# Life Sciences Grade 12 Paper 2 Limpopo Mock 2022 Memo

> Grade 12 Life Sciences Paper 2 memorandum from the Limpopo Mock Exam 2022, 29 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/limpopo-life-sciences-grade-12-sept-2022-p2-and-memo/a14d1ac1-f20f-44b6-9531-44480fcf1d4c
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Memorandum
- Year: 2022
- Exam period: Limpopo Mock Exam
- Paper: 2
- Curriculum: CAPS
- Pages: 29

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                          GRADE 12

                     LIFE SCIENCES P2
                     SEPTEMBER 2022
         PREPARATORY EXAMINATION
             PREPARATORY EXAMINATION

MARKS:150
TIME: 2½ HOURS

             This question paper consists of 17 pages.

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 INSTRUCTIONS AND INFORMATION

 Read the following instructions carefully before answering the questions.

 1.        Answer ALL the questions.

 2.        Write ALL the answers in your ANSWER BOOK.

 3.        Begin the answers to each question at the top of a NEW page.

 4.        Number the answers correctly according to the numbering system used in this
           question paper.

 5.
                                                                     s.co
           Present your answers according to the instructions of each question.

 6.
                                                                         m
           ALL drawings should be done in pencil and labelled in blue or black ink.
                                                                si c
 7.        Only draw diagrams or flow charts when asked to do so.
                                         st
 8.                                         an
           The diagrams in this question paper are NOT all drawn to scale.

 9.        Do NOT use graph paper.
                                              mor
 10.                                              ep
           Non-programmable calculators, protractors and compasses may be used.

 11.       Write neatly and legibly.
                                                    hy
                                       om
                                fr
                       oa
                         de
                           d
           do
             wn
               l

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 SECTION A

 QUESTION 1

 1.1       Various options are provided as possible answers to the following questions.
           Choose the correct answer and write only the letter (A–D) next to the question
           number (1.1.1 to 1.1.10) in your ANSWER BOOK, for example
           1.1.11 D.

           1.1.1       The sequence of nitrogenous bases UCA CGA ACC GCU AAC
                       could represent ...

                       A   a gene that codes for one protein.
                       B   a DNA strand that codes for one mRNA molecule.
                       C
                       D
                           a chain of five amino acids.                 s.
                           an mRNA strand that codes for five amino acids.co
          1.1.2        A male who is homozygous for blood group A and a
                                                                            m
                                                                  si
                       female with blood group B have children. Which ONE of
                                                                     c
                       the following genotypes is possible in the offspring?
                                           st
                       A   IA IA              an
                       B
                       C
                           IA i
                           ii
                                                mor
                       D   IB i                     ep
          1.1.3                                       hy
                       Colour blindness is a sex-linked trait and is caused by a
                       recessive allele on the X chromosome. The pedigree diagram
                                     om
                       below shows the inheritance of colour blindness in a family.

                                   fr                        KEY:

                       oa                                         Normal male
                         de                                         Affected male
                           d                                        Normal female
           do                                                       Affected female
             wn
               l
                       Persons I and II have a child. What is the chance that the child will
                       be colour-blind?

                       A   0%
                       B   25%
                       C   75%
                       D   100%

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           1.1.4       The diagrams below show the forelimbs of some
                       vertebrates

                        The type of evidence for evolution represented is...

                        A   fossil evidence
                        B   biogeography.
                        C   modification by descent
                        D   genetic evidence

           1.1.5        The diagram below shows a karyotype of a human.
                        Which statement about this karyotype is correct?

                        A   Non-disjunction has occurred, and the individual is male.
                        B   Non-disjunction has not occurred, and the individual is female.
                        C   Non-disjunction has not occurred, and the individual is male.
                        D   Non-disjunction has occurred, and the individual is female.

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           1.1.6       Changes to the genetic material of organisms can ONLY be
                       inherited by the next generation if they ...

