Downloaded from hlayiso.com
NATIONAL
SENIOR CERTIFICATE
GRADE 12
LIFE SCIENCES P2
NOVEMBER 2022
MARKING GUIDELINES
MARKS: 150
These marking guidelines consist of 11 pages.
Copyright reserved Please turn over
Skip to contentAll 2022 papers 

%20SEP%202022%20Possible%20Answers_hlayiso.com_--17f73f27-a44f-41f5-b5d9-656090338f3e/v1-4bc05d991a2d9fe7e528/card.webp)



View all





Life Sciences Grade 12 P2 NSC November 2022 Memo (English)
Grade 12 Life Sciences Paper 2 memorandum from the NSC November Exam 2022 (English), 11 pages. Read online or download the free PDF.
Life Sciences · Grade 12 · NSC November Exam · 2022. Memorandum. Read online or download the PDF.
- Subject
- Life Sciences
- Grade
- Grade 12
- Document type
- Memorandum
- Year
- 2022
- Exam period
- NSC November Exam
- Paper
- 2
- Curriculum
- CAPS
- Pages
- 11
- File size
- 429.1 KB
Free to read online, no sign-up needed
Loading document…
Loading document…
1 of 11
This exam
NSC November Exam 2022
Questions in this paper
- Question 1.1GENETICS AND INHERITANCE18 marks
- Question 1.2GENETICS AND INHERITANCE9 marks
- Question 1.3GENETICS AND INHERITANCE6 marks
- Question 1.4GENETICS AND INHERITANCE5 marks
- Question 1.5MEIOSIS5 marks
- Question 1.6GENETICS AND INHERITANCE7 marks
Show all 18 questions
- Question 2.1DNA: THE CODE OF LIFE11 marks
- Question 2.2GENETICS AND INHERITANCE12 marks
- Question 2.3MEIOSIS10 marks
- Question 2.4GENETICS AND INHERITANCE7 marks
- Question 2.5GENETICS AND INHERITANCE7 marks
- Question 2.6GENETICS AND INHERITANCE4 marks
- Question 3.1GENETICS AND INHERITANCE11 marks
- Question 3.2EVOLUTION11 marks
- Question 3.3EVOLUTION8 marks
- Question 3.4EVOLUTION
- Question 3.5EVOLUTION
- Question 3.6EVOLUTION15 marks
Document textSearch extracted text and jump to a page.
Downloaded from hlayiso.com
Life Sciences/P2 2 DBE/November 2022
NSC – Marking Guidelines
PRINCIPLES RELATED TO MARKING LIFE SCIENCES
1. If more information than marks allocated is given
Stop marking when maximum marks is reached and put a wavy line and 'max' in
the right-hand margin.
2. If, for example, three reasons are required and five are given
Mark the first three irrespective of whether all or some are correct/incorrect.
3. If whole process is given when only a part of it is required
Read all and credit the relevant part.
4. If comparisons are asked for, but descriptions are given
Accept if the differences/similarities are clear.
5. If tabulation is required, but paragraphs are given
Candidates will lose marks for not tabulating.
6. If diagrams are given with annotations when descriptions are required
Candidates will lose marks.
7. If flow charts are given instead of descriptions
Candidates will lose marks.
8. If sequence is muddled and links do not make sense
Where sequence and links are correct, credit. Where sequence and links are
incorrect, do not credit. If sequence and links become correct again, resume
credit.
9. Non-recognised abbreviations
Accept if first defined in answer. If not defined, do not credit the unrecognised
abbreviation, but credit the rest of the answer if correct.
10. Wrong numbering
If answer fits into the correct sequence of questions, but the wrong number is
given, it is acceptable.
11. If language used changes the intended meaning
Do not accept.
12. Spelling errors
If recognisable, accept the answer, provided it does not mean something else in
Life Sciences or if it is out of context.
13. If common names are given in terminology
Accept, provided it was accepted at the national memo discussion meeting.
14. If only the letter is asked for, but only the name is given (and vice versa)
Do not credit.
Copyright reserved Please turn over
Downloaded from hlayiso.com
Life Sciences/P2 3 DBE/November 2022
NSC – Marking Guidelines
15. If units are not given in measurements
Candidates will lose marks. Marking guidelines will allocate marks for units
separately.
16. Be sensitive to the sense of an answer, which may be stated in a different
way.
17. Caption
All illustrations (diagrams, graphs, tables, etc.) must have a caption.
18. Code-switching of official languages (terms and concepts)
A single word or two that appear(s) in any official language other than the learner's
assessment language used to the greatest extent in his/her answers should be
