# Life Sciences Grade 12 Paper 2 Mpumalanga Mock 2022 Memo

> Grade 12 Life Sciences Paper 2 memorandum from the Mpumalanga Mock Exam 2022, 30 pages. Read online or download the free PDF.

- Page: https://www.hlayiso.com/library/mp-life-sciences-grade-12-sept-2022-p2-and-memo/d062247a-65ab-4c50-872c-c5027242cb3d
- Updated: 2026-09-27
- Subject: Life Sciences
- Grade: Grade 12
- Document type: Memorandum
- Year: 2022
- Exam period: Mpumalanga Mock Exam
- Paper: 2
- Curriculum: CAPS
- Pages: 30

Breadcrumbs: [Home](https://www.hlayiso.com/) › [Library](https://www.hlayiso.com/library) › [Grade 12](https://www.hlayiso.com/library/grade-12) › [Life Sciences](https://www.hlayiso.com/library/grade-12/life-sciences) › [Life Sciences Grade 12 Paper 2 Mpumalanga Mock 2022 Memo](https://www.hlayiso.com/library/mp-life-sciences-grade-12-sept-2022-p2-and-memo/d062247a-65ab-4c50-872c-c5027242cb3d)

## About this document

Life Sciences · Grade 12 · Mpumalanga Mock Exam · 2022. Memorandum, 30 pages. Read online or download the PDF.

Read it free online on the page above; download the PDF from there.

## Document text

Text extracted from the PDF. Layout, diagrams and tables may not survive extraction.

### Page 1

Downloaded from hlayiso.com
    Downloaded f rom St anmorephysics. com
.

                      PREPARATORY EXAMINATION

                                    GRADE 12

                               LIFE SCIENCES P2

                               SEPTEMBER 2022

MARKS: 150
TIME: 2½ HOURS

                       This question paper consists of 16 pages

Copyright reserved                                                Please turn over

### Page 2

Downloaded from hlayiso.com
        Downloaded f rom St anmorephysics.
       Life Sciences/P2           2        com                               MDE/September 2022

 INSTRUCTIONS AND INFORMATION

 Read the following instructions carefully before answering the questions.

 1.          Answer ALL the questions.

 2.          Write ALL the answers in your ANSWER BOOK.

 3.          Start the answers to each question at the top of a NEW page.

 4.          Number the answers correctly according to the numbering system used in this
             question paper.

 5.
                                                                          s.co
             Present your answers according to the instructions of each question.

 6.
                                                                              m
             ALL drawings should be done in pencil and labelled in blue or black ink.
                                                                     si c
 7.          Draw diagrams or flow charts only when asked to do so.
                                              st
 8.                                              an
             The diagrams in this question paper are NOT necessarily drawn to scale.

 9.          Do NOT use graph paper.
                                                   mor
 10.                                                   ep
             You may use a non-programmable calculator, protractor and a compass.
                                                         hy
 11.         Write neatly and legibly.
                                          om
                                         fr
                           oa
                             de
                               d
                do
                  wn
                    l

Copyright reserved                                                              Please turn over

### Page 3

Downloaded from hlayiso.com
        Downloaded f rom St anmorephysics.
       Life Sciences/P2           3        com                                   MDE/September 2022

 SECTION A

 QUESTION 1

 1.1       Various options are provided as possible answers to the following questions.
           Choose the answer and write only the letter (A to D) next to the question number
           (1.1.1 to 1.1.10) in your ANSWER BOOK, for example 1.1.11 D.

           1.1.1     The process where one DNA molecule produces two identical DNA
                     molecules is called …

                      A     reproduction.
                      B     replication.
                      C
                      D
                            translation.
                            transcription.
                                                                             s.co
           1.1.2                                                                 m
                     If half of a population mates in January and the other half mates in June,
                     they will eventually become different species.     si c
                                                 st
                     Which ONE of the following correctly describes the reproductive
                                                    an
                     isolation mechanism given above?

                      A                               mor
                            Different courtship patterns
                      B     Species-specific courtship behaviour
                      C     Prevention of fertilisation   ep
                      D                                     hy
                            Breeding at different times of the year

           1.1.3     When a DNA template strand that contains 22% adenine bases is
                                             om
                     transcribed, the mRNA produced will have …

                      A
                                       fr
                            22% thymine bases.
                      B     22% cytosine bases.
                      C     oa
                            22% uracil bases.
                      D       de
                            22% guanine bases.

           1.1.4
                                d
                      In an investigation, a chemical was used to prevent spindle fibres from
                do    forming in cells. This chemical was added to cells in the anthers of the
                  wn  flowers of rice plants. Each cell in the anther has 24 chromosomes.
                    l
                      What is the expected number of chromosomes in each daughter cell
                      at the end of meiosis?