                       A     occur in somatic cells.
                       B     increase the survival chances of the species.
                       C     occur in reproductive cells.
                       D     increase the survival chances of an individual.

           1.1.7       Below is a list of fossils discovered in South Africa:

                       1.   Taung child
                       2.   Little Foot
                       3.   Karabo
                       4.   Mrs Ples

                       Which of the fossils above are classified in the genus
                       Australopithecus?

                       A     1, 2 and 3
                       B     1, 2, 3 and 4
                       C     2, 3 and 4
                       D     1, 3 and 4

           1.1.8       DNA from the cells of an animal was analysed in a laboratory.
                       The results are shown in the table below.

                                          Nitrogenous Base Composition
                               X            Guanine           Y                     Z
                             23,4%            26,3%         26,7%                 23,6%

                       Which of the following is a possible correct identification of the
                       bases X, Y and Z?

                                      X                     Y                      Z
                       A           cytosine              adenine                thymine
                       B           thymine               adenine                cytosine
                       C           adenine               cytosine               thymine
                       D           cytosine              thymine                adenine

           1.1.9       When red shorthorn cattle are crossed with white shorthorn cattle,
                       the offspring have both red and white fur. This cross is an example
                       of…..

                       A     Inheritance with multiple alleles
                       B     Incomplete dominance
                       C     Dihybrid cross
                       D     Co-dominance
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           1.1.10      The diagram below shows the genotypes of two parent plants and
                       three of their offspring for a characteristic that is controlled by a
                       dominant allele.

                           Parents          Plant 1                       Plant 2
                                              Rr                            Rr

                       Offspring            Plant 3        Plant 4        Plant 5
                                             RR              Rr             rr

                       Which of the plants have the same phenotype?

                       A    1, 2 and 4
                       B    1, 2, 3 and 4
                       C    3 and 5
                       D    3, 4 and 5
                                                                                         (10 x 2)   (20)

 1.2       Give the correct biological term for each of the following descriptions. Write
           only the term next to the question number (1.2.1 to 1.2.8) in your ANSWER
           BOOK.

           1.2.1       A factor/variable that is changed or manipulated during an
                       investigation

           1.2.2       The law that describes how alleles are separated from one another
                       during the formation of gametes

           1.2.3       A genotype consisting of different alleles for a specific trait

           1.2.4       The complete disappearance of a species from earth

           1.2.5       The splitting of the cytoplasm during cell division

           1.2.6       An opening on hominid skulls through which the spinal cord passes

           1.2.7       The region of a chromosome where two chromatids are attached to
                       each other
                                                                                                    (7)

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 1.3      Indicate whether each of the statements in COLUMN 1 applies to
          A ONLY, B ONLY, BOTH A AND B or NONE of the items in COLUMN 2.
          Write A only, B only, both A and B, or none next to the question number
          (1.3.1 to 1.3.8) in the ANSWER BOOK.

                         COLUMN 1                                 COLUMN 2
           1.3.1 Genetic disorder linked to a sex      A     Haemophilia
                 chromosome                            B     Sickle-cell anaemia
           1.3.2 The evidence used to support the      A     Mitochondrial DNA
                 “Out of Africa” hypothesis by         B     Y-chromosome
                 tracing the maternal lineage
           1.3.3 Examples of reproductive              A  Breeding at different
                 isolation mechanisms                     times of the year
                                                   B      Adaptation to different
                                                          pollinators
                                                                                 (3 x 2)      (6)
 1.4       The diagram below shows a process that occurs during meiosis.                      •

           1.4.1       Name:
                       (a) the process occurring in the diagram above.                        (1)

                       (b) the phase in meiosis during which this process occurs.             (1)

           1.4.2       Identify the part marked Y.                                            (1)

           1.4.3       Describe the process mentioned in QUESTION 1.4.1 (a).                  (3)
                                                                                              (6)

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 1.5       In cattle, black coat colour (B) is dominant to brown coat colour (b), and long
           horns (H) are dominant over short horns (h).

