the research assistants✓
                     - Recruit parents that are willing to participate✓
                     - Decide on the target group✓
                     - Design the recording sheet✓
                     - Decide on the source of milk✓
                     - Select apparatus✓ /equipment/decide on method measurement
                     - Decide on duration✓ of investigation
                     - Choosing the type of milk✓
                     - Decide on the amount of milk✓                         Any           (2)
                     (Mark first TWO only)
           3.3.4     - Only healthy children✓ chosen
                     Same:
                     - age✓
                     - race✓
                     - gender✓
                     - quantity of milk✓
                     - additional diet✓
                     - supplier of milk✓
                     - number of children in each group✓
                     - duration✓
                     Similar:
                     - daily activities✓
                     - living (environmental) conditions✓                            Any   (3)
                     (Mark first THREE only)
           3.3.5     - Genetic/hormonal influence was not considered✓
                     - Difficult to maintain the same conditions over a 7-year period✓
                     - Not measuring the baseline height✓                           Any    (1)
                     (Mark first ONE only)
           3.3.6     -   2 073 children in each group✓ participated
                     -   4 146 children divided into two equal groups✓ participated
                     -   Investigation conducted over 7 years✓                      Any    (1)
           3.3.7     Cow milk consumption leads to better growth/increased height
                     compared to soy milk✓✓
                                                  OR
                     Soy milk consumption by children leads to decreased height✓✓/
                     below average height
                                                  OR
                     Cow-milk consumption by children leads to increased height✓✓/
                     above average height                                                  (2)
                                                                                           (12)

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### Page 11

Life Sciences/P2                             11                           DBE/November 2024
                                   NSC – Marking Guidelines

 3.4       3.4.1     -   The oldest fossils of Homo erectus were found in Africa✓, while
                     -   the younger fossils were found in other parts of the world✓/Asia
                     -   indicating that Homo erectus migrated out of Africa✓                 (3)

           3.4.2     -   Ardipithecus fossils were found in Africa only✓
                     -   Australopithecus fossils were found in Africa only✓
                     -   Fossils of Homo habilis were found in Africa only✓
                     -   The oldest fossils of Homo sapiens were found in Africa✓
                     -   The younger fossils of Homo sapiens were found in other parts
                         of the world✓                                            Any         (4)

           3.4.3           Homo erectus                   Homo sapiens
                           Small brain✓                   Large brain✓
                           Prominent brow ridges✓         Reduced brow ridges✓
                     (Mark first TWO)                                (2 x 2) + (1) table ✓    (5)

           3.4.4     The foramen magnum was in a (more) forward position✓                     (1)
                                                                                              (13)

 3.5       3.5.1     Changes in the genetic composition✓ of organisms                         (1)

           3.5.2     Leads to cancer✓/death/mutations                                         (1)

           3.5.3     -   There was variation amongst (the population of) the wolves✓
                     -   Some had the mutation which made them immune to cancer and
                         some did not✓
                     -   When exposed to radiation✓
                     -   the wolves without the mutation/immunity died✓
                     -   Those with the mutation/ immunity survived✓
                     -   and reproduced✓
                     -   passing the allele for the mutation/ immunity to their offspring✓
                     -   The next generation had a higher proportion of wolves with the
                         mutation✓/immunity to cancer                                   Any   (7)
                                                                                              (9)
                                                                                              [50]

                                                                     TOTAL SECTION B:         100
                                                                        GRAND TOTAL:          150

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