                       A    12 replicated chromosomes
                       B    24 replicated chromosomes
                       C    24 unreplicated chromosomes
                       D    48 unreplicated chromosomes

Copyright reserved                                                                  Please turn over

### Page 4

Downloaded from hlayiso.com
        Downloaded f rom St anmorephysics.
      Life Sciences/P2            4        com                              MDE/September 2022

            1.1.5    The diagram below represents one pair of homologous chromosomes
                     during crossing over.

                           P                  Q      R                  S

                     The allele sequence for chromatid S after the completion of crossing
                     over will be…

                     A    A, B, c
                     B    A, b, C
                     C    a, b, c
                     D    a, b, C

            1.1.6    The diagram below shows the pattern of inheritance of a disorder.

                     One can conclude that the disorder is caused by a …

                     A    recessive allele, with both parents homozygous recessive.
                     B    recessive allele, with both parents heterozygous.
                     C    dominant allele, with one parent heterozygous while the other is
                          homozygous dominant.
                     D    dominant allele, with both parents homozygous recessive.

Copyright reserved                                                             Please turn over

### Page 5

Downloaded from hlayiso.com
        Downloaded f rom St anmorephysics.
      Life Sciences/P2            5        com                                  MDE/September 2022

            1.1.7    A scientist wanted to determine the variation in neck length of adult
                     male ostriches.

                     Which ONE of the following steps was done to ensure the validity of
                     the investigation?

                     A        Permission was obtained to conduct the investigation
                     B        A random sample of adult male ostriches was selected
                     C        He measured the neck lengths of 65 adult male ostriches
                     D        The average neck length of the 65 ostriches were calculated

            1.1.8    Which of the following indicates that Darwin’s and Lamarck’s theories
                     are similar?

                         A    Acquired characteristics of organisms are passed from parents to
                              offspring.
                     B        Population as a whole changes.
                     C        Evolution depends on changes in the environment.
                     D        Evolution happens very rapidly

            1.1.9    Some genes from the bacterium E. coli have sequences that are similar
                     to genes found in humans.

                     This statement is an example of which type of evidence?

                     A        Biogeography
                     B        Fossil
                     C        Genetic
                     D        Modification by descent

            1.1.10   The table below compares the rate of extinction of mammal species
                     over two different time periods.

                                 TIME PERIOD                RATE OF EXTINCTION
                                    (YEARS                    (PER 100 YEARS)
                                   1500–1900                        4,5
                                  1900–2000                            90

                     What is the ratio between the rate of extinction from 1500 to 1900
                     compared to the rate of extinction from 1900 to 2000?

                     A        1: 20
                     B        1: 2
                     C        2: 1
                     D        20: 1                                                   (10 x 2)        (20)

Copyright reserved                                                                 Please turn over

### Page 6

Downloaded from hlayiso.com
        Downloaded f rom St anmorephysics.
       Life Sciences/P2           6        com                               MDE/September 2022

 1.2         Give the correct biological term for each of the following descriptions. Write
             only the term next to the question number (1.2.1 to 1.2.10) in your ANSWER
             BOOK.

             1.2.1    The monomers of DNA

             1.2.2    The bond formed between two monomers of a protein

             1.2.3    Structures formed when the centrosome divides into two

             1.2.4    Chromosomes involved in sex determination

             1.2.5    An arrangement of black bars representing DNA fragments that can be
                      used to determine whether people are related

             1.2.6    The number, size and shape of chromosomes in a body cell

             1.2.7    The period between two consecutive cell divisions

             1.2.8    The family to which humans belong

             1.2.9    Specific parts of DNA that carry the codes for characteristics of
                      organisms

             1.2.10 The different characteristics that occur naturally from one individual to
                    another in a population                                          (10 x 1)      (10)

 1.3        Indicate whether each of the statements in COLUMN I apply to A ONLY, B
            ONLY, BOTH A AND B or NONE of the items in COLUMN II. Write A only, B
            only, both A and B or none next to the question number (1.3.1 to 1.3.4) in the
            ANSWER BOOK.

                            COLUMN I                             COLUMN II
             1.3.1    The significance of RNA          A:    Replicates DNA
                                                       B:    Reduces the number of
                                                             chromosomes
             1.3.2    The site of protein synthesis    A:    Mitochondrion
                                                       B:    Ribosomes
             1.3.3    The pairing of chromosomes       A:    Mutation
                                                       B:    Non-disjunction
             1.3.4    Capable of bipedal locomotion    A:    Homo erectus
                                                       B:    Australopithecus africanus

                                                                                     (4 x 2)       (8)

Copyright reserved                                                              Please turn over

### Page 7

Downloaded from hlayiso.com
        Downloaded f rom St anmorephysics.
       Life Sciences/P2           7        com                                         MDE/September 2022

 1.4         The diagram below shows the dentition of three genera.

                                     A                      B                          C

             1.4.1    Give only the LETTER(S) (A, B or C) of the organisms that is/are:

                          (a)   Most likely to eat raw food only.                                             (2)