           Study the following Punnett square of the cross between a cow and a bull
           before answering the questions that follow.

            FEMALE →                 BH             Bh              bH                   bh
            MALE   ↓
               Bh                     X

                     Bh                              Y

                     Bh

                     Bh

           1.5.1          State why the example above represents a dihybrid cross.               (2)

           1.5.2          Give the genotype of the female parent                                 (1)

           1.5.3          Give the:
                             (a) genotype of offspring X                                         (2)
                             (b) phenotype of offspring Y                                        (2)

           1.5.4          What percentage of the offspring will be black with long horns?
                          Show your working out.                                                 (3)

           1.5.5          Which principle of Mendel applies to dihybrid crosses only?            (1)

                                                                                                 (11)
                                                                                                 [50]

                                                                         TOTAL SECTION A:        50

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 SECTION B
 QUESTION 2

 2.1       The diagram below shows different phases of meiosis in an organism.

                                                                               Y

                                                 X
                                  Diagram
                                  Diagram I1                 DiagramII2
                                                             Diagram

                                                                           M
                              Z
                                                DiagramIII
                                               Diagram   3

           2.1.1     Identify structure:

                        (a) X                                                                   (1)

                        (b) Z.                                                                  (1)

           2.1.2     Give TWO observable reasons why chromosomes pair Y is regarded
                     as being homologous.                                                       (2)

           2.1.3     Identify the phases shown in diagrams 1, 2 and 3.                          (3)

           2.1.4     List TWO events in meiosis that contribute to genetic variation.           (2)
                                                                                                (9)

   2.2     A blue-eyed woman marries a man who is heterozygous for brown eyes.
           Brown eyes (B) are dominant over blue eyes (b).

           Use a genetic cross to show the possible genotypes and phenotypes of their
           children.                                                                            (6)

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 2.3 The pedigree diagram below shows the inheritance of a genetic disease
     caused by a single gene.

                                     1         2

                 3        4                              5

                 KEY
                              Unaffected                 Unaffected
                              male                       female

                              Affected male              Affected female

        2.3.1 Use individuals 2 and 5 to explain why this disease is a caused by a
              recessive allele on the X-chromosome.                                     (5)

        2.3.2 Use the letters Xn for the recessive allele and XN for the dominant
              allele to give the genotypes of individual:

                (a) 3                                                                   (1)

                (b) 4                                                                   (1)

        2.3.3 What percentage of the daughters produced by individuals 3 and 4
              would be affected?                                                        (1)
                                                                                        (8)

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 2.4       A group of grade 12 learners conducted a survey to establish the number
           of learners with each blood group.
           The graph below shows the results of the survey.
                                                  Percentage of learners with each blood group
                                        50
                                        45

           Percentage of learners (%)
                                        40
                                        35
                                        30
                                        25
                                        20
                                        15
                                        10
                                        5
                                        0
                                                  A               B           AB                  O
                                                                   Blood groups
                                                                   Blood groups

           2.4.1                              State TWO planning steps that should be considered before
                                              carrying out this investigation                                   (2)

           2.4.2                              Which blood group has the lowest percentage of learners?          (1)

           2.4.3                              Give ONE reason why the data from this investigation was
                                              represented using the above type of graph.                        (2)

           2.4.4                              What conclusion can be drawn from the results presented in
                                              the graph?                                                        (2)

           2.4.5                              The frequency of each blood group worldwide is shown in the
                                              table below
                                                       Blood type         Worldwide Frequency (%)
                                                           O                        45
                                                           A                        40
                                                           B                        11
                                                           AB                        4

                                              The learners expected their results to correspond with the
                                              results in the table, but they do not.
                                              Explain why the results of the learners’ investigation are not
                                              reliable.                                                         (2)
                                                                                                                (9)

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 2.5       The table below shows the skulls of fossils of different genera.
               GENERA                 SKULL             BRAIN            PERIOD OF
                                                       VOLUME           EXISTENCE
                                                                      (MILLION YEARS
                                                                           AGO)
           African ape                                 530 cm³     8 mya