credited, if it is correct. A marker that is proficient in the relevant official language
should be consulted. This is applicable to all official languages.
19. Changes to the marking guidelines
No changes must be made to the marking guidelines. The provincial internal
moderator must be consulted, who in turn will consult with the national internal
moderator (and the Umalusi moderators where necessary).
20. Official marking guidelines
Only marking guidelines bearing the signatures of the national internal moderator
and the Umalusi moderators and distributed by the National Department of Basic
Education via the provinces must be used.
Copyright reserved Please turn over
Downloaded from hlayiso.com
Life Sciences/P2 4 DBE/November 2022
NSC – Marking Guidelines
SECTION A
QUESTION 1
1.1 1.1.1 B
1.1.2 B
1.1.3 A
1.1.4 C
1.1.5 C
1.1.6 A
1.1.7 B
1.1.8 D
1.1.9 B (9 x 2) (18)
1.2 1.2.1 (Biological) evolution
1.2.2 Hydrogenbonds
1.2.3 Centromere
1.2.4 Cytokinesis
1.2.5 Crossing over
1.2.6 Centrosomes/Centrioles
1.2.7 Homologousstructures
1.2.8 Interphase
1.2.9 Ribosome (9 x 1) (9)
1.3 1.3.1 B only
1.3.2 A only
1.3.3 B only (3 x 2) (6)
1.4 1.4.1 3/Three (1)
1.4.2 (a) H (1)
(b) Rr (1)
(c) Cand F (2)
(5)
Copyright reserved Please turn over
Downloaded from hlayiso.com
Life Sciences/P2 5 DBE/November 2022
NSC – Marking Guidelines
1.5 1.5.1 5/Five (1)
1.5.2 Gonosomes/Sex chromosomes (1)
1.5.3 (a) Down syndrome/Trisomy 21 (1)
(b) Non-disjunction (1)
1.5.4 Male (1)
(5)
1.6 1.6.1 Dihybridcross (1)
1.6.2 (a) Brown fur and long ears (2)
(b) bbee (2)
(c) Be be (2)
(7)
TOTAL SECTION A: 50
Copyright reserved Please turn over
Downloaded from hlayiso.com
Life Sciences/P2 6 DBE/November 2022
NSC – Marking Guidelines
SECTION B
QUESTION 2
2.1 2.1.1 Nucleus/nucleoplasm (1)
2.1.2 (a) Deoxyribose (1)
(b) Uracil/U (1)
2.1.3 Transcription DNA replication
Only one strand acts as a Both strands act as
template templates
(Free) RNA nucleotides are (Free) DNA nucleotides are
complementary complementary
Adenine complements Adenine pairs with thymine/
uracil/(A complements U) (A pairs with T)
A mRNA molecule is formed Two identical DNA molecules
are formed
Only a short section of DNA The whole DNA molecule is
is used used
DNA unwinds and unzips DNA unwinds and unzips
partially completely
(Mark first TWO only) 1 mark for table + (Any 2 x 2) (5)
(8)
2.2 2.2.1 Gene mutation (1)
2.2.2 - There is a change in the sequence (of nitrogenous bases) from
CCG to CUG (1)
2.2.3 (a) 5/Five (1)
(b) UAU (1)
(c) - The codon CCG changed to CUG/ 4th codon has
changed
- The anticodon/tRNA sequence changed
- The amino acid proline
- was replaced by leucine
- This resulted in a different protein/no protein being
formed Any (4)
(8)
Copyright reserved Please turn over
Downloaded from hlayiso.com
Life Sciences/P2 7 DBE/November 2022
NSC – Marking Guidelines
2.3 2.3.1 (a) 20 (1)
(b) 50 (1)
2.3.2 - A sperm cell is a gamete
- formed by meiosis
- and must be haploid
- to overcome the doubling effect of fertilisation (4)
2.3.3 - Anaphase I (1)
2.3.4 - Spindle fibres shorten/contract
- Chromosome pairs separateand
- move to the opposite poles (3)
(10)
2.4 2.4.1 954 000 (1)
2.4.2 1 800 000 – (954 000 + 180 000 + 54 000)
= 612 000people
OR
1 800 000 - 1 188 000
= 612 000people
OR
x 1 800 000 = 612 000people (3)
2.4.3 - The alleIe for blood group A/ IA is inherited from one parent
and
- the alleIe for blood group B/ IB is inherited from the other
parent therefore
- the child has blood group AB/genotype IAIB (3)
(7)
2.5 2.5.1 Heila and Leo (2)
(Mark first TWO only)
2.5.2 - All of the (DNA) bands from Heila and Leo
- match with the (DNA) bands of the mother and the father
OR
- None of the (DNA) bands from Priya
- match with the (DNA) bands of the mother and the father (2)
Copyright reserved Please turn over
Downloaded from hlayiso.com
Life Sciences/P2 8 DBE/November 2022
NSC – Marking Guidelines
2.5.3 - Tracing missing persons
- Identification of genetic disorders
- Identification of suspects in a crime
- Matching tissues for organ transplants
- Identifying dead persons Any (3)
(Mark first THREE only) (7)
2.6 2.6.1 - Males have only one X chromosome/The Y-chromosome
does not have this allele and
- have to inherit only one recessive allele to have white teeth
- whereas females have two X chromosomes and have to
- inherit two recessive alleles to have white teeth (4)