                          (b)   Most likely to eat soft, cooked food.                                         (1)

             1.4.2    Which diagram (A, B or                C)      represents   the   dentition      of
                      Australopithecus afarensis?                                                             (1)

             1.4.3    Give ONE observable reason for your answer to QUESTION 1.4.2                            (1)

             1.4.4    Give the correct sequence of the organisms (A, B and C) from most
                      primitive to most evolved.                                                              (2)
                                                                                                              (7)

Copyright reserved                                                                         Please turn over

### Page 8

Downloaded from hlayiso.com
        Downloaded f rom St anmorephysics.
       Life Sciences/P2           8        com                                  MDE/September 2022

 1.5     The diagram below shows a genetic engineering process. A donor cell was taken
         from the skin cell of a male pig to create a new offspring.

                                                        A
                                                                            C

                                                                                   D

         1.5.1       Name the genetic engineering process shown in the diagram above.                (1)

         1.5.2       Name the type of cell division through which:

                     (a)    Cell D divides.                                                          (1)

                     (b)    Ovum B is produced.                                                      (1)

         1.5.3       A somatic cell in a pig contains 38 chromosomes.

                     How many chromosomes would there be in:

                     (a)    Structure A                                                              (1)

                     (B)    A skin cell in organism E                                                (1)
                                                                                                     (5)

                                                                        TOTAL SECTION A:             50

Copyright reserved                                                                Please turn over

### Page 9

Downloaded from hlayiso.com
        Downloaded f rom St anmorephysics.
       Life Sciences/P2           9        com                                      MDE/September 2022

 SECTION B

 QUESTION 2

 2.1        The diagram below represents a stage of protein synthesis.

                                                                                            R
                                                          Q

                                                                                             S
                                 P

                                                      AUG CAU CUA
                                                                                           W

            2.1.1    Identify molecule:

                     (a)    P                                                                            (1)

                     (b)    S                                                                            (1)

            2.1.2    If R is the next amino acid required after Q, then identify:

                      (a)   Anticodon T                                                                  (2)

                      (b)   The DNA base triplet that codes for R.                                       (2)

            2.1.3    Describe the role of DNA during the formation of molecule W.                        (2)

            2.1.4    Name and describe the process represented in the diagram.                            (7)
                                                                                                         (15)

Copyright reserved                                                                    Please turn over

### Page 10

Downloaded from hlayiso.com
         Downloaded f rom St anmorephysics.
       Life Sciences/P2            10       com                                MDE/September 2022

 2.2         The diagram below represents a phase of meiosis in animals.

                                                      V

                                                                         W

                                                                         X

             2.2.1    Identify the phase represented by the diagram.                                (1)

             2.2.2    Give ONE visible reason for your answer to QUESTION 2.2.1.                    (1)

             2.2.3    Label part W.                                                                 (1)

             2.2.4    State ONE function of part X.                                                 (1)

             2.2.5    Name the female organ where meiosis occurs.                                   (1)

             2.2.6    Give the number of chromosomes in each cell at the end of meiosis
                      represented by this diagram.                                                  (1)

             2.2.7    List THREE characteristics that the two structures indicated by V have
                      in common.                                                                    (3)

             2.2.8    Explain TWO ways in which meiosis is important.                                (4)
                                                                                                    (13)

Copyright reserved                                                               Please turn over

### Page 11

Downloaded from hlayiso.com
         Downloaded f rom St anmorephysics.
       Life Sciences/P2            11       com                                 MDE/September 2022

 2.3       Human eyebrows are either connected or not connected to each other.

                  Eyebrows not connected                     Eyebrows connected

          The pedigree diagram below shows the inheritance of ‘connected’ and ‘not
          connected’ eyebrows in a family.

                                         A            B

                                              E      F
              Key:

                     Male with eyebrows                  Female with eyebrows
                     not connected                       not connected
                     Male with eyebrows                  Female with eyebrows
                     connected                           connected

                  Pedigree diagram showing inheritance of connected and not
                                   connected eyebrows

          2.3.1      Which type of eyebrows is controlled by the dominant allele?                      (1)

          2.3.2      Give a reason for your answer to QUESTION 2.3.1 using evidence from
                     the pedigree diagram.                                                             (2)

Copyright reserved                                                                  Please turn over

### Page 12

Downloaded from hlayiso.com
         Downloaded f rom St anmorephysics.
       Life Sciences/P2            12       com                                     MDE/September 2022

          2.3.3      State the number of:

                     (a)    Generations represented in this pedigree diagram                             (1)

                     (b)    Offspring of individuals C and D                                             (1)

          2.3.4      What percentage of the females in this family has connected eyebrows?
                     Show ALL workings.                                                                  (2)

          2.3.5      State Mendel’s law of dominance.                                                    (2)
                                                                                                         (9)

 2.4      Blood groups are an inherited characteristic. The table below shows the
          percentage people in a community with each of the different blood groups.