           Australopithecus                            430cm³      4–2,7 mya

           Homo erectus                                850cm³      2–0,4 mya

           Homo sapiens                                1450cm³     0,2 mya–present

           2.5.1       How many million years ago did Homo erectus first appear?              (1)

           2.5.2       Calculate the difference in brain volume between Australopithecus
                       and Homo sapiens. Show ALL calculations.                               (2)

           2.5.3       State TWO advantages of a larger brain volume.                         (2)

           2.5.4       Tabulate THREE visible differences between the skulls of Homo
                       sapiens and the African ape.                                           (7)

           2.5.5       Describe TWO structural features of the body that correspond with
                       the evolution to bipedalism.                                           (4)
                                                                                              (16)

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 2.6       Genetically modified organisms (GMOs) bring new hope for medical cures,
           promise to increase yields in agriculture and have the potential to help solve
           the world's pollution and resource crisis.
           There are also many objections to GMOs, some stating that they are expensive
           to produce and are a threat to biodiversity.

           2.6.1       Give ONE reason why:

                       (a) the initial cost of production of GMOs is high                       (1)

                       (b) GMOs are considered a threat to biodiversity                         (1)

                                                                                                (2)

                                                                     TOTAL QUESTION 2:          [50]

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  QUESTION 3

  3.1      Read the extract.

           Scientists have studied the appearance, genetics and behaviours of wolves
           and domesticated dogs to better understand what caused them to diverge
           thousands of years ago. Wolves began to evolve through a process in which
           people selectively bred individuals with desired traits and behaviours, such
           as reduced aggression and willingness to submit to human social structure.
           Scientists have discovered that some wolves had the genes to produce
           amylase and digest starch and benefited from the human food they were
           scavenging. Domesticated dogs produce much more amylase compared to
           wolves and this allows dogs to benefit from a high-starch diet of humans in a
           way that wolves never could.

           3.1.1     Using the example given in the passage, describe how a population
                     of wolves may have evolved to form the first population of dogs.            (6)

           3.1.2     Although all dogs are descendants of the wolf, the use of artificial
                     selection has allowed humans to drastically alter the appearance of
                     dogs. For centuries, dogs have been bred for various desired
                     characteristics, leading to the creation of a wide range of dogs, from
                     the tiny Chihuahua to the massive Great Dane.

           (a)       Explain why all breeds of domestic dogs belong to the same species.         (3)

           (b)       Describe how artificial selection has led to the different breeds of
                     domestic dogs.                                                              (3)

                                                                                                 (12)

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 3.2       The diagram below represents the changes in a population of bacteria as
           a result of exposure to an antibiotic over time.

                          Diagram A                          Diagram B

                                                      Key

                                         Low                      High

                                            Antibiotic resistance level

             3.2.1 Explain, in terms of natural selection, the change in the proportion           (6)
                   of antibiotic resistant bacteria in the population in diagram B

             3.2.2 Explain why antibiotic resistance can become a severe health                   (3)
                   problem in hospitals

                                                                                                  (9)

   3.3        Read the following extract.

              Since 1972, biologists Peter and Rosemary Grant have studied finch
              populations in the Galapagos Islands. They studied one finch population on
              an island called Daphne Major.
              The table below shows the data they collected over a period of 7 years.

                  Year           1974       1975     1976     1977        1978   1979    1980
         Rainfall (mm)             -          -       130       20         130     70      50
         Number of finches       1 100      1 300    1 100     200         350    300     250
         Small seeds (mg/m2)       -         800      600       90         300     70      50

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           3.3.1       Use the information in the table to draw a line graph to show the       (6)
                       number of finches from 1974 until 1980.

           3.3.2       In which year were the largest drop in rainfall, number of seeds and    (1)
                       number of finches recorded?

           3.3.3       Explain how the three events mentioned in QUESTION 3.3.2 are            (4)
                       related to each other.