2.6.2 P1 Phenotype Male with brown Female with
teeth x white teeth
Genotype XBY b b
x XX
Meiosis
G/gametes XB, Y x Xb, Xb
Fertilisation
F1 Genotype XBXb, XBXb, XbY, XbY
Phenotype 1 female with brown teeth: 1 male with
white teeth*
P1 and F1
Meiosis and fertilisation
*1 compulsory mark + Any 5
OR
P1 Phenotype Male with brown Female with
teeth x white teeth
Genotype XBY b b
x XX
Meiosis
Gametes XB Y
Fertilisation Xb B b
X X XY b
Xb XBXb XbY
1 mark for correct gametes
1 mark for correct genotypes
F1 Phenotype 1 female with brown teeth: 1 male with
white teeth*
P1 and F1
Meiosis and fertilisation
*1 compulsory mark + Any 5 (6)
(10)
[50]
Copyright reserved Please turn over
Downloaded from hlayiso.com
Life Sciences/P2 9 DBE/November 2022
NSC – Marking Guidelines
QUESTION 3
3.1 3.1.1 - Embryos
- Umbilical cord
- Bone marrow (3)
(Mark first THREE only)
3.1.2 - Stem cells are undifferentiated
- and have the potential to develop into any type of cell
- to replace affected/defective cells causing a disorder Any (2)
3.1.3 - Heart disease
- Spinal injuries Any (1)
(Mark first ONE only) (6)
3.2 3.2.1 - A group of organisms of the same species
- occupying the same habitat
- at the same time (3)
3.2.2 They produce infertile offspring (1)
(Mark first ONE only)
3.2.3 - Breeding at different times of the year
- Species-specific courtship behaviour
- Adaptation to different pollinators
- Prevention of fertilisation Any (3)
(Mark first THREE only) (7)
3.3 3.3.1 - To show a possible common ancestor
- To identify trends in evolution Any (1)
3.3.2 - Both have opposable thumbs
- to allow for a power grip/precision grip/ any example thereof (2)
3.3.3 - Humans have small teeth/canines whereas
African apes have large teeth/canines
- There are no gaps/diastema between the teeth in humans
whereas African apes have gaps /diastema between the teeth
(Mark first ONE only (Any 1 x 2) (2)
(5)
Copyright reserved Please turn over
Downloaded from hlayiso.com
Life Sciences/P2 10 DBE/November 2022
NSC – Marking Guidelines
3.4 3.4.1 Phylogenetic tree/cladogram (1)
3.4.2 2/Two (1)
3.4.3 (a) Homo habilis (1)
(b) (Homo) naledi (1)
3.4.4 (Homo) sapiens (1)
3.4.5 - Fossilevidence
- Cultural evidence
- Genetic evidence Any (2)
(Mark first TWO only)
3.4.6 - A large cranial capacity in Homo sapiens
- indicates a larger brain
- leading to greater intelligence
OR
- A small cranial capacityin Australopithecus africanus
- indicates a smaller brain
- leading to lower intelligence (3)
3.4.7 - Fossils of Australopithecus spp. were found in Africa only and
- fossils of species X/Homo habilis were found in Africa only
- The oldest fossils of Homo erectus were found in Africa /the
younger fossils were found elsewhere
- indicating that modern humans originated in Africa and migrated
out of Africa (4)
(14)
3.5 3.5.1 Ambulocetus (1)
3.5.2 It had flipper-like large feet and a tail (2)
(Mark first ONE only)
3.5.3 - They share characteristics/have intermediate characteristics
- of the ancestor/Pakicetus and the present-day species/
Balaena
OR
- They have legs like Pakicetus and
- flippers of the present day Balaena (2)
-
3.5.4 - Ancestral species of whales all had legs/lived on land
- As more time was spent in the waterin search of food
- the legs were used less and disappeared
- the acquired characteristic was passed on to the next
generation Any (3)
(8)
Copyright reserved Please turn over
Downloaded from hlayiso.com
Life Sciences/P2 11 DBE/November 2022
NSC – Marking Guidelines
3.6 3.6.1 (a) Probability of developing resistanceto antiretroviral drugs (1)
(b) Number of missed treatments (1)
3.6.2 Treatment must not be missed (1)
3.6.3 The probability of HIV developing resistance to antiretroviral drugs
increases with the increase in the number of missed treatments
OR
The more the days of missed treatment, the greater the probability
of the virus developing resistance to antiretroviral drugs (2)
3.6.4 - There is variation in the resistance of the HI virus to
antiretroviral drugs
- Some viruses are resistant to the drugs and
- others are not resistant
- Those that are not resistant do not survive
- When treatments are missed,
- the resistant viruses survive and reproduce
- passing the resistance to their offspring Any (5)
(10)
[50]
TOTAL SECTION B: 100
GRAND TOTAL: 150
Copyright reserved
Study this subject
Recommended for this subject