                            Blood group                  O        A         B        AB
                            Percentage of the
                                                         46       35       14         5
                            community (%)

          2.4.1       How many genes control blood groups?                                               (1)

          2.4.2       (a)    What is the blood group of an individual with the genotype IA IB?           (1)

                      (b)    How does the inheritance of the blood group mentioned in
                             QUESTION 2.4.2(a) differ from the inheritance of other blood
                             groups?                                                                     (1)

          2.4.3       Give the possible genotypes for blood group A.                                     (2)

          2.4.4       Explain how it is genetically possible to have four blood groups in a
                      community.                                                                         (2)

          2.4.5       Draw a bar graph to represent the information in the table.                         (6)
                                                                                                         (13)

                                                                                                         [50]

Copyright reserved                                                                    Please turn over

### Page 13

Downloaded from hlayiso.com
         Downloaded f rom St anmorephysics.
       Life Sciences/P2            13       com                                    MDE/September 2022

 QUESTION 3

 3.1      A group of learners investigated the frequency of dominant and recessive
          genetic traits in their school. Their hypothesis was:

          There are more learners with dominant genetic traits than learners with
          recessive genetic traits.

          They investigated 200 learners for the following traits:

                     DOMINANT TRAIT                      RECESSIVE TRAIT
                     Unattached earlobe                  Attached earlobe
                     Rolled tongue                       Unrolled tongue
                     Bent little finger                  Straight little finger

          The table below shows the results obtained.

                                                      NUMBER OF LEARNERS
                              TRAIT                DOMINANT        RECESSIVE
                     Earlobe                          70              130
                     Tongue                           24              176
                     Little finger                    15              185

          3.1.1      Identify the independent variable for this investigation.                          (1)

          3.1.2      Explain why the age of the learners need NOT be controlled in this
                     investigation.                                                                     (2)

          3.1.3      State ONE way in which the learners can increase the reliability of their
                     results.                                                                           (1)

          3.1.4      List ONE planning step the learners had to follow before starting to collect
                     the data.                                                                          (1)

          3.1.5      Will the learners accept or reject their hypothesis?                               (1)

          3.1.6      Explain your answer to QUESTION 3.1.5.                                             (2)
                                                                                                        (8)

Copyright reserved                                                                   Please turn over

### Page 14

Downloaded from hlayiso.com
         Downloaded f rom St anmorephysics.
       Life Sciences/P2            14       com                                    MDE/September 2022

 3.2      Haemophilia is a sex-linked disorder that causes excessive bleeding due to a
          lack of the blood clotting protein. This disorder is caused by a recessive allele
          on the X-chromosome (Xh)

          3.2.1      Explain why this disorder affects mostly males in a family.                        (3)

          3.2.2      A man with haemophilia and a woman who is heterozygous for
                     haemophilia, decide to have children.

                     Use a genetic cross to show all the possible genotypes of their children.          (6)
                                                                                                        (9)

 3.3      Scientists carried out an investigation to determine the development of insecticide
          resistance of insects. A population of insects was treated with an insecticide from
          the year 1995 to 1998. The percentage that was resistant to the insecticide was
          calculated.

          The table below shows data from an insect population in 1995 and 1998.

                      CHANGE IN THE RESISTANCE TO INSECTICIDE IN AN INSECT
                                          POPULATION
                      Characteristic   Percentage of       Percentage of
                                     population in 1995 population in 1998
                       Resistance          0,15                99,1

          3.3.1      Describe the change in the insecticide resistance of the insect population
                     between 1995 and 1998.                                                             (2)

          3.3.2      Describe how natural selection caused insecticide resistance in this
                     population.                                                                        (7)
                                                                                                        (9)

Copyright reserved                                                                   Please turn over

### Page 15

Downloaded from hlayiso.com
         Downloaded f rom St anmorephysics.
       Life Sciences/P2            15       com                                 MDE/September 2022

 3.4      The diagram below shows an evolutionary process taking place in a population of
          salamanders. The process took place gradually, millions of years ago. Study the
          diagram and answer the questions that follow.

          3.4.1      Which evolutionary process is shown in the diagram?                                (1)

          3.4.2      Use the diagram to explain how species B evolved from the original
                     species.                                                                           (6)

          3.4.3      Explain why this is not an example of punctuated equilibrium.                       (4)
                                                                                                        (11)

Copyright reserved                                                                   Please turn over

### Page 16

Downloaded from hlayiso.com
         Downloaded f rom St anmorephysics.
       Life Sciences/P2            16       com                                 MDE/September 2022

 3.5         The diagrams below show the skeletons of a gorilla and a human.

                                 Gorilla                          Human

             3.5.1    State THREE characteristics of the upper limbs that are the same in
                      both species.                                                                  (3)

             3.5.2    Name TWO Australopithecus fossils that were found in South Africa.             (2)

             3.5.3    Explain the significance of the change of the pelvis towards bipedalism.       (4)

             3.5.4    Explain how genetic evidence supports the hypothesis that all living
                      humans are “Out of Africa”.                                                     (4)
                                                                                                     (13)

                                                                                                     [50]

                                                                        TOTAL SECTION B:             100
                                                                           GRAND TOTAL:              150

Copyright reserved                                                                Please turn over

### Page 17

Downloaded from hlayiso.com
        Downloaded f rom St anmorephysics. com

                                     GRADE 12

                               LIFE SCIENCES P2

                                SEPTEMBER 2022

                             MARKING GUIDELINES

       MARKS: 150

                      These marking guidelines consist of 13 pages.