           3.3.4       When the number of finches decreased, there were still plenty of
                       large seeds on the island. What does this tell you about the seed-
                       eating habits of the finches that died?                                 (1)
                                                                                               (12)
 3.4      The diagram below shows some processes that occur during protein synthesis.

 3.4.1    Identify:

          (a) Molecule Y                                                                       (1)

          (b) Organelle V                                                                      (1)

          (c) Structure Z                                                                      (1)

 3.4.2    Give the sequence of nitrogenous bases for the first codon on Molecule Y
          (1, 2, 3).                                                                           (1)
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 3.4.3    Give the correct order in which molecules P, Q, R and S would attach to
          molecule Y. (From left to right)                                                  (2)

 3.4.4    Where in a cell does stage X occur?                                               (1)

 3.4.5    If the third nitrogenous base (A) of the DNA strand was replaced by G,
          describe how this would affect the protein that will form.                        (4)

 3.4.6    Describe the process of transcription                                             (6)
                                                                                            (17)

                                                                 TOTAL QUESTION 3:          50
                                                                     GRAND TOTAL:           150

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ERRATUM: LFSC PREP PAPER 2 MARKING GUIDELINE 2022

ENGLISH

1.2.7   Centromere 

1.2.8     Delete

 1.4    1.4.1      (a) Crossing over                                            (1)
                   (b) Prophase                                                 (1)

        1.4.2      Y - Chiasma                                                  (1)

        1.4.3      - Homologous chromosomes/bivalents pair up
                   - Each chromosome has 2 chromatids
                   - Chromatids overlap/cross over
                   - Genetic material is exchangedbetween non-sister
                     chromatids
                   - After the process of crossing-over chromosomes have genes
                     from the homologous partner
                                                                    Max          (3)

                                                                                 (6)

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                          NATIONAL
                   SENIOR CERTIFICATE

                          GRADE 12

                      LIFE SCIENCES P2
                      SEPTEMBER 2022
                   MARKING GUIDELINES

MARKS: 150

                This memorandum consists of 11 pages

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                                       MARKING GUIDELINE

 PRINCIPLES RELATED TO MARKING LIFE SCIENCES 2022

 1.         If more information than marks allocated is given
            Stop marking when maximum marks is reached and put a wavy line and 'max'
            in the right hand margin.

 2.         If, for example, three reasons are required and five are given
            Mark the first three irrespective of whether all or some are correct/ incorrect.

 3.         If whole process is given when only part of it is required
            Read all and credit relevant part.

 4.         If comparisons are asked for and descriptions are given
            Accept if differences/similarities are clear.

 5.         If tabulation is required but paragraphs are given
            Candidates will lose marks for not tabulating.

 6.         If diagrams are given with annotations when descriptions are required
            Candidates will lose marks.

 7.         If flow charts are given instead of descriptions
            Candidates will lose marks.

 8.         If sequence is muddled and links do not make sense
            Where sequence and links are correct, credit. Where sequence and links are
            incorrect, do not credit. If sequence and links becomes correct again, resume
            credit.

 9.         Non-recognized abbreviations
            Accept if first defined in answer. If not defined, do not credit the unrecognised
            abbreviation but credit the rest of answer if correct.

 10.        Wrong numbering
            If answer fits into the correct sequence of questions but the wrong
            number is given, it is acceptable.

 11.        If language used changes the intended meaning
            Do not accept.

 12.        Spelling errors
            If recognizable, accept, provided it does not mean something else in Life
            Sciences or if it is out of context.

 13.        If common names given in terminology
            Accept, provided it was accepted at the National memo discussion meeting.

 14.        If only letter is asked for and only name is given (and vice versa)
            No credit.

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                                        MARKING GUIDELINE

 15.        If units are not given in measurements
            Memorandum will allocate marks for units separately, except where it is already
            given in the question.