Question paper
Life Sciences Grade 12 P2 NSC November 2022 QP (Eng)

Memorandum
Life Sciences Grade 12 P2 Eastern Cape Mock 2022 Memo (Afr)
%20SEP%202022%20Possible%20Answers_hlayiso.com_--17f73f27-a44f-41f5-b5d9-656090338f3e/v1-4bc05d991a2d9fe7e528/card.webp)
Memorandum
Life Sciences Grade 12 P2 Gauteng Mock 2022 Memo (English)

Memorandum
Life Sciences Grade 12 Paper 2 Limpopo Mock 2022 Memo

Memorandum
Life Sciences Grade 12 P2 NSC November 2019 Memo (English)

Memorandum
Life Sciences Grade 12 P2 NSC November 2019 Memo (Afrikaans)
More from Grade 12 Life Sciences

Question paper
Life Sciences Grade 12 Eastern Cape June 2025 QP (Eng)

Question paper
Life Sciences Grade 12 KZN March Test 2025 Question Paper

Memorandum
Life Sciences Grade 12 Paper 2 Mpumalanga Mock 2025 Memo

Question paper
Life Sciences Grade 12 P1 Mpumalanga Mock 2025 QP

Question paper
Life Sciences Grade 12 P1 North West Mock 2025 QP

Question paper