Copyright reserved                                                    Please turn over

### Page 18

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            2       com                                   MDE/September 2022
                                            Marking Guidelines

 PRINCIPLES RELATED TO MARKING LIFE SCIENCES

 1.    If more information than marks allocated is given
       Stop marking when maximum marks is reached and put a wavy line and ‘max’
       in the right-hand margin.

 2.    If, for example, three reasons are required and five are given
       Mark the first three irrespective of whether all or some are correct/incorrect.

 3.    If whole process is given when only a part of it is required
       Read all and credit relevant part.

 4.    If comparisons are asked for and descriptions are given
       Accept if differences / similarities are clear.

 5.    If tabulation is required but paragraphs are given
       Candidates will lose marks for not tabulating.

 6.    If diagrams are given with annotation when descriptions are required
       Candidates will lose marks.

 7.    If flow charts are given instead of descriptions
       Candidates will lose marks.

 8.    If sequence is muddled and links do not make sense
       Where sequence and links are correct, credit. Where sequence and links are
       incorrect, do not credit. If sequence and links become correct again, resume
       credit.

 9.    Non-recognised abbreviations
       Accept if first defined in answer. If not defined, do not credit the unrecognised abbreviation
       but credit the rest of answer if correct.

 10. Wrong numbering
     If answer fits into the correct sequence of questions but the wrong number is
     given it is acceptable.

 11. If language used changes the intended meaning
     Do not accept.

 12. Spelling errors
     If recognisable accept the answer provided it does not mean something else in Life
     Sciences or if it is out of context.

Copyright reserved                                                               Please turn over

### Page 19

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            3       com                                  MDE/September 2022
                                          Marking Guidelines

 13. If common names are given in terminology
     Accept provided it is accepted at the provincial memo discussion meeting

 14. If only letter is asked for and only name is given (and vice versa)
     Do not credit.

 15. If units are not given in measurements
     Candidates will lose marks. Memorandum will allocate marks for units separately

 16. Be sensitive to the sense of an answer, which may be stated in a different way.

 17. Caption
     All illustrations (diagrams, graphs, tables, etc.) must have a caption.

 18. Code-switching of official languages (terms and concepts)
     A single word or two that appears in any official language other than the learners’
     assessment language used to the greatest extent in his/her answers should be credited, if it
     is correct. A marker that is proficient in the relevant official language should be consulted.
     This is applicable to all official languages.

 19. Changes on the marking guideline
     No changes must be made to the marking guidelines without consulting the Provincial
     Internal Moderator.

Copyright reserved                                                              Please turn over

### Page 20

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            4       com                     MDE/September 2022
                                           Marking Guidelines

 SECTION A

 QUESTION 1

 1.1 1.1.1           B
     1.1.2           D
     1.1.3           C
     1.1.4           B
     1.1.5           D
     1.1.6           B
     1.1.7           B
     1.1.8           C
     1.1.9           C
     1.1.10          A                                                (10 x 2)       (20)

 1.2 1.2.1           Nucleotides
     1.2.2           Peptidebond
     1.2.3           Centrioles
     1.2.4           Gonosomes
     1.2.5           DNA profile
     1.2.6           Karyotype
     1.2.7           Interphase
     1.2.8           Hominidae
     1.2.9           Genes
     1.2.10          Variation                                         (10 x 1)       (10)

 1.3 1.3.1           None                                                            (2)

       1.3.2         B only                                                          (2)

       1.3.3         None                                                            (2)

       1.3.4         Both A and B                                                    (2)
                                                                          (4 x 2)      (8)

 1.4 1.4.1           (a) - A and C                                                   (2)
                     (b) - B                                                          (1)

       1.4.2         A                                                                (1)

       1.4.3         - Small gaps between the teeth/diastema
                     - U-shaped palate
                         (Mark first ONE only)                  Any 1                  (1)

       1.4.4         C  A B                                                        (2)
                                                                                       (7)

Copyright reserved                                                 Please turn over

### Page 21

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            5       com                   MDE/September 2022
                                      Marking Guidelines

 1.5 1.5.1           Cloning                                                        (1)

       1.5.2         (a) - Mitosis                                                  (1)
                     (b) - Meiosis                                                  (1)