 16.        Be sensitive to the sense of an answer, which may be stated in a different
            way.

 17.        Caption
            Credit will be given for captions to all illustrations (diagrams, graphs, tables,
            etc.) except where it is already given in the question.

 18.        Code-switching of official languages (terms and concepts)
            A single word or two that appears in any official language other than the
            learners' assessment language used to the greatest extent in his/her answers
            should be credited, if it is correct. A marker that is proficient in the relevant
            official language should be consulted. This is applicable to all official languages.

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                                       MARKING GUIDELINE

 SECTION A
 QUESTION 1

 1.1        1.1.1       D
            1.1.2       B
            1.1.3       B
            1.1.4       C
            1.1.5       A
            1.1.6       C
            1.1.7       B
            1.1.8       C
            1.1.9       D
            1.1.10      B                                                      (10 x 2)   (20)

 1.2        1.2.1       Independentvariable
            1.2.2       (Law of) segregation
            1.2.3       Heterozygous
            1.2.4       Extinction
            1.2.5       Cytokinesis
            1.2.6       Foramen magnum
            1.2.7       Centromere
                                                                                            (7)

 1.3        1.3.1       A only
            1.3.2       A only
            1.3.3       Both A and B
                                                                                  (3 x 2)   (6)

 1.4        1.4.1       (a) Crossing over                                                  (1)
                        (b) Prophase                                                       (1)

            1.4.2       Y - Chiasma                                                        (1)

            1.4.3       - Homologous chromosomes/bivalents pair up
                        - Each chromosome has 2 chromatids
                        - Chromatids overlap/cross over
                        - Genetic material is exchangedbetween non-sister
                          chromatids
                        - After the process of crossing-over chromosomes have genes
                          from the homologous partner
                                                                         Max                (3)
                                                                                            (6)

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                                       MARKING GUIDELINE

 1.5        1.5.1       This is a Dihybrid cross:
                        It is a cross between two individuals
                        with two observed traits/ coat colour and horn length
                        that are controlled by two distinct genes.                        (2)

            1.5.2       BbHh                                                              (1)

            1.5.3       (a) BBHh                                                         (2)
                        (b) BBhh = black coat colour; short horns                        (2)

            1.5.4       BBHh = 4
                                     8 x Black coat; Long horns
                        BbHh = 4
                                                                   
                        Bbhh = 4
                                     8 x Black coat; Short horns
                        BBhh = 4

                        8 x 100     = 50 %
                        16                                                                 (3)

            1.5.5       (Principle of) Independent Assortment                              (1)
                                                                                           (11)

                                                                    TOTAL SECTION A:       50

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                                          MARKING GUIDELINE

 SECTION B

 QUESTION 2

 2.1
           2.1.1          (a) Cell membrane 
                          (b) Spindle fibres                                             (2)

           2.1.2          The chromosomes are of the:
                           - Same size
                           - Same shape
                           - Same length
                             Any                                                          (2)
                          (Mark first TWO only)

           2.1.3          1 - Metaphase 1
                          2 - Prophase 1
                          3 - Metaphase 2                                                  (3)

           2.1.4          - Crossing over                                                  (2)
                          - Random arrangement of chromosomes
                          (Mark first TWO only)                                           (9)

 2.2      P1/parent        phenotype         blue eyes x brown eyes
                           genotype              bb x      Bb 
          Meiosis
          G/gametes                          b, b   x B, b

          Fertilisation
          F1/offspring genotype              Bb, bb, Bb & bb 

                  phenotypes       2 blue eyes and 2 brown eyes
                    genotypes        Bb, bb, Bb, bb
          Parents and offspring/P1 and F1
          Meiosis and fertilisation                                         Any                (6)
                                     OR
          P1/parent    phenotype blue eyes x brown eyes
                       genotype              bb x Bb 

          Meiosis                      gametes      B       b
          Fertilisation                   b         Bb      bb
                                          b         Bb      bb
                                1 mark for correct gametes
                                1 mark for correct genotypes