       1.5.3         (a) - 38                                                       (1)
                     (b) - 38                                                       (1)
                                                                                     (5)

                                                           TOTAL SECTION A:          50

Copyright reserved                                               Please turn over

### Page 22

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            6       com                                MDE/September 2022
                                            Marking Guidelines

 SECTION B

 QUESTION 2

 2.1 2.1.1           (a) - Amino acid                                                            (1)
                     (b) - tRNA                                                                  (1)

       2.1.2         (a) - GUA                                                                  (2)
                     (b) - GTA                                                                  (2)

       2.1.3         - DNA provides the code for a particular protein
                     - One strand is used as a template to form the molecule W/mRNA              (2)

       2.1.4         Translation*
                     - Each t-RNA carries a specific amino acid
                     - according to its anticodon
                     - The anticodon attaches to the complementary codon
                     - on mRNA
                     - Then t-RNA brings the required amino acid to the ribosome
                     - arranging the amino acids in a specific sequence.
                     - Amino acids become attached by peptide bonds
                     - to form the required protein.
                                                                     1 Compulsory* + any 6        (7)
                                                                                                 (15)

Copyright reserved                                                            Please turn over

### Page 23

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            7       com                               MDE/September 2022
                                             Marking Guidelines

       2.2.1         Metaphase ‫׀‬                                                                  (1)

       2.2.2         - Chromosomes align in pairs at the equator/ homologous
                       chromosomes align in pairs at the equator of the cell                       (1)

       2.2.3         Cell membrane                                                                (1)

       2.2.4         - Forms spindle fibres
                     - Attaches spindle fibres to centromere                                      (1)

       2.2.5         Ovary/ovule                                                                  (1)

       2.2.6         (a) 3                                                                        (1)

       2.2.7         - Same size/length/height
                     - Same shape
                     - Same position of centromeres
                     - Same position of genes/alleles
                     - Genes coding for the same characteristics
                     (Mark first THREE only)                                           Any 3       (3)

       2.2.8         - Exchange of genetic material
                     - introduces variation

                     - Random arrangement of chromosomes
                     - to cause genetic variation

                     - Reduction of chromosome number to haploid
                     - to keep the chromosome number constant from generation to
                       generation

                     - Forms four haploid cells
                     - which function as gametes
                     (Mark first TWO only)                                       (Any 2 x 2)        (4)
                                                                                                   (13)

Copyright reserved                                                              Please turn over

### Page 24

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            8       com                                      MDE/September 2022
                                                  Marking Guidelines

 2.3 2.3.1           Eyebrows not connected                                                            (1)

       2.3.2         -         Parents A and B or C and D produce children with connected
                               eyebrows
                     -         and not connected eyebrows
                     -         Only parents both carrying the dominant allele can
                     -         produce offspring with both phenotypes

                                                      OR
                     -         A and B or C and D have eyebrows that are not connected,
                               produce a child with eyebrows which are connected
                     -         then the allele for connected eyebrows was present in both
                               parents,
                     -         but masked, so eyebrows that are connected is recessive.
                                                                                            Any 2       (2)

       2.3.3         (a) 4/FOUR                                                                        (1)

                     (b) 4/FOUR                                                                        (1)

       2.3.4         [4/7 x 100] = 57,14%                                                             (2)

       2.3.6         In a heterozygous condition the dominant allele expresses itself in the
                     phenotype, masking the effect of the recessive allele
                                                         OR
                     When two individuals with pure breeding contrasting characteristics are
                     crossed the offspring will display the dominant characteristic                   (2)
                                                                                                        (9)

 2.4   2.4.1         One gene                                                                          (1)

       2.4.2             (a)    AB                                                                     (1)

                         (b)    - In the other blood groups, the phenotypes show only one of the
                                  genes in the genotype, because the one dominates the other.
                                                                  OR
                                - In this blood group the alleles are co-dominant                      (1)

       2.4.3         IAIA
                     IAi                                                                               (2)

       2.4.4         Blood groups are controlled by three alleles IA, IB and i which, when in
                     combination, provide four phenotypes (A, AB, B, O).                               (2)

Copyright reserved                                                                  Please turn over

### Page 25

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            9       com                                        MDE/September 2022
                                               Marking Guidelines

       2.4.5

                               Criteria                    Mark Allocation              Mark
                     Correct type of graph (T)      Bar graph drawn                      1
                     Caption for graph (C)          Both variables included              1
                     Axes labels (L)                X- and Y-axis correctly              1
                                                    labelled with units
                     Scale for X-and Y-axis(S)      -Equal space between bars
                                                    and width of bars for X-axis          1
                                                    and
                                                    -Correct scale for Y-axis
                     Plotting of bars (P)           -1 to 3 bars plotted correctly
                                                                                           1
                                                    -All 4 bars plotted correctly          2
                                                                                                         (6)
                                                        NOTE:
                     - If the wrong type of graph is drawn:
                       Marks will be lost for ‘correct type of graph’
                     - and if a line graph is drawn marks for plotting of bars will be lost
                     - If axes are transposed: marks will be lost for labelling
                       and scaling of X-axis and Y axis
                                                                                                         (13)
                                                                                                         [50]