          F1/offspring:   phenotype    2 blue eyes and 2 brown eyes
          Parents and offspring/P1 and F1
          Meiosis and fertilisation                                          Any               (6)

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                                      MARKING GUIDELINE

2.3
                2.3.1
                - Individual 5 is an affected male✓ and
                - He must have one Y chromosome✓ and
                - the recessive allele on the X chromosome✓
                - which he would have inherited from his mother (individual 2) ✓
                - But she does not have the disorder✓, which means it is caused by a
                   recessive allele                                                        (5)

                2.3.2 (a)       3:   XnXn✓

                        (b)     4:   XNY ✓                                                 (2)

                2.3.3 0% ✓                                                                 (1)
                                                                                           (8)
 2.4
          2.4.1      Planning:
                      • Get permission from all stakeholders/ the learners and
                         their parents 
                      • Decide on the sample size/ composition/ participants 
                      • Decide on the method to use to determine the blood
                         groups/ ensure that the learners know their blood
                         groups 
                      • Determine the apparatus and equipment needed to test for
                         the different blood groups 
                      • Design a record sheet 
                      • Set a date/ time for the investigation 
                      • Arrange venue 
                        (Mark first TWO only)                                Any
                                                                                           (2)

          2.4.2      B                                                                    (1)

          2.4.3      Represent separate/discrete/different
                     entities/blood groups /units
                                                   OR
                     Discontinuous variable / No  intermediate groups                  (2)

          2.4.4      45 %  /Majority of the sample group have blood group A
                                                    OR
                     10 %  /Minority of the sample group have blood group B
                                                    OR
                     20 % of the sample group have blood group AB
                                                    OR
                     35 % of the sample group have blood group O                         (2)
          2.4.5      The sample group was very small/ only one group of learners
                     from an entire school
                     and is therefore not representative of the world population          (2)
                                                                                           (9)

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                                       MARKING GUIDELINE

 2.5
          2.5.1      2 mya                                                                 (1)

          2.5.2      1450 cm3 – 430 cm3       (1450 – 430)  cm3
                     = 1020 cm3
                                                                                            (2)
          2.5.3      Have better co-ordination of movement
                     Process large amount of information
                     Processing information faster
                     Development of spoken and written              languages    to
                     communicate
                     (Mark first TWO only)                                                  (2)

          2.5.4      Table                                                                 (1)
                      Homo sapiens               African ape/Gorilla
                      Large cranium             Small cranium
                      Smaller jaw               Bigger jaw
                      Non-prognathous           Prognathous
                      Smaller teeth/canines     Bigger teeth/canines
                      Brow ridge reduced/       Brow ridge large/
                      absent                     pronounced
                      Well-developed chin       Less developed chin
                     (Mark first THREE only)                                                (6)
                                                                                            (7)
          2.5.5
                     •   The foramen magnum moved from a backwards
                         position to a more forward position in the modern human
                     •   The curvature of the spinechanged from C-shaped
                          to S-shaped
                     •   The pelvis changed from long and narrow to wider
                         and shorter. 
                         (Mark first TWO only)
                                                                                            (4)
                                                                                            (16)

 2.6      2.6.1      (a) new equipment is expensive
                         labour intensive
                         many clinical trialsmust be done/long time to produce a
                         safe product
                         (Mark first ONE only)                                   Any        (1)

                     (b) may easily pollinate non-GM crops/may mate with non-GM
                         animals
                         they might out-compete the naturally occurring organisms
                         (Mark first ONE only)                                  Any         (1)
                                                                                            (2)

                                                             TOTAL QUESTION 2:              [50]

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                                        MARKING GUIDELINE