Copyright reserved                                                                    Please turn over

### Page 26

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            10      com                                   MDE/September 2022
                                              Marking Guidelines

 QUESTION 3

 3.1 3.1.1           Genetic traits                                                                (1)

       3.1.2         These traits are inherited   and not influenced by age                        (2)

       3.1.3         - Increase the number of learners
                     - Repeat the investigation
                      (Mark first ONE only)                                                        (1)

       3.1.4         - Get permission from school and parents to do the investigation
                     - Decide on venue where data will be collected
                     - Day/time when data will be collected
                     - Make sure that a random distribution of boys and girls are monitored
                     - Plan how the data will be collected and recorded
                     (Mark first ONE only)                                             Any 1       (1)

       3.1.5         Reject                                                                        (1)

       3.1.6         More learners displayed the recessive traits compared to the dominant
                     traits                                                                        (2)
                                                                                                   (8)

Copyright reserved                                                              Please turn over

### Page 27

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            11      com                                       MDE/September 2022
                                              Marking Guidelines

 3.2 3.2.1           - The allele for the trait is carried on the X-chromosome
                     - Males only have one X-chromosome
                     - A male therefore only needs one recessive alleleto have haemophilia
                     - A female must have two recessive alleles to have haemophilia                   (3)

 3.2 3.2.2           P1 Phenotype Man with haemophilia              x   Heterozygous women
                         Genotype   XhY                            x             XHXh

                     Meiosis
                           G/Gametes     Xh , Y         x         XH , Xh

                     Fertilisation
                     F1     Genotype        XH Xh, Xh Xh, XHY, Xh Y *
                             Phenotype 25% boys without haemophilia: 25% boys with
                                         haemophilia
                                         25% girls with haemophilia: 25% girls which are
                                         carriers
                     P1 and F1
                     Meiosis and fertilisation                       *1 compulsory + Any 5

                                                         OR

                     P1    Phenotype     Haemophilia          x          Carrier
                           Genotype      XhY                  x          XHXh

                                              Gametes      Xh       Y
                     Meiosis                  XH             H
                                                           X X  h   XHY
                                              Xh             h
                                                           X X  h   Xh Y
                     Fertilisation
                                              1 mark for correct gametes
                                              1 mark for correct genotypes*
                     F1    Genotype    XH Xh, Xh Xh, XHY, Xh Y *
                           Phenotype 25% boys without haemophilia: 25% boys with
                                     haemophilia                                                        (6)
                                     25% girls with haemophilia: 25% girls which are
                                     carriers

                     P1 and F1
                     Meiosis and fertilisation                         *1 compulsory + Any 5
                                                                                                        (9)

Copyright reserved                                                                  Please turn over

### Page 28

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            12      com                                      MDE/September 2022
                                             Marking Guidelines

 3.3 3.3.1           - There was an increase in the percentage of resistant insects
                       from 0,15% (in 1995) to 99,10% (in 1998)                                      (2)

       3.3.2         - There is variation in the insect population
                     - Some were resistant and some were not
                     - When the insecticide was first used, it killed off a large number of
                       non-resistant insects
                     - Some insects were resistant to the insecticide and survived
                     - Those that survived were able to reproduce
                     - Thereby passing on the allele (gene) for resistance to offspring
                     - Continued use of the insecticide had little effect on the resistant
                       insects
                     - Therefor the resistant insects increased and the
                     - non-resistant insects decreased                                    Any 7       (7)
                                                                                                       (9)

Copyright reserved                                                                 Please turn over

### Page 29

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            13      com                                  MDE/September 2022
                                             Marking Guidelines

 3.4 3.4.1           Speciation                                                                  (1)

       3.4.2         - The original population of salamander became separatedinto two
                     - by the central valley*/geographical barrier (Compulsory)
                     - No gene flow occurred between the populations
                     - Each population was exposed to different environmental
                     - conditions/selection pressure
                     - Natural selection occurred independently in each population
                     - The individuals in each population became different
                     - genotypically and phenotypically from each other
                     - Even if the two populations were to mix
                     - they would be unable to interbreed/ reproduce
                     - resulting in the formation of species B.
                                                                     1 compulsory* + Any 5        (6)

       3.4.3         In punctuated equilibrium:

                     - Evolution will involve long periods of time  where species do
                       not change /very little change occurs
                     - and this will alternate with short periods of time where rapid
                       changesoccur
                     - New species are formed in a short period of time
                     - supported by the absence of transitional fossils              Any 4       (4)

                                                                                                  (11)

Copyright reserved                                                             Please turn over

### Page 30

Downloaded from hlayiso.com
       Downloaded f rom St anmorephysics.
Life Sciences/Grade 12            14      com                                   MDE/September 2022
                                              Marking Guidelines

 3.5 3.5.1           - Freely rotating arms 
                     - Long upper arms
                     - Elbow joints which allow rotation of forearms
                     - Rotating hands
                     - Flat nails instead of claws
                     - Opposable thumbs
                     (Mark first THREE only)                                           Any 3       (3)

       3.5.2         - Little Foot
                     - Taung child / Australopithecus africanus
                     - Mrs Ples/ Australopithecus africanus
                     - Karabo / Australopithecus sediba
                     (Mark first TWO only)                                             Any 2       (2)

       3.5.3         - It became wide and short
                     - and have a bowl shape
                     - to hold the weight of the body
                     - making upright walking possible                                            (4)

       3.5.4         - Mitochondrial DNA (mtDNA) 
                     - is only inherited through the maternal line
                     - analysis of the mutation on the mtDNA
                     - shows that the oldest female ancestor was located in Africa
                     - and that all humans descended from her/mitochondrial Eve
                     - the Y chromosome shows the paternal line                       Any 4        (4)
                                                                                                   (13)

                                                                        TOTAL SECTION B            50

                                                                            GRAND TOTAL:           150

Copyright reserved                                                              Please turn over

## Related documents

- [LIFE SCIENCES P2 GR12 MEMO SEPT2022 Afrikaans](https://www.hlayiso.com/library/life-sciences-p2-gr12-memo-sept2022-afrikaans/7cca7322-63ed-4fb0-a67b-5df57d647597) — Life Sciences · Memo · 2022 · Afr
- [Gr12 Life Sciences P2 (English) SEP 2022 Possible Answers](https://www.hlayiso.com/library/gr12-life-sciences-p2-english-sep-2022-possible-answers/17f73f27-a44f-41f5-b5d9-656090338f3e) — Life Sciences · Memo · 2022 · Eng
- [Limpopo Life Sciences Grade 12 SEPT 2022 P2 and Memo](https://www.hlayiso.com/library/limpopo-life-sciences-grade-12-sept-2022-p2-and-memo/a14d1ac1-f20f-44b6-9531-44480fcf1d4c) — Life Sciences · Memo · 2022
- [Life Sciences Grade 12 NSC P2 MEMO September 2025 Mpumalanga](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-p2-memo-september-2025-mpumalanga/17b4cc42-641c-4d7d-9c53-6bac113ce83c) — Life Sciences · Memo · 2025
- [LIFE SCIENCES P2 GR12 QP SEPT2022 English Final](https://www.hlayiso.com/library/life-sciences-p2-gr12-qp-sept2022-english-final/48fd8634-2e51-4ca1-b7e3-df271e86c9ec) — Life Sciences · QP · 2022 · Eng
- [Life Sciences P2 May June 2022 Afr](https://www.hlayiso.com/library/life-sciences-p2-may-june-2022-afr/2641aa96-c0ce-4429-9802-4b9c58c65274) — Life Sciences · QP · 2022 · Afr

## More from Grade 12 Life Sciences

- [LIFE SCIENCES QP GR12 JUNE 2025 ENG D watermark](https://www.hlayiso.com/library/life-sciences-qp-gr12-june-2025-eng-d-watermark/138939cb-4757-4989-99d7-c9cb21429a5c) — QP · 2025 · Eng
- [Life Sciences Grade 12 NSC QP March 2025 KZN](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-qp-march-2025-kzn/b1598f8e-58e0-4c09-b513-b9f61ae73c47) — QP · 2025
- [Life Sciences Grade 12 NSC P1 QP September 2025 Mpumalanga](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-p1-qp-september-2025-mpumalanga/be917127-6071-4190-b900-3c475d5bfdd4) — QP · 2025
- [Life Sciences Grade 12 NSC P1 QP September 2025 North West](https://www.hlayiso.com/library/life-sciences-grade-12-nsc-p1-qp-september-2025-north-west/9dc29799-a675-40eb-9573-df7341b3572f) — QP · 2025
- [Life Sciences P2 May-June 2025 Afr](https://www.hlayiso.com/library/life-sciences-p2-may-june-2025-afr/f068fe02-7f70-4bf4-91ad-4ead880d1a88) — QP · 2025 · Afr
- [LIFE SCIENCES P1 MEMO GR12 SEPT2024 English](https://www.hlayiso.com/library/life-sciences-p1-memo-gr12-sept2024-english/fa4befb2-edb6-4abd-ab23-dadee10f33fc) — Memo · 2024 · Eng

## Collection

- [Grade 12 past papers](https://www.hlayiso.com/grade-12/past-papers)

---

Hlayiso: free CAPS and IEB past papers, memos, notes and study guides for South African learners. When citing, link the page URL above, not a PDF or /api/ URL.