QUESTION 3

  3.1
             3.1.1     •   there is variation in the wolves
                       •   in terms of their behaviour/ reduced aggression
                       •   and genetics / ability to produce amylase/ digest starch
                       •   A population of less aggressive/more tame wolves✓
                           were separated✓from the original wild population
                       •   They became scavengers✓ around human settlements
                           because they could digest the starch in human food ✓
                       •   and were more suited for survival ✓amongst a human
                           population
                       •   The genes for producing more amylase were passed on to
                           their offspring✓
                       •   The next generation had a higher proportion of individuals
                           with the favourable characteristic ✓
                                                                                   Max 6        (6)
             3.1.2     (a) They can interbreedwith different domestic dog breeds
                           to produce fertile offspring                                        (3)

                       (b) Humans chose desired characteristics✓
                           and bred dogs with those phenotypes and genotypes
                           to create dogs that suit their needs ✓/
                           e.g. hunters, companions, helpers.                                   (3)
                                                                                                (12)
  3.2
             3.2.1     -   Due to a mutation
                       -   some bacteria are resistant to the antibiotic and
                       -   others are not
                       -   There is a large degree of variation in the bacteria
                           population
                       -   When the antibiotic was first used,
                       -   the non-resistant bacteria died 
                       -   The resistant bacteria survived
                       -   to reproduce thereby
                       -   increasing the population of antibiotic-resistant bacteria
                                                                                      Any
                                                                                     Max 6      (6)

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                                                        MARKING GUIDELINE

           3.2.2     -   Overuse/ frequent use of antibiotics
                     -   may lead to the development of antibiotic resistant strains of
                         bacteria /Infections caused by these bacteria are no longer
                         affected by the antibiotic treatment
                     -   Antibiotic resistance leads to higher medical costs, prolonged
                         hospital stays, and increased mortality. 
                                                                                                                        (3)
                                                                                                                        (9)

3.3
           3.3.1
                                                        Number of finches from 1974 to 1980

                                    Number of finches
                                                         1400
                                                         1200
                                                         1000
                                                          800
                                                          600
                                                          400
                                                          200
                                                            0

                                                                 1974   1975   1976   1977    1978      1979   1980

                                                                               Time (years)

                       Rubric for awarding marks for the graph
                       Correct type of graph                                 1
                       Title of graph                                        1
                       Correct label for X and Y-axes                        1
                       Correct scale and units for X and                     1
                       Y-axes
                       Plotting points                       1:     1 - 4 correctly plotted
                                                             2:     All 7 correctly plotted
                     NOTE:
                     If the wrong type of graph is drawn: marks will be forfeited for
                     "correct type of graph" as well as for the ''joining of points''.
                                                                                                                              (6)
           3.3.2     1977
                                                                                                                              (1)
           3.3.3     A drop in rainfall/ drought
                     causes a drop in seed production/plant growth
                     causing less food to support fewer finches
                                                                                                                              (4)
           3.3.4     the beaks of these finches were too small/ not strong enough to be
                     able to eat the large seeds
                                                                                                                              (1)
                                                                                                                              (12)

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                                     MARKING GUIDELINE

3.4
           3.4.1     (a) Molecule Y: mRNA
                     (b) Organelle V: ribosome
                     (c) Structure Z: nuclear membrane                                     (3)

           3.4.2     First codon on molecule Y: AGU                                        (1)

           3.4.3     R; S; P; Q (must be in correct order)                                (2)

           3.4.4     Cytoplasm                                                             (1)

           3.4.5     If nitrogenous base A is replaced by G, the codon will change to
                     AGC 
                     This will code for another anticodon/ UCA instead of AGU
                     And may result in coding for another amino acid
                     which may change the protein that is formed                           (4)

           3.4.6     The double helix DNA unwinds
                     The double-stranded DNA unzips/ weak hydrogen bonds break
                     to form two separate strands
                     One strand is used as a template
                     to form mRNA
                     using free RNA nucleotides from the nucleoplasm. 
                     The mRNA is complementary to the DNA. 
                     mRNA now has the coded message for protein synthesis  (Any 6)         (6)
                                                                                            (17)

                                                                   TOTAL QUESTION 3:        50

                                                                        GRAND TOTAL:        150